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Topological Data Analysis (TDA) is an emergent field that aims to discover topological information hidden in a dataset. TDA tools have been commonly used to create filters and topological descriptors to improve Machine Learning (ML)…

Machine Learning · Computer Science 2022-02-07 Rolando Kindelan , José Frías , Mauricio Cerda , Nancy Hitschfeld

The development of machine learning models based on computed tomography (CT) imaging has been a major focus due to the promise that imaging holds for diagnosis, staging, and prognostication. These models often rely on the extraction of…

Modern deep neural networks have achieved great successes in medical image analysis. However, the features captured by convolutional neural networks (CNNs) or Transformers tend to be optimized for pixel intensities and neglect key…

Computer Vision and Pattern Recognition · Computer Science 2023-11-30 Yaopeng Peng , Hongxiao Wang , Milan Sonka , Danny Z. Chen

Topological correctness is critical for segmentation of tubular structures, which pervade in biomedical images. Existing topological segmentation loss functions are primarily based on the persistent homology of the image. They match the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Bo Wen , Haochen Zhang , Dirk-Uwe G. Bartsch , William R. Freeman , Truong Q. Nguyen , Cheolhong An

Topological structures in image data, such as connected components and loops, play a crucial role in understanding image content (e.g., biomedical objects). % Despite remarkable successes of numerous image processing methods that rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Pengfei Gu , Hongxiao Wang , Yejia Zhang , Huimin Li , Chaoli Wang , Danny Chen

The performance of diagnostic Computer-Aided Design (CAD) systems for retinal diseases depends on the quality of the retinal images being screened. Thus, many studies have been developed to evaluate and assess the quality of such retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Saif Khalid , Hatem A. Rashwan , Saddam Abdulwahab , Mohamed Abdel-Nasser , Facundo Manuel Quiroga , Domenec Puig

Recent advancements in ophthalmology foundation models such as RetFound have demonstrated remarkable diagnostic capabilities but require massive datasets for effective pre-training, creating significant barriers for development and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Qingshan Hou , Meng Wang , Peng Cao , Zou Ke , Xiaoli Liu , Huazhu Fu , Osmar R. Zaiane

This work describes an automatic methodology to discriminate between individuals with the genetic disorder Pitt-Hopkins syndrome (PTHS), and healthy individuals. As input data, the methodology accepts unconstrained frontal facial…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Elena D'Amato , Constantino Carlos Reyes-Aldasoro , Maria Felicia Faienza , Marcella Zollino

Retinal image plays a crucial role in diagnosing various diseases, as retinal structures provide essential diagnostic information. However, effectively capturing structural features while integrating them with contextual information from…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Xinwei Luo , Songlin Zhao , Yun Zong , Yong Chen , Gui-shuang Ying , Lifang He

Recently, a number of competitive methods have tackled unsupervised representation learning by maximising the mutual information between the representations produced from augmentations. The resulting representations are then invariant to…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Luke Nicholas Darlow , Amos Storkey

Foundation models are reshaping computational histopathology, yet their value for whole-slide image retrieval relative to strong patch-based and supervised aggregation baselines remains unclear. We benchmarked ten pipelines on 9,387…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Tianhao Lei , Parsa Esmaeilkhani , Saghir Alfasly , Wataru Uegami , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

Diabetic Retinopathy (DR) refers to a barrier that takes place in diabetes mellitus damaging the blood vessel network present in the retina. This may endanger the subjects' vision if they have diabetes. It can take some time to perform a DR…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 V. Banupriya , S. Anusuya

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Fundus image captures rear of an eye, and which has been studied for the diseases identification, classification, segmentation, generation, and biological traits association using handcrafted, conventional, and deep learning methods. In…

We propose an extension of popular descriptors based on gradient orientation histograms (HOG, computed in a single image) to multiple views. It hinges on interpreting HOG as a conditional density in the space of sampled images, where the…

Computer Vision and Pattern Recognition · Computer Science 2013-11-26 Jingming Dong , Jonathan Balzer , Damek Davis , Joshua Hernandez , Stefano Soatto

Developing reliable methods to discriminate different transient brain states that change over time is a key neuroscientific challenge in brain imaging studies. Topological data analysis (TDA), a novel framework based on algebraic topology,…

Neurons and Cognition · Quantitative Biology 2023-12-19 Moo K. Chung , Soumya Das , Hernando Ombao

Comparison of data representations is a complex multi-aspect problem that has not enjoyed a complete solution yet. We propose a method for comparing two data representations. We introduce the Representation Topology Divergence (RTD),…

Machine Learning · Computer Science 2023-05-05 Serguei Barannikov , Ilya Trofimov , Nikita Balabin , Evgeny Burnaev

Optical coherence tomography (OCT) is one of the non-invasive and easy-to-acquire biomarkers (the thickness of the retinal layers, which is detectable within OCT scans) being investigated to diagnose Alzheimer's disease (AD). This work aims…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Paria Jeihouni , Omid Dehzangi , Annahita Amireskandari , Ali Dabouei , Ali Rezai , Nasser M. Nasrabadi

Deep learning models have the capacity to fundamentally revolutionize medical imaging analysis, and they have particularly interesting applications in computer-aided diagnosis. We attempt to use deep learning neural networks to diagnose…

Machine Learning · Computer Science 2020-02-24 Rohit Jammula , Vishnu Rajan Tejus , Shreya Shankar

Recently, human pose estimation mainly focuses on how to design a more effective and better deep network structure as human features extractor, and most designed feature extraction networks only introduce the position of each anatomical…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Zhangjian Ji , Zilong Wang , Ming Zhang , Yapeng Chen , Yuhua Qian
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