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We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Deformable medical image registration aligns anatomical structures across images but remains computationally dense at 3D resolution. Spiking neural networks (SNNs) offer sparse event-driven computation, yet have not been systematically…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Ali Mikaeili Barzili , Behzad Moshiri , Hamid Azadegan , Mohammad-Reza A. Dehaqani

The unrolling method has been investigated for learning variational models in X-ray computed tomography. However, it has been observed that directly unrolling the regularization model through gradient descent does not produce satisfactory…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Yijie Yang , Qifeng Gao , Yuping Duan

Machine unlearning aims to remove the influence of specific training samples from a trained model without full retraining. While prior work has largely focused on privacy-motivated settings, we recast unlearning as a general-purpose tool…

Image and Video Processing · Electrical Eng. & Systems 2026-02-11 George R. Nahass , Zhu Wang , Homa Rashidisabet , Won Hwa Kim , Sasha Hubschman , Jeffrey C. Peterson , Chad A. Purnell , Pete Setabutr , Ann Q. Tran , Darvin Yi , Sathya N. Ravi

For computational efficiency, surrogate models have been used to emulate mathematical simulators for physical or biological processes. High-speed simulation is crucial for conducting uncertainty quantification (UQ) when the simulation is…

Machine Learning · Computer Science 2022-11-21 Lixiang Zhang , Jia Li

Explainability of deep neural networks is one of the most challenging and interesting problems in the field. In this study, we investigate the topic focusing on the interpretability of deep learning-based registration methods. In…

Unrolled neural networks have recently achieved state-of-the-art accelerated MRI reconstruction. These networks unroll iterative optimization algorithms by alternating between physics-based consistency and neural-network based…

Image and Video Processing · Electrical Eng. & Systems 2022-07-19 Batu Ozturkler , Arda Sahiner , Tolga Ergen , Arjun D Desai , Christopher M Sandino , Shreyas Vasanawala , John M Pauly , Morteza Mardani , Mert Pilanci

Deformable registration is crucial in medical imaging. Several existing applications include lesion tracking, probabilistic atlas generation, and treatment response evaluation. However, current methods often lack robustness and…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Yunzheng Zhu , Aichi Chien , Kimaya kulkarni , Luoting Zhuang , Stephen Park , Ricky Savjani , Daniel Low , William Hsu

In recent years, large convolutional neural networks have been widely used as tools for image deblurring, because of their ability in restoring images very precisely. It is well known that image deblurring is mathematically modeled as an…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Davide Evangelista , Elena Morotti , Elena Loli Piccolomini , James Nagy

Data assisted reconstruction algorithms, incorporating trained neural networks, are a novel paradigm for solving inverse problems. One approach is to first apply a classical reconstruction method and then apply a neural network to improve…

Numerical Analysis · Mathematics 2020-03-26 Yoeri E. Boink , Markus Haltmeier , Sean Holman , Johannes Schwab

Deep equilibrium networks (DEQs) are a new class of models that eschews traditional depth in favor of finding the fixed point of a single nonlinear layer. These models have been shown to achieve performance competitive with the…

Machine Learning · Computer Science 2021-06-29 Shaojie Bai , Vladlen Koltun , J. Zico Kolter

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

Deformable image registration between Computed Tomography (CT) images and Magnetic Resonance (MR) imaging is essential for many image-guided therapies. In this paper, we propose a novel translation-based unsupervised deformable image…

Image and Video Processing · Electrical Eng. & Systems 2020-09-22 Zhe Xu , Jie Luo , Jiangpeng Yan , Ritvik Pulya , Xiu Li , William Wells , Jayender Jagadeesan

Optimization-based solvers play a central role in a wide range of signal processing and communication tasks. However, their applicability in latency-sensitive systems is limited by the sequential nature of iterative methods and the high…

Signal Processing · Electrical Eng. & Systems 2026-03-12 Dvir Avrahami , Amit Milstein , Caroline Chaux , Tirza Routtenberg , Nir Shlezinger

Recently, deep unfolding methods that guide the design of deep neural networks (DNNs) through iterative algorithms have received increasing attention in the field of inverse problems. Unlike general end-to-end DNNs, unfolding methods have…

Optimization and Control · Mathematics 2022-11-28 Zhuo-Xu Cui , Qingyong Zhu , Jing Cheng , Dong Liang

Deep equilibrium models (DEQs) have proven to be very powerful for learning data representations. The idea is to replace traditional (explicit) feedforward neural networks with an implicit fixed-point equation, which allows to decouple the…

Machine Learning · Computer Science 2023-04-25 Bac Nguyen , Lukas Mauch

Objective: Deep learning-based deformable image registration has achieved strong accuracy, but remains sensitive to variations in input image characteristics such as artifacts, field-of-view mismatch, or modality difference. We aim to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yihao Liu , Junyu Chen , Lianrui Zuo , Shuwen Wei , Brian D. Boyd , Carmen Andreescu , Olusola Ajilore , Warren D. Taylor , Aaron Carass , Bennett A. Landman

In this paper we consider the problem of learning variational models in the context of supervised learning via risk minimization. Our goal is to provide a deeper understanding of the two approaches of learning of variational models via…

Machine Learning · Statistics 2023-09-07 Christoph Brauer , Niklas Breustedt , Timo de Wolff , Dirk A. Lorenz

Deep equilibrium (DEQ) models replace the multiple-layer stacking of conventional deep networks with a fixed-point iteration of a single-layer transformation. Having been demonstrated to be competitive in a variety of real-world scenarios,…

Machine Learning · Computer Science 2023-06-05 Zonghan Yang , Peng Li , Tianyu Pang , Yang Liu

Deep Equilibrium Model (DEQ), which serves as a typical implicit neural network, emphasizes their memory efficiency and competitive performance compared to explicit neural networks. However, there has been relatively limited theoretical…

Machine Learning · Computer Science 2024-12-05 Haixiang Sun , Ye Shi
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