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In medical imaging, generative models are increasingly relied upon for two distinct but equally critical tasks: reconstruction, where the goal is to restore medical imaging (usually inverse problems like inpainting or superresolution), and…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Niklas Bubeck , Yundi Zhang , Suprosanna Shit , Daniel Rueckert , Jiazhen Pan

Controllable layout generation aims at synthesizing plausible arrangement of element bounding boxes with optional constraints, such as type or position of a specific element. In this work, we try to solve a broad range of layout generation…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Naoto Inoue , Kotaro Kikuchi , Edgar Simo-Serra , Mayu Otani , Kota Yamaguchi

Creating large-scale datasets for training high-performance generative models is often prohibitively expensive, especially when associated attributes or annotations must be provided. As a result, merging existing datasets has become a…

Machine Learning · Statistics 2026-03-31 Yanfeng Yang , Kenji Fukumizu

Stable diffusion models represent the state-of-the-art in data synthesis across diverse domains and hold transformative potential for applications in science and engineering, e.g., by facilitating the discovery of novel solutions and…

Machine Learning · Computer Science 2025-10-23 Stefano Zampini , Jacob K. Christopher , Luca Oneto , Davide Anguita , Ferdinando Fioretto

Understanding the structure of real data is paramount in advancing modern deep-learning methodologies. Natural data such as images are believed to be composed of features organized in a hierarchical and combinatorial manner, which neural…

Machine Learning · Statistics 2024-12-25 Antonio Sclocchi , Alessandro Favero , Matthieu Wyart

Diffusion models have demonstrated remarkable performance in generating unimodal data across various tasks, including image, video, and text generation. On the contrary, the joint generation of multimodal data through diffusion models is…

Machine Learning · Computer Science 2025-06-16 Kevin Rojas , Yuchen Zhu , Sichen Zhu , Felix X. -F. Ye , Molei Tao

Generative diffusion models have achieved remarkable success in producing high-quality images. However, these models typically operate in continuous intensity spaces, diffusing independently across pixels and color channels. As a result,…

Graphics · Computer Science 2025-05-20 Javier E. Santos , Agnese Marcato , Roman Colman , Nicholas Lubbers , Yen Ting Lin

Diffusion Models have become a cornerstone of modern generative AI for their exceptional generation quality and controllability. However, their inherent \textit{multi-step iterations} and \textit{complex backbone networks} lead to…

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Lakshmi Nair

Single-cell RNA sequencing (scRNA-seq) data are important for studying the laws of life at single-cell level. However, it is still challenging to obtain enough high-quality scRNA-seq data. To mitigate the limited availability of data,…

Quantitative Methods · Quantitative Biology 2024-03-06 Erpai Luo , Minsheng Hao , Lei Wei , Xuegong Zhang

Spatiotemporal data analysis is pivotal across various domains, such as transportation, meteorology, and healthcare. The data collected in real-world scenarios are often incomplete due to device malfunctions and network errors.…

Machine Learning · Computer Science 2024-03-25 Yakun Chen , Kaize Shi , Zhangkai Wu , Juan Chen , Xianzhi Wang , Julian McAuley , Guandong Xu , Shui Yu

Mesh generation is of great value in various applications involving computer graphics and virtual content, yet designing generative models for meshes is challenging due to their irregular data structure and inconsistent topology of meshes…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Zhaoyang Lyu , Jinyi Wang , Yuwei An , Ya Zhang , Dahua Lin , Bo Dai

Augmentation for dense prediction typically relies on either sample mixing or generative synthesis. Mixing improves robustness but misaligned masks yield soft label ambiguity. Diffusion synthesis increases apparent diversity but, when…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Pengyu Jie , Wanquan Liu , Rui He , Yihui Wen , Deyu Meng , Chenqiang Gao

Discriminative classifiers have become a foundational tool in deep learning for medical imaging, excelling at learning separable features of complex data distributions. However, these models often need careful design, augmentation, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Gian Mario Favero , Parham Saremi , Emily Kaczmarek , Brennan Nichyporuk , Tal Arbel

Deep generative models have significantly advanced medical imaging analysis by enhancing dataset size and quality. Beyond mere data augmentation, our research in this paper highlights an additional, significant capacity of deep generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Xiaodan Xing , Junzhi Ning , Yang Nan , Guang Yang

Diffusion models for continuous data gained widespread adoption owing to their high quality generation and control mechanisms. However, controllable diffusion on discrete data faces challenges given that continuous guidance methods do not…

Spatial control methods using additional modules on pretrained diffusion models have gained attention for enabling conditional generation in natural images. These methods guide the generation process with new conditions while leveraging the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Suhyun Ahn , Wonjung Park , Jihoon Cho , Seunghyuck Park , Jinah Park

We demonstrate how conditional generation from diffusion models can be used to tackle a variety of realistic tasks in the production of music in 44.1kHz stereo audio with sampling-time guidance. The scenarios we consider include…

Sound · Computer Science 2023-12-06 Mark Levy , Bruno Di Giorgi , Floris Weers , Angelos Katharopoulos , Tom Nickson

Synthesizing realistic microstructure images conditioned on processing parameters is crucial for understanding process-structure relationships in materials design. However, this task remains challenging due to limited training micrographs…

Materials Science · Physics 2025-11-21 Hoang Cuong Phan , Minh Tien Tran , Chihun Lee , Hoheok Kim , Sehyeok Oh , Dong-Kyu Kim , Ho Won Lee

While modern diffusion models excel at generating high-quality and diverse images, they still struggle with high-fidelity compositional and multimodal control, particularly when users simultaneously specify text prompts, subject references,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Yusuf Dalva , Guocheng Gordon Qian , Maya Goldenberg , Tsai-Shien Chen , Kfir Aberman , Sergey Tulyakov , Pinar Yanardag , Kuan-Chieh Jackson Wang