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The variational autoencoder (VAE) is a popular, deep, latent-variable model (DLVM) due to its simple yet effective formulation for modeling the data distribution. Moreover, optimizing the VAE objective function is more manageable than other…

Machine Learning · Computer Science 2025-01-28 Surojit Saha , Sarang Joshi , Ross Whitaker

Score matching (SM) is a convenient method for training flexible probabilistic models, which is often preferred over the traditional maximum-likelihood (ML) approach. However, these models are less interpretable than normalized models; as…

Machine Learning · Statistics 2022-10-25 Li Kevin Wenliang

Unsupervised multivariate time series (MTS) representation learning aims to extract compact and informative representations from raw sequences without relying on labels, enabling efficient transfer to diverse downstream tasks. In this…

Machine Learning · Computer Science 2025-09-22 Yi Xu , Yitian Zhang , Yun Fu

Nonlinear Mixed Effects models (NLME) models are widely used in pharmacometrics and related fields to analyze hierarchical and longitudinal data. However, as the number of parameters and random effects increases, traditional methods for…

Methodology · Statistics 2026-04-30 Mohamed Tarek , Pedro Afonso

Variational Autoencoders (VAEs), as a form of deep generative model, have been widely used in recent years, and shown great great peformance in a number of different domains, including image generation and anomaly detection, etc.. This…

Machine Learning · Computer Science 2024-08-28 Liang Cheng , Peiyuan Guan , Amir Taherkordi , Lei Liu , Dapeng Lan

Recent work in synthetic data generation in the time-series domain has focused on the use of Generative Adversarial Networks. We propose a novel architecture for synthetically generating time-series data with the use of Variational…

Machine Learning · Computer Science 2021-12-08 Abhyuday Desai , Cynthia Freeman , Zuhui Wang , Ian Beaver

Variational autoencoders (VAEs) defined over SMILES string and graph-based representations of molecules promise to improve the optimization of molecular properties, thereby revolutionizing the pharmaceuticals and materials industries.…

Machine Learning · Computer Science 2019-06-04 Zaccary Alperstein , Artem Cherkasov , Jason Tyler Rolfe

Quantitative imaging methods, such as magnetic resonance fingerprinting (MRF), aim to extract interpretable pathology biomarkers by estimating biophysical tissue parameters from signal evolutions. However, the pattern-matching algorithms or…

In the contrastive analysis (CA) setting, machine learning practitioners are specifically interested in discovering patterns that are enriched in a target dataset as compared to a background dataset generated from sources of variation…

Machine Learning · Computer Science 2022-02-23 Ethan Weinberger , Nicasia Beebe-Wang , Su-In Lee

Variational autoencoder (VAE) is one of the most common techniques in the field of medical image generation, where this architecture has shown advanced researchers in recent years and has developed into various architectures. VAE has…

Machine Learning · Computer Science 2024-11-13 Khadija Rais , Mohamed Amroune , Abdelmadjid Benmachiche , Mohamed Yassine Haouam

Optimization of rotating electrical machines is both time- and computationally expensive. Because of the different parametrization, design optimization is commonly executed separately for each machine technology. In this paper, we present…

Machine Learning · Computer Science 2023-08-25 Vivek Parekh , Dominik Flore , Sebastian Schöps

Directed evolution as a widely-used engineering strategy faces obstacles in finding desired mutants from the massive size of candidate modifications. While deep learning methods learn protein contexts to establish feasible searching space,…

Quantitative Methods · Quantitative Biology 2023-04-18 Bingxin Zhou , Outongyi Lv , Kai Yi , Xinye Xiong , Pan Tan , Liang Hong , Yu Guang Wang

We address the challenge of training Vision Transformers (ViTs) when labeled data is scarce but unlabeled data is abundant. We propose Semi-Supervised Masked Autoencoder (SSMAE), a framework that jointly optimizes masked image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Atik Faysal , Mohammad Rostami , Reihaneh Gh. Roshan , Nikhil Muralidhar , Huaxia Wang

Pre-training video transformers on extra large-scale datasets is generally required to achieve premier performance on relatively small datasets. In this paper, we show that video masked autoencoders (VideoMAE) are data-efficient learners…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Zhan Tong , Yibing Song , Jue Wang , Limin Wang

Variational autoencoders (VAEs) are powerful generative models with the salient ability to perform inference. Here, we introduce a quantum variational autoencoder (QVAE): a VAE whose latent generative process is implemented as a quantum…

The Vision Transformer (ViT) has demonstrated remarkable performance in Self-Supervised Learning (SSL) for 3D medical image analysis. Masked AutoEncoder (MAE) for feature pre-training can further unleash the potential of ViT on various…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Jiaxin Zhuang , Linshan Wu , Qiong Wang , Peng Fei , Varut Vardhanabhuti , Lin Luo , Hao Chen

Pulse-shape discrimination (PSD) in high-purity germanium (HPGe) detectors is central to rare-event searches such as neutrinoless double-beta decay (0vBB), yet conventional approaches compress each waveform into a small set of summary…

High Energy Physics - Experiment · Physics 2026-03-09 Marta Babicz , Saúl Alonso-Monsalve , Alain Fauquex , Laura Baudis

Variational autoencoders (VAEs) are powerful tools for learning latent representations of data used in a wide range of applications. In practice, VAEs usually require multiple training rounds to choose the amount of information the latent…

Machine Learning · Computer Science 2023-08-21 Juhan Bae , Michael R. Zhang , Michael Ruan , Eric Wang , So Hasegawa , Jimmy Ba , Roger Grosse

This study investigates the use of non-linear unsupervised dimensionality reduction techniques to compress a music dataset into a low-dimensional representation which can be used in turn for the synthesis of new sounds. We systematically…

Audio and Speech Processing · Electrical Eng. & Systems 2019-05-27 Fanny Roche , Thomas Hueber , Samuel Limier , Laurent Girin

Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken
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