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Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…

Neurons and Cognition · Quantitative Biology 2025-09-18 Aaron Herrera , Hina Shaheen

This work proposes improvements in the electroencephalogram (EEG) recording protocols for motor imagery through the introduction of actual motor movement and/or somatosensory cues. The results obtained demonstrate the advantage of requiring…

Neurons and Cognition · Quantitative Biology 2020-03-24 Jerrin Thomas Panachakel , Nandagopal Netrakanti Vinayak , Maanvi Nunna , A. G. Ramakrishnan , Kanishka Sharma

Real-time decoding of neural activity is central to neuroscience and neurotechnology applications, from closed-loop experiments to brain-computer interfaces, where models are subject to strict latency constraints. Traditional methods,…

Neurons and Cognition · Quantitative Biology 2025-11-10 Avery Hee-Woon Ryoo , Nanda H. Krishna , Ximeng Mao , Mehdi Azabou , Eva L. Dyer , Matthew G. Perich , Guillaume Lajoie

Simulating Standardized Patients with cognitive impairment offers a scalable and ethical solution for clinical training. However, existing methods rely on discrete prompt engineering and fail to capture the heterogeneity of deficits across…

Artificial Intelligence · Computer Science 2026-04-17 Weikang Zhang , Zimo Zhu , Zhichuan Yang , Chen Huang , Wenqiang Lei , See-Kiong Ng

Electrical motors are the most important source of mechanical energy in the industrial world. Their modeling traditionally relies on a physics-based approach, which aims at taking their complex internal dynamics into account. In this paper,…

Machine Learning · Computer Science 2020-10-13 Sagar Verma , Nicolas Henwood , Marc Castella , Francois Malrait , Jean-Christophe Pesquet

Personalized treatments are gaining momentum across all fields of medicine. Precision medicine can be applied to neuromodulatory techniques, where focused brain stimulation treatments such as repetitive transcranial magnetic stimulation…

Robot navigation around humans can be a challenging problem since human movements are hard to predict. Stochastic model predictive control (MPC) can account for such uncertainties and approximately bound the probability of a collision to…

Robotics · Computer Science 2024-07-22 Yunfan Gao , Florian Messerer , Niels van Duijkeren , Moritz Diehl

We present a contact-implicit planning approach that can generate contact-interaction trajectories for non-prehensile manipulation problems without tuning or a tailored initial guess and with high success rates. This is achieved by…

Robotics · Computer Science 2022-10-19 Maozhen Wang , Aykut Ozgun Onol , Philip Long , Taskin Padir

Whereas most brain-computer interface research has focused on decoding neural signals into behavior or intent, the reverse challenge-using controlled stimuli to steer brain activity-remains far less understood, particularly in the visual…

Neural and Evolutionary Computing · Computer Science 2026-03-03 Dongyang Li , Kunpeng Xie , Mingyang Wu , Yiwei Kong , Jiahua Tang , Haoyang Qin , Chen Wei , Quanying Liu

In pedestrian dynamics, the internal drive that propels individuals toward their goals is typically captured by a single, fixed parameter, the desired walking speed. This simplification overlooks that motivation fluctuates in response to…

Physics and Society · Physics 2026-05-04 Ezel Üsten , Anna Sieben , Mohcine Chraibi , Armin Seyfried

Coordinate-based meta-analysis combines evidence from a collection of Neuroimaging studies to estimate brain activation. In such analyses, a key practical challenge is to find a computationally efficient approach with good statistical…

We show that dynamical gain modulation of neurons' stimulus response is described as an information-theoretic cycle that generates entropy associated with the stimulus-related activity from entropy produced by the modulation. To articulate…

Neurons and Cognition · Quantitative Biology 2017-12-29 Hideaki Shimazaki

Advances in large-scale neural recordings have expanded our ability to describe the activity of distributed brain circuits. However, understanding how neural population dynamics differ across regions and behavioral contexts remains…

Precise control of signal propagation in modular neural networks represents a fundamental challenge in computational neuroscience. We establish a framework for identifying optimal control nodes that maximize stimulus transmission between…

Neurons and Cognition · Quantitative Biology 2025-08-18 Bulat Batuev , Arsenii Onuchin , Sergey Sukhov

Functional neuroimaging can measure the brain?s response to an external stimulus. It is used to perform brain mapping: identifying from these observations the brain regions involved. This problem can be cast into a linear supervised…

Machine Learning · Computer Science 2012-07-03 Gael Varoquaux , Alexandre Gramfort , Bertrand Thirion

This paper studies the phenomenon of conduction block in model neurons using high-frequency biphasic stimulation (HFBS). The focus is investigating the triggering of undesired onset action potentials when the HFBS is turned on. The approach…

Neurons and Cognition · Quantitative Biology 2025-12-29 Eduardo Cerpa , Nathaly Corrales , Matías Courdurier , Leonel E. Medina , Esteban Paduro

Living systems process sensory data to facilitate adaptive behaviour. A given sensor can be stimulated as the result of internally driven activity, or by purely external (environmental) sources. It is clear that these inputs are processed…

Neural and Evolutionary Computing · Computer Science 2022-05-16 James Garner , Matthew Egbert

This paper proposes a novel alternative to existing sim-to-real methods for training control policies with simulated experiences. Unlike prior methods that typically rely on domain randomization over a fixed finite set of parameters, the…

Robotics · Computer Science 2026-03-26 Junhyeok Rui Cha , Woohyun Cha , Jaeyong Shin , Donghyeon Kim , Jaeheung Park

Current studies about motor imagery based rehabilitation training systems for stroke subjects lack an appropriate analytic method, which can achieve a considerable classification accuracy, at the same time detects gradual changes of imagery…

Machine Learning · Statistics 2014-09-19 Hao Zhang , Liqing Zhang

The application of closed-loop approaches in systems neuroscience and therapeutic stimulation holds great promise for revolutionizing our understanding of the brain and for developing novel neuromodulation therapies to restore lost…

Signal Processing · Electrical Eng. & Systems 2021-10-12 Bingzhao Zhu , Uisub Shin , Mahsa Shoaran