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Sample size calculations for power analysis are critical for clinical research and trial design, yet their complexity and reliance on statistical expertise create barriers for many researchers. We introduce PowerGPT, an AI-powered system…

Large Language Models (LLMs) have shown remarkable effectiveness in various general-domain natural language processing (NLP) tasks. However, their performance in transportation safety domain tasks has been suboptimal, primarily attributed…

Computation and Language · Computer Science 2023-07-31 Ou Zheng , Mohamed Abdel-Aty , Dongdong Wang , Chenzhu Wang , Shengxuan Ding

Large language models (LLMs) are establishing new paradigms for engineering applications by enabling natural language control of complex computational workflows. This paper introduces FeaGPT, the first framework to achieve complete…

Software Engineering · Computer Science 2025-10-28 Yupeng Qi , Ran Xu , Xu Chu

Language models such as GPT and Llama have shown remarkable ability on diverse natural language tasks, yet their performance on complex table tasks (e.g., NL-to-Code and data cleaning) remains suboptimal. Improving performance typically…

Computation and Language · Computer Science 2026-03-25 Junjie Xing , Yeye He , Mengyu Zhou , Haoyu Dong , Shi Han , Dongmei Zhang , Surajit Chaudhuri

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Clinical trials are an integral component of medical research. Trials require careful design to, for example, maintain the safety of participants, use resources efficiently and allow clinically meaningful conclusions to be drawn. Adaptive…

Methodology · Statistics 2025-07-17 James M. McGree , Antony M. Overstall , Mark Jones , Robert K. Mahar

Recent advances in Large Language Models (LLMs) have presented new opportunities for integrating Artificial General Intelligence (AGI) into biological research and education. This study evaluated the capabilities of leading LLMs, including…

Computation and Language · Computer Science 2023-11-15 Xinyu Gong , Jason Holmes , Yiwei Li , Zhengliang Liu , Qi Gan , Zihao Wu , Jianli Zhang , Yusong Zou , Yuxi Teng , Tian Jiang , Hongtu Zhu , Wei Liu , Tianming Liu , Yajun Yan

Large Language Models (LLMs), including the LLaMA model, have exhibited their efficacy across various general-domain natural language processing (NLP) tasks. However, their performance in high-performance computing (HPC) domain tasks has…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-11-23 Xianzhong Ding , Le Chen , Murali Emani , Chunhua Liao , Pei-Hung Lin , Tristan Vanderbruggen , Zhen Xie , Alberto E. Cerpa , Wan Du

Large language models (LLMs) such as ChatGPT have gained considerable interest across diverse research communities. Their notable ability for text completion and generation has inaugurated a novel paradigm for language-interfaced problem…

Quantitative Methods · Quantitative Biology 2024-02-22 Hengchuang Yin , Zhonghui Gu , Fanhao Wang , Yiparemu Abuduhaibaier , Yanqiao Zhu , Xinming Tu , Xian-Sheng Hua , Xiao Luo , Yizhou Sun

Artificial intelligence (AI) methods have become critical in scientific applications to help accelerate scientific discovery. Large language models (LLMs) are being considered as a promising approach to address some of the challenging…

Generative artificial intelligence (AI) and large language models (LLMs) have gained rapid popularity through publicly available tools such as ChatGPT. The adoption of LLMs for personal and professional use is fueled by the natural…

Computation and Language · Computer Science 2024-07-25 Sinan Abdulhak , Wayne Hubbard , Karthik Gopalakrishnan , Max Z. Li

The integration of Large Language Models (LLMs) with evolutionary computation (EC) has introduced a promising paradigm for automating the design of metaheuristic algorithms. However, existing frameworks, such as the Large Language Model…

Neural and Evolutionary Computing · Computer Science 2024-12-05 Haoran Yin , Anna V. Kononova , Thomas Bäck , Niki van Stein

Artificial intelligence (AI) researchers have been developing and refining large language models (LLMs) that exhibit remarkable capabilities across a variety of domains and tasks, challenging our understanding of learning and cognition. The…

The rising popularity of large language models (LLMs) has raised concerns about machine-generated text (MGT), particularly in academic settings, where issues like plagiarism and misinformation are prevalent. As a result, developing a highly…

Artificial Intelligence · Computer Science 2025-08-05 Yule Liu , Zhiyuan Zhong , Yifan Liao , Zhen Sun , Jingyi Zheng , Jiaheng Wei , Qingyuan Gong , Fenghua Tong , Yang Chen , Yang Zhang , Xinlei He

There is growing interest in using machine learning (ML) to support clinical diagnosis, but most approaches rely on static, fully observed datasets and fail to reflect the sequential, resource-aware reasoning clinicians use in practice.…

Artificial Intelligence · Computer Science 2025-11-18 Silas Ruhrberg Estévez , Nicolás Astorga , Mihaela van der Schaar

Language models (LMs) pretrained on a large text corpus and fine-tuned on a downstream text corpus and fine-tuned on a downstream task becomes a de facto training strategy for several natural language processing (NLP) tasks. Recently, an…

Computation and Language · Computer Science 2021-07-23 Junghoon Lee , Jounghee Kim , Pilsung Kang

Empathetic dialogue is an indispensable part of building harmonious social relationships and contributes to the development of a helpful AI. Previous approaches are mainly based on fine small-scale language models. With the advent of…

Computation and Language · Computer Science 2024-07-29 Yushan Qian , Wei-Nan Zhang , Ting Liu

Vision-language models (VLMs) such as CLIP achieve strong zero-shot recognition but degrade significantly under \textit{temporally evolving distribution shifts} common in real-world scenarios (e.g., gradual illumination or seasonal…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Shuang Cui , Jinglin Xu , Yi Li , Xiongxin Tang , Jiangmeng Li , Jiahuan Zhou , Fanjiang Xu , Fuchun Sun , Hui Xiong

Recent advancements in large language models (LLMs) like ChatGPT and LLaMA show promise in medical applications, yet challenges remain in medical language comprehension. This study presents Me-LLaMA, a new medical LLM family based on…

As algorithmic decision-makers are increasingly applied to high-stakes domains, AI alignment research has evolved from a focus on universal value alignment to context-specific approaches that account for decision-maker attributes. Prior…