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The reconstruction of dynamic positron emission tomography (PET) images from noisy projection data is a significant but challenging problem. In this paper, we introduce an unsupervised learning approach, Non-negative Implicit Neural…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Chaozhi Zhang , Wenxiang Ding , Roy Y. He , Xiaoqun Zhang , Qiaoqiao Ding

Image reconstruction for positron emission tomography (PET) is challenging because of the ill-conditioned tomographic problem and low counting statistics. Kernel methods address this challenge by using kernel representation to incorporate…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Siqi Li , Guobao Wang

Image reconstruction of low-count positron emission tomography (PET) data is challenging. Kernel methods address the challenge by incorporating image prior information in the forward model of iterative PET image reconstruction. The…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Siqi Li , Kuang Gong , Ramsey D. Badawi , Edward J. Kim , Jinyi Qi , Guobao Wang

We develop and evaluate MlPET, a fast localized machine learning approach for probabilistic PET image analysis addressing the noise-resolution trade-off in conventional reconstructions. MlPET replaces computationally demanding Markov chain…

Medical Physics · Physics 2026-01-27 Thomas Mejer Hansen , Nana Christensen , Mikkel Vendelbo

Dynamic positron emission tomography (PET) reconstruction often presents high noise due to the use of short duration frames to describe the kinetics of the radiotracer. Here we introduce a new method to calculate a kernel matrix to be used…

Medical Physics · Physics 2026-01-01 Alan Miranda , Steven Staelens

Low-dose positron emission tomography (PET) image reconstruction methods have potential to significantly improve PET as an imaging modality. Deep learning provides a promising means of incorporating prior information into the image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Cameron Dennis Pain , Yasmeen George , Alex Fornito , Gary Egan , Zhaolin Chen

Purpose: To develop a fast, general-purpose framework for voxelwise noise characterization in linear and nonlinear iterative MRI reconstructions, recovering the image-domain noise variance from which SNR, $g$-factor, and related…

Signal Processing · Electrical Eng. & Systems 2026-05-12 Onat Dalmaz , Daniel Abraham , Alexander R. Toews , Akshay S. Chaudhari , Kawin Setsompop , Brian A. Hargreaves

The nonnegative matrix factorization (NMF) is widely used in signal and image processing, including bio-informatics, blind source separation and hyperspectral image analysis in remote sensing. A great challenge arises when dealing with a…

Computer Vision and Pattern Recognition · Computer Science 2016-03-29 Fei Zhu , Paul Honeine , Maya Kallas

Single-bed whole-body positron emission tomography based on resistive plate chamber detectors (RPC-PET) has been proposed for human studies, as a complementary resource to scintillator-based PET scanners. The purpose of this work is mainly…

Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Jieqing Jiao , Sebastien Ourselin

One of the main computational bottlenecks when working with kernel based learning is dealing with the large and typically dense kernel matrix. Techniques dealing with fast approximations of the matrix vector product for these kernel…

Machine Learning · Computer Science 2024-04-29 Theresa Wagner , Franziska Nestler , Martin Stoll

Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

Dynamic PET kinetic modeling increasingly demands voxelwise uncertainty quantification and robust model selection. Yet total-body PET (TB-PET) data volumes make conventional Bayesian approaches, such as per-voxel MCMC, computationally…

Applications · Statistics 2026-03-17 Qinlin Gu , Gaelle M. Emvalomenos , Evan D. Morris , Clara Grazian , Steven R. Meikle

Achieving high image quality for temporal frames in dynamic positron emission tomography (PET) is challenging due to the limited statistic especially for the short frames. Recent studies have shown that deep learning (DL) is useful in a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Kuang Xiaodong , Li Bingxuan , Li Yuan , Rao Fan , Ma Gege , Xie Qingguo , Mok Greta S P , Liu Huafeng , Zhu Wentao

Nonnegative Matrix Factorization (NMF) has been continuously evolving in several areas like pattern recognition and information retrieval methods. It factorizes a matrix into a product of 2 low-rank non-negative matrices that will define…

Machine Learning · Computer Science 2013-04-04 Jing-Yan Wang , Mustafa AbdulJabbar

We perform a parametric study of the newly developed time-of-flight (TOF) image reconstruction algorithm, proposed for the real-time imaging in total-body Jagiellonian PET (J-PET) scanners. The asymmetric 3D filtering kernel is applied at…

Traditional nonnegative matrix factorization (NMF) learns a new feature representation on the whole data space, which means treating all features equally. However, a subspace is often sufficient for accurate representation in practical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Junhang Li , Jiao Wei , Can Tong , Tingting Shen , Yuchen Liu , Chen Li , Shouliang Qi , Yudong Yao , Yueyang Teng

We present a novel method for reconstructing a 3D implicit surface from a large-scale, sparse, and noisy point cloud. Our approach builds upon the recently introduced Neural Kernel Fields (NKF) representation. It enjoys similar…

Computer Vision and Pattern Recognition · Computer Science 2023-06-12 Jiahui Huang , Zan Gojcic , Matan Atzmon , Or Litany , Sanja Fidler , Francis Williams

In this paper we present a novel method for efficient and effective 3D surface reconstruction in open scenes. Existing Neural Radiance Fields (NeRF) based works typically require extensive training and rendering time due to the adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Gaochao Song , Chong Cheng , Hao Wang

Patient motion during PET is inevitable. Its long acquisition time not only increases the motion and the associated artifacts but also the patient's discomfort, thus PET acceleration is desirable. However, accelerating PET acquisition will…

Image and Video Processing · Electrical Eng. & Systems 2023-02-15 Bo Zhou , Yu-Jung Tsai , Jiazhen Zhang , Xueqi Guo , Huidong Xie , Xiongchao Chen , Tianshun Miao , Yihuan Lu , James S. Duncan , Chi Liu
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