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Identifying cortical regions critical for speech is essential for safe brain surgery in or near language areas. While Electrical Stimulation Mapping (ESM) remains the clinical gold standard, it is invasive and time-consuming. To address…

Closed-loop brain stimulation refers to capturing neurophysiological measures such as electroencephalography (EEG), quickly identifying neural events of interest, and producing auditory, magnetic or electrical stimulation so as to interact…

Signal Processing · Electrical Eng. & Systems 2022-10-12 Nicolas Valenchon , Yann Bouteiller , Hugo R. Jourde , Xavier L'Heureux , Milo Sobral , Emily B. J. Coffey , Giovanni Beltrame

To maintain a user's sense of agency (SoA) when working with a physical motor augmentation device, the actuation must align with the user's intentions. In experiments, this is often achieved using stimulus-response paradigms where the motor…

Human-Computer Interaction · Computer Science 2025-06-17 Lukas Gehrke , Leonie Terfurth , Klaus Gramann

Magnetic stimulation is a standard tool in brain research and many fields of neurology, as well as psychiatry. From a physical perspective, one key aspect of this method is the inefficiency of available setups. Whereas the spatial field…

Medical Physics · Physics 2011-06-20 Stefan M. Goetz , Nam C. Truong , Manuel G. Gerhofer , Thomas Weyh , Hans-Georg Herzog

Objective: We present magnetomyograms (MMG) of TMS-evoked movement in a human hand, together with a simultaneous surface electromyograph (EMG) and electroencephalograph (EEG) data. Approach: We combined TMS with non-contact magnetic…

We present a neural network approach for closed-loop deep brain stimulation (DBS). We cast the problem of finding an optimal neurostimulation strategy as a control problem. In this setting, control policies aim to optimize therapeutic…

Optimization and Control · Mathematics 2023-11-14 Malvern Madondo , Deepanshu Verma , Lars Ruthotto , Nicholas Au Yong

Noninvasive brain stimulation (NIBS) by quasistatic electromagnetic means is presently comprised of two methods: Magnetic induction methods (Transcranial magnetic perturbation or TMP) and electrical contact methods (Transcranial electric…

Medical Physics · Physics 2020-06-11 D. J. Sheltraw , B. Inglis , L. Labruna , R. Ivry

Cortical slow oscillations occur in the mammalian brain during deep sleep and have been shown to contribute to memory consolidation, an effect that can be enhanced by electrical stimulation. As the precise underlying working mechanisms are…

Neurons and Cognition · Quantitative Biology 2013-12-31 Arne Weigenand , Thomas Martinetz , Jens Christian Claussen

Objective: The objective of this study is to develop and evaluate a systematic approach to optimize Deep Brain Stimulation (DBS) parameters, addressing the challenge of identifying patient-specific settings and optimal stimulation targets…

Systems and Control · Electrical Eng. & Systems 2026-01-13 Anna Franziska Frigge , Lina Uggla , Elena Jiltsova , Markus Fahlström , Dag Nyholm , Alexander Medvedev

Recordings in the human medial temporal lobe have found many neurons that respond to pictures (and related stimuli) of just one particular person out of those presented. It has been proposed that these are concept cells, responding to just…

Neurons and Cognition · Quantitative Biology 2015-07-22 Andrew Magyar , John Collins

The models in statistical physics such as an Ising model offer a convenient way to characterize stationary activity of neural populations. Such stationary activity of neurons may be expected for recordings from in vitro slices or…

Neurons and Cognition · Quantitative Biology 2017-05-05 Christian Donner , Klaus Obermayer , Hideaki Shimazaki

As the embodiment gap between a robot and a human narrows, new opportunities arise to leverage datasets of humans interacting with their surroundings for robot learning. We propose a novel technique for training sensorimotor policies with…

Robotics · Computer Science 2025-08-27 Himanshu Gaurav Singh , Pieter Abbeel , Jitendra Malik , Antonio Loquercio

Objective: A major challenge in designing closed-loop brain-computer interfaces is finding optimal stimulation patterns as a function of ongoing neural activity for different subjects and objectives. Approach: To achieve goal-directed…

Neurons and Cognition · Quantitative Biology 2023-03-22 Matthew J. Bryan , Linxing Preston Jiang , Rajesh P N Rao

This thesis is dedicated to the statistical analysis of multi-sub ject fMRI data, with the purpose of identifying bain structures involved in certain cognitive or sensori-motor tasks, in a reproducible way across sub jects. To overcome…

Applications · Statistics 2010-05-19 Merlin Keller , Alexis Roche , Marc Lavielle

Coordinated human movement depends on the integration of multisensory inputs, sensorimotor transformation, and motor execution, as well as sensory feedback resulting from body-environment interaction. Building dynamic models of the…

Neurons and Cognition · Quantitative Biology 2025-06-03 Chenhui Zuo , Guohao Lin , Chen Zhang , Shanning Zhuang , Yanan Sui

Objective: Numerical modeling of electric fields induced by transcranial alternating current stimulation (tACS) is currently a part of the standard procedure to predict and understand neural response. Quasi-static approximation for electric…

The Electro-Encephalo-Graphy (EEG) technique consists of estimating the cortical distribution of signals over time of electrical activity and also of locating the zones of primary sensory projection. Moreover, it is able to record…

Signal Processing · Electrical Eng. & Systems 2021-12-02 Ridha jarray , Abir Hadriche , Cokri ben Amar , Nawel Jmail

Living organisms interact with their surroundings in a closed-loop fashion, where sensory inputs dictate the initiation and termination of behaviours. Even simple animals are able to develop and execute complex plans, which has not yet been…

Robotics · Computer Science 2025-01-30 Giulia Lafratta , Bernd Porr , Christopher Chandler , Alice Miller

Event-triggered model predictive control (eMPC) is a popular optimal control method with an aim to alleviate the computation and/or communication burden of MPC. However, it generally requires priori knowledge of the closed-loop system…

Robotics · Computer Science 2022-08-23 Fengying Dang , Dong Chen , Jun Chen , Zhaojian Li

In this article, a biophysically realistic model of a soft octopus arm with internal musculature is presented. The modeling is motivated by experimental observations of sensorimotor control where an arm localizes and reaches a target. Major…

Systems and Control · Electrical Eng. & Systems 2025-09-11 Tixian Wang , Udit Halder , Ekaterina Gribkova , Rhanor Gillette , Mattia Gazzola , Prashant G. Mehta