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Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25…

Deformable image registration (DIR) is an enabling technology in many diagnostic and therapeutic tasks. Despite this, DIR algorithms have limited clinical use, largely due to a lack of benchmark datasets for quality assurance during…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Edward R Criscuolo , Yao Hao , Zhendong Zhang , Trevor McKeown , Deshan Yang

Deformable image registration (DIR) is a crucial tool in radiotherapy for analyzing anatomical changes and motion patterns. Current DIR implementations rely on discrete volumetric motion representation, which often leads to compromised…

Medical Physics · Physics 2025-07-22 Xia Li , Runzhao Yang , Muheng Li , Xiangtai Li , Antony J. Lomax , Joachim M. Buhmann , Ye Zhang

Purpose: Evaluating deformable image registration (DIR) algorithms is vital for enhancing algorithm performance and gaining clinical acceptance. However, there's a notable lack of dependable DIR benchmark datasets for assessing DIR…

Medical Physics · Physics 2024-04-09 Zhendong Zhang , Edward Robert Criscuolo , Yao Hao , Deshan Yang

Deformable Image Registration (DIR) is essential for aligning medical images that exhibit anatomical variations, facilitating applications such as disease tracking and radiotherapy planning. While classical iterative methods and deep…

Computer Vision and Pattern Recognition · Computer Science 2025-09-08 Jihe Li , Xiang Liu , Fabian Zhang , Xia Li , Xixin Cao , Ye Zhang , Joachim Buhmann

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Medical Physics · Physics 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

Anatomical motion and deformation pose challenges to the understanding of the delivered dose distribution during radiotherapy treatments. Hence, deformable image registration (DIR) algorithms are increasingly used to map contours and dose…

Medical Physics · Physics 2021-09-22 Emily Cloutier , Luc Beaulieu , Louis Archambault

Online adaptive radiation therapy (ART) promises the ability to deliver an optimal treatment in response to daily patient anatomic variation. A major technical barrier for the clinical implementation of online ART is the requirement of…

Background and Objective: Precise preoperative planning and effective physician training for coronary interventions are increasingly important. Despite advances in medical imaging technologies, transforming static or limited dynamic imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Shuo Wang , Tong Ren , Nan Cheng , Rong Wang , Li Zhang

This paper aims to create a deep learning framework that can estimate the deformation vector field (DVF) for directly registering abdominal MRI-CT images. The proposed method assumed a diffeomorphic deformation. By using topology-preserved…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Yang Lei , Luke A. Matkovic , Justin Roper , Tonghe Wang , Jun Zhou , Beth Ghavidel , Mark McDonald , Pretesh Patel , Xiaofeng Yang

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Zhe Xu , Jie Luo , Jiangpeng Yan , Xiu Li , Jagadeesan Jayender

Cardiac digital twins are computational tools capturing key functional and anatomical characteristics of patient hearts for investigating disease phenotypes and predicting responses to therapy. When paired with large-scale computational…

Computational Engineering, Finance, and Science · Computer Science 2024-01-19 Julia Camps , Zhinuo Jenny Wang , Ruben Doste , Maxx Holmes , Brodie Lawson , Jakub Tomek , Kevin Burrage , Alfonso Bueno-Orovio , Blanca Rodriguez

This work aims to generate realistic anatomical deformations from static patient scans. Specifically, we present a method to generate these deformations/augmentations via deep learning driven respiratory motion simulation that provides the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-30 Donghoon Lee , Ellen Yorke , Masoud Zarepisheh , Saad Nadeem , Yu-Chi Hu

When choosing a deformable image registration (DIR) approach for images with large deformations and content mismatch, the realism of found transformations often needs to be traded off against the required runtime. DIR approaches using deep…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Georgios Andreadis , Eduard Ruiz Munné , Thomas H. W. Bäck , Peter A. N. Bosman , Tanja Alderliesten

Background and Purpose: Voxel-based analysis (VBA) helps to identify dose-sensitive regions by aligning individual dose distributions within a common coordinate system (CCS). Accurate deformable image registration (DIR) is essential for…

Medical Physics · Physics 2025-09-26 Xingyue Ruan , Xia Li , Muheng Li , Barbara Bachtiary , Antony Lomax , Zhiling Chen , Ye Zhang

Deformable image registration (DIR) involves optimization of multiple conflicting objectives, however, not many existing DIR algorithms are multi-objective (MO). Further, while there has been progress in the design of deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Monika Grewal , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

Digital Twins technology is revolutionizing decision-making in scientific research by integrating models and simulations with real-time data. Unlike traditional Structural Health Monitoring methods, which rely on computationally intensive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Mehrdad Shafiei Dizaji

Dynamic MRI may capture temporal anatomical changes in soft tissue organs with high contrast but the obtained sequences usually suffer from limited volume coverage which makes the high resolution reconstruction of organ shape trajectories a…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Karim Makki , Amine Bohi , Augustin . C Ogier , Marc Emmanuel Bellemare

Objective: In medical imaging, it is often crucial to accurately assess and correct movement during image-guided therapy. Deformable image registration (DIR) consists in estimating the required spatial transformation to align a moving image…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Eloïse Inacio , Luc Lafitte , Laurent Facq , Clair Poignard , Baudouin Denis de Senneville
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