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As motivated by studies of cellular motility driven by spatiotemporal chemotactic gradients in microdevices, we develop a framework for constructing approximate analytical solutions for the location, speed and cellular densities for cell…

Analysis of PDEs · Mathematics 2022-11-09 Jacobo Ayensa-Jiménez , Mohamed H. Doweidar , Manuel Doblaré , Eamonn A. Gaffney

Photosynthesis is vital for the survival of entire ecosystems on Earth. While light is fundamental to this process, excessive exposure can be detrimental to plant cells. Chloroplasts, the photosynthetic organelles, actively move in response…

Soft Condensed Matter · Physics 2025-01-27 Nico Schramma , Eric R. Weeks , Maziyar Jalaal

One of the most ancient forms of life dating to ~3.5 billion years ago, cyanobacteria are highly abundant organisms that convert light into energy and motion, often within conjoined filaments and larger colonies. We study how gradients of…

Soft Condensed Matter · Physics 2023-10-03 Andrii Repula , Colin Gates , Jeffrey C. Cameron , Ivan I. Smalyukh

Active turbulence arises typically in systems ranging from microorganisms and biopolymers to synthetic colloids, where chaotic flows are closely associated with motile topological defects in collectively swarming suspensions. Here, we…

Soft Condensed Matter · Physics 2026-04-27 Prince Vibek Baruah , Nadia Bihari Padhan , Biswajit Maji , Rahul Pandit , Prerna Sharma

Many motile microorganisms react to environmental light cues with a variety of motility responses guiding cells towards better conditions for survival and growth. The use of spatial light modulators could help to elucidate the mechanisms of…

Many motile biological cells navigate along concentration gradients of signaling molecules: This chemotaxis guides for instance sperm cells from marine invertebrates, which have to find egg cells in the ocean. While chemotaxis has been…

Biological Physics · Physics 2022-09-21 Steffen Lange , Benjamin M. Friedrich

Despite evidence for a hydrodynamic origin of flagellar synchronization between different eukaryotic cells, recent experiments have shown that in single multi-flagellated organisms, coordination hinges instead on direct basal body…

Biological Physics · Physics 2018-10-12 Yujie Liu , Rory Claydon , Marco Polin , Douglas R. Brumley

We experimentally investigate the role of illumination on the collective dynamics of a large school (ca. 50 individuals) of Hemigrammus rhodostomus. The structure of the group, defined using two order parameters, is quantified while…

Adaptation and Self-Organizing Systems · Physics 2023-01-24 Baptiste Lafoux , Jeanne Moscatelli , Ramiro Godoy-Diana , Benjamin Thiria

We discuss recent progress in the theoretical description of chemotaxis by coupling the diffusion equation of a chemical species to equations describing the motion of sensing microorganisms. In particular, we discuss models for…

Soft Condensed Matter · Physics 2019-02-05 B. Liebchen , H. Löwen

Aerotaxis is the particular form of chemotaxis in which oxygen plays the role of both the attractant and the repellent. Aerotaxis occurs without methylation adaptation, and it leads to fast and complete aggregation toward the most favorable…

Classical Analysis and ODEs · Mathematics 2015-06-26 Barbara "Bori" C. Mazzag

Many animal cells change their shape depending on the stiffness of the substrate on which they are cultured: they assume small, rounded shapes in soft ECMs, they elongate within stiffer ECMs, and flatten out on hard substrates. Cells tend…

Cell Behavior · Quantitative Biology 2019-06-24 Elisabeth G. Rens , Roeland M. H. Merks

The prevalence of multicellular organisms is due in part to their ability to form complex structures. How cells pack in these structures is a fundamental biophysical issue, underlying their functional properties. However, much remains…

The persistent motility of the individual constituents in microbial suspensions represents a prime example of so-called active matter systems. Cells consume energy, exert forces and move, overall releasing the constraints of equilibrium…

Biological Physics · Physics 2020-11-02 Armand Javadi , Jorge Arrieta , Idan Tuval , Marco Polin

Phagocytosis is the process by which cells, which are 5 to 10 times larger than the particle size, engulf particles, holding substantial importance in various biological contexts ranging from the nutrient uptake of unicellular organisms to…

Soft Condensed Matter · Physics 2024-11-20 Partha Sarathi Mondal , Pawan Kumar Mishra , Mitali Thorat , Ananya Verma , Shradha Mishra

We present a simple model that describes the motion of a single chemotactic cell exposed to a traveling wave of the chemoattractant. The model incorporates two types of responses to stimulation by the chemoattractant, i.e., change in…

Biological Physics · Physics 2011-10-26 Masatomo Iwasa , Ryosuke Ishiwata

One approach to quantifying biological diversity consists of characterizing the statistical distribution of specific properties of a taxonomic group or habitat. Microorganisms living in fluid environments, and for whom motility is key,…

Soft Condensed Matter · Physics 2020-12-03 Maciej Lisicki , Marcos F. Velho Rodrigues , Raymond E. Goldstein , Eric Lauga

Living creatures exhibit a remarkable diversity of locomotion mechanisms, evolving structures specialised for interacting with their environment. In the vast majority of cases, locomotor behaviours such as flying, crawling, and running, are…

Biological Physics · Physics 2020-07-28 Kirsty Y. Wan

Observations of single epidermal cells on flat adhesive substrates have revealed two distinct morphological and functional states, namely a non-migrating symmetric unpolarized state and a migrating asymmetric polarized state. These states…

Biological Physics · Physics 2010-04-14 Wolfgang Alt , Martin Bock , Christoph Möhl

Motivated by observations of the dynamics of {\it Myxococcus xanthus}, we present a self-interacting random walk model that describes the competition between chemokinesis and chemotaxis. Cells are constrained to move in one dimension, but…

Statistical Mechanics · Physics 2016-08-31 Maria R. D'Orsogna , Marc Suchard , Tom Chou

Large ensembles of interacting, out-of-equilibrium agents are a paradigm of active matter. Their constituents' intrinsic activity may entail the spontaneous separation into localized phases of high and low densities. Motile microbes,…

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