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Local hemodynamic forces play an important role in determining the functional significance of coronary arterial stenosis and understanding the mechanism of coronary disease progression. Computational fluid dynamics (CFD) have been widely…

While contrast-enhanced CT (CECT) is standard for assessing abdominal aortic aneurysms (AAA), the required iodinated contrast agents pose significant risks, including nephrotoxicity, patient allergies, and environmental harm. To reduce…

Simulating facial appearance change following bony movement is a critical step in orthognathic surgical planning for patients with jaw deformities. Conventional biomechanics-based methods such as the finite-element method (FEM) are labor…

Purpose: To evaluate deep learning (DL) models for enhancing vitreous optical coherence tomography (OCT) image quality and reducing acquisition time. Methods: Conditional Denoising Diffusion Probabilistic Models (cDDPMs), Brownian Bridge…

The increasing reliance on Computed Tomography Pulmonary Angiography (CTPA) for Pulmonary Embolism (PE) diagnosis presents challenges and a pressing need for improved diagnostic solutions. The primary objective of this study is to leverage…

Anatomical and biophysical modeling of left atrium (LA) and proximal pulmonary veins (PPVs) is important for clinical management of several cardiac diseases. Magnetic resonance imaging (MRI) allows qualitative assessment of LA and PPVs…

The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies…

Modern machine learning pipelines, in particular those based on deep learning (DL) models, require large amounts of labeled data. For classification problems, the most common learning paradigm consists of presenting labeled examples during…

Deep learning approaches may help radiologists in the early diagnosis and timely treatment of cerebrovascular diseases. Accurate cerebral vessel segmentation of Time-of-Flight Magnetic Resonance Angiographs (TOF-MRAs) is an essential step…

Quantification of myocardial perfusion has the potential to improve detection of regional and global flow reduction. Significant effort has been made to automate the workflow, where one essential step is the arterial input function (AIF)…

This study leverages convolutional neural networks to enhance the temporal resolution of 3D angiography in intracranial aneurysms focusing on the reconstruction of volumetric contrast data from sparse and limited projections. Three…

Purpose: To develop and evaluate a semi-supervised learning model for intracranial hemorrhage detection and segmentation on an out-of-distribution head CT evaluation set. Materials and Methods: This retrospective study used semi-supervised…

Pre-operative Abdominal Aortic Aneurysm (AAA) 3D shape is critical for customized stent-graft design in Fenestrated Endovascular Aortic Repair (FEVAR). Traditional segmentation approaches implement expert-designed feature extractors while…

Deep learning approaches have achieved state-of-the-art performance in cardiac magnetic resonance (CMR) image segmentation. However, most approaches have focused on learning image intensity features for segmentation, whereas the…

As the first diagnostic imaging modality of avascular necrosis of the femoral head (AVNFH), accurately staging AVNFH from a plain radiograph is critical yet challenging for orthopedists. Thus, we propose a deep learning-based AVNFH…

Segmentation of medical images is a fundamental task with numerous applications. While MRI, CT, and PET modalities have significantly benefited from deep learning segmentation techniques, more recent modalities, like functional ultrasound…

Head computed tomography (CT) imaging is a widely-used imaging modality with multitudes of medical indications, particularly in assessing pathology of the brain, skull, and cerebrovascular system. It is commonly the first-line imaging in…

Convolutional neural networks (CNN) for multi-class segmentation of medical images are widely used today. Especially models with multiple outputs that can separately predict segmentation classes (regions) without relying on a probabilistic…

Whole-body CT is used for multi-trauma patients in the search of any and all injuries. Since an initial assessment needs to be rapid and the search for lesions is done for the whole body, very little time can be allocated for the inspection…

Automated segmentation of intracranial arteries on magnetic resonance angiography (MRA) allows for quantification of cerebrovascular features, which provides tools for understanding aging and pathophysiological adaptations of the…