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Mammography and ultrasound are extensively used by radiologists as complementary modalities to achieve better performance in breast cancer diagnosis. However, existing computer-aided diagnosis (CAD) systems for the breast are generally…

Image and Video Processing · Electrical Eng. & Systems 2020-09-24 Gavriel Habib , Nahum Kiryati , Miri Sklair-Levy , Anat Shalmon , Osnat Halshtok Neiman , Renata Faermann Weidenfeld , Yael Yagil , Eli Konen , Arnaldo Mayer

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Self-supervised pretraining followed by supervised fine-tuning has seen success in image recognition, especially when labeled examples are scarce, but has received limited attention in medical image analysis. This paper studies the…

The accurate evaluation of left atrial fibrosis via high-quality 3D Late Gadolinium Enhancement (LGE) MRI is crucial for atrial fibrillation management but is hindered by factors like patient movement and imaging variability. The pursuit of…

Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

Multiple Instance Learning (MIL) methods have become increasingly popular for classifying giga-pixel sized Whole-Slide Images (WSIs) in digital pathology. Most MIL methods operate at a single WSI magnification, by processing all the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Kevin Thandiackal , Boqi Chen , Pushpak Pati , Guillaume Jaume , Drew F. K. Williamson , Maria Gabrani , Orcun Goksel

Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Junjian Li , Jin Liu , Hulin Kuang , Hailin Yue , Mengshen He , Jianxin Wang

Reliable artificial intelligence (AI) models for medical image analysis often depend on large and diverse labeled datasets. Federated learning (FL) offers a decentralized and privacy-preserving approach to training but struggles in highly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Mahshad Lotfinia , Arash Tayebiarasteh , Samaneh Samiei , Mehdi Joodaki , Soroosh Tayebi Arasteh

A high-risk pregnancy is a pregnancy complicated by factors that can adversely affect the outcomes of the mother or the infant. Health insurers use algorithms to identify members who would benefit from additional clinical support. This work…

Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label…

Computer Vision and Pattern Recognition · Computer Science 2019-06-28 Meng Li , Lin Wu , Arnold Wiliem , Kun Zhao , Teng Zhang , Brian C. Lovell

In the application of Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) classification, attention mechanisms often focus on a subset of discriminative instances, which are closely linked to overfitting. To mitigate…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yunlong Zhang , Honglin Li , Yuxuan Sun , Sunyi Zheng , Chenglu Zhu , Lin Yang

Whole Slide Images (WSI), obtained by high-resolution digital scanning of microscope slides at multiple scales, are the cornerstone of modern Digital Pathology. However, they represent a particular challenge to AI-based/AI-mediated analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Martim Afonso , Praphulla M. S. Bhawsar , Monjoy Saha , Jonas S. Almeida , Arlindo L. Oliveira

Multiple Instance Learning (MIL) has been widely used in weakly supervised whole slide image (WSI) classification. Typical MIL methods include a feature embedding part, which embeds the instances into features via a pre-trained feature…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Peijie Qiu , Pan Xiao , Wenhui Zhu , Yalin Wang , Aristeidis Sotiras

Ultrasound is the primary imaging modality in clinical practice during pregnancy. More than 140M fetuses are born yearly, resulting in numerous scans. The availability of a large volume of fetal ultrasound scans presents the opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Hussain Alasmawi , Leanne Bricker , Mohammad Yaqub

Multiple instance learning (MIL) has been widely used for representing whole-slide pathology images. However, spatial, semantic, and decision entanglements among instances limit its representation and interpretability. To address these…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Chentao Li , Behzad Bozorgtabar , Yifang Ping , Pan Huang , Jing Qin

Recently, self-supervised instance discrimination methods have achieved significant success in learning visual representations from unlabeled photographic images. However, given the marked differences between photographic and medical…

Image and Video Processing · Electrical Eng. & Systems 2022-04-18 Mohammad Reza Hosseinzadeh Taher , Fatemeh Haghighi , Michael B. Gotway , Jianming Liang

Learning accurate object detectors often requires large-scale training data with precise object bounding boxes. However, labeling such data is expensive and time-consuming. As the crowd-sourcing labeling process and the ambiguities of the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Chengxin Liu , Kewei Wang , Hao Lu , Zhiguo Cao , Ziming Zhang

Fetal ultrasound standard plane classification is essential for reliable prenatal diagnosis but faces inherent challenges, including low tissue contrast, boundary ambiguity, and operator-dependent image quality variations. To overcome these…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Yang Chen , Sanglin Zhao , Baoyu Chen , Mans Gustaf

Automatic segmentation of the placenta in fetal ultrasound (US) is challenging due to the (i) high diversity of placenta appearance, (ii) the restricted quality in US resulting in highly variable reference annotations, and (iii) the limited…

Trauma is a significant cause of mortality and disability, particularly among individuals under forty. Traditional diagnostic methods for traumatic injuries, such as X-rays, CT scans, and MRI, are often time-consuming and dependent on…

Image and Video Processing · Electrical Eng. & Systems 2024-07-24 Liheng Jiang , Xuechun yang , Chang Yu , Zhizhong Wu , Yuting Wang