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Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

A novel non-parametric estimator of the correlation between grouped measurements of a quantity is proposed in the presence of noise. This work is primarily motivated by functional brain network construction from fMRI data, where brain…

Methodology · Statistics 2023-02-16 Hanâ Lbath , Alexander Petersen , Wendy Meiring , Sophie Achard

Some of the most severe bottlenecks preventing widespread development of machine learning models for human behavior include a dearth of labeled training data and difficulty of acquiring high quality labels. Active learning is a paradigm for…

Objective. Modelling is an important way to study the working mechanism of brain. While the characterization and understanding of brain are still inadequate. This study tried to build a model of brain from the perspective of thermodynamics…

Neurons and Cognition · Quantitative Biology 2021-03-30 Chenxi Zhou , Bin Yang , Wenliang Fan , Wei Li

Neuroimaging datasets keep growing in size to address increasingly complex medical questions. However, even the largest datasets today alone are too small for training complex models or for finding genome wide associations. A solution is to…

Computer Vision and Pattern Recognition · Computer Science 2018-05-01 Christian Wachinger , Benjamin Gutierrez Becker , Anna Rieckmann

Autism Spectrum Disorder (ASD) is characterized by challenges with social interaction and communication and by restricted or repetitive patterns of thought and behavior, with significant variability in presentation. Approximately a quarter…

Artificial Intelligence · Computer Science 2026-05-21 Yadhu Kartha , Conor Anderson , Jenny Foster , Theresa Hamlin , Johanna Lantz , Ryan Lay , Juergen Hahn , Gari D. Clifford , Hyeokhyen Kwon

The cerebral cortex performs higher-order brain functions and is thus implicated in a range of cognitive disorders. Current analysis of cortical variation is typically performed by fitting surface mesh models to inner and outer cortical…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Samuel Budd , Prachi Patkee , Ana Baburamani , Mary Rutherford , Emma C. Robinson , Bernhard Kainz

An efficient algorithm for adaptive kernel smoothing (AKS) of two-dimensional imaging data has been developed and implemented using the Interactive Data Language (IDL). The functional form of the kernel can be varied (top-hat, Gaussian…

Astrophysics · Physics 2009-11-11 H. Ebeling , D. A. White , F. V. N. Rangarajan

Autism spectrum disorder (ASD) affects the brain connectivity at different levels. Nonetheless, non-invasively distinguishing such effects using magnetic resonance imaging (MRI) remains very challenging to machine learning diagnostic…

Machine Learning · Computer Science 2020-04-29 Ismail Bilgen , Goktug Guvercin , Islem Rekik

Mental disorders such as Autism Spectrum Disorders (ASD) are heterogeneous disorders that are notoriously difficult to diagnose, especially in children. The current psychiatric diagnostic process is based purely on the behavioural…

Machine Learning · Computer Science 2019-04-17 Taban Eslami , Vahid Mirjalili , Alvis Fong , Angela Laird , Fahad Saeed

Brain connectivity with functional Magnetic Resonance Imaging (fMRI) is a popular approach for detecting differences between healthy and clinical populations. Before creating a functional brain network, the fMRI time series must undergo…

Neurons and Cognition · Quantitative Biology 2020-02-20 A. M. Triana , E. Glerean , J. Saramäki , O. Korhonen

Mantel's test (MT) for association is conducted by testing the linear relationship of similarity of all pairs of subjects between two observational domains. Motivated by applications to neuroimaging and genetics data, and following the…

Methodology · Statistics 2018-12-18 Dustin Pluta , Hernando Ombao , Chuansheng Chen , Gui Xue , Robert Moyzis , Zhaoxia Yu

Functional Magnetic Resonance Imaging (fMRI) captures the temporal dynamics of neural activity as a function of spatial location in the brain. Thus, fMRI scans are represented as 4-Dimensional (3-space + 1-time) tensors. And it is widely…

Computer Vision and Pattern Recognition · Computer Science 2020-02-17 Ahmed El-Gazzar , Mirjam Quaak , Leonardo Cerliani , Peter Bloem , Guido van Wingen , Rajat Mani Thomas

To understand Working of Human Brain measurements related to the brain function are required. These measurements should be possibly non-invasive. Brain should be disturbed as less as possible during the measurement. Integration of various…

Emerging Technologies · Computer Science 2015-06-16 Revati Shriram , M. Sundhararajan , Nivedita Daimiwal

Using the action sequence data (i.e., log data) from the problem-solving in technology-rich environments assessment on the 2012 Programme for the International Assessment of Adult Competencies survey, the current study examines the…

Applications · Statistics 2021-03-30 Susu Zhang , Xueying Tang , Qiwei He , Jingchen Liu , Zhiliang Ying

In the literature of cognitive neuroscience, researchers tend to assume a linear relationship between brain activation level and task performance; however, controversial findings have been reported in participants at different ages and…

Neurons and Cognition · Quantitative Biology 2025-10-17 Fan Cao , Yuqi Yuan , Xiaohui Yan , Bohan Zhang , Kyle Perkins

Autism Spectrum Condition (ASC) is a neurodevelopmental condition characterized by impairments in communication, social interaction and restricted or repetitive behaviors. Extensive research has been conducted to identify distinctions…

Quantitative Methods · Quantitative Biology 2024-05-22 F. J. Alcaide , I. A. Illan , J. Ramirez , J. M. Gorriz

Resting-state fMRI is commonly used for diagnosing Autism Spectrum Disorder (ASD) by using network-based functional connectivity. It has been shown that ASD is associated with brain regions and their inter-connections. However,…

Neurons and Cognition · Quantitative Biology 2022-01-04 Ranjeet Ranjan Jha , Abhishek Bhardwaj , Devin Garg , Arnav Bhavsar , Aditya Nigam

The correlation matrix is a central representation of functional brain networks in neuroimaging. Traditional analyses often treat pairwise interactions independently in a Euclidean setting, overlooking the intrinsic geometry of correlation…

Machine Learning · Statistics 2025-04-10 Kisung You , Yelim Lee , Hae-Jeong Park

The vast majority of fMRI studies of task-related brain activity utilize common levels of task demands and analyses that rely on the central tendencies of the data. This approach does not take into account perceived difficulty nor regional…

Neurons and Cognition · Quantitative Biology 2021-10-14 Jason Steffener , Chris Habeck , Dylan Franklin , Meghan Lau , Yara Yakoub , Maryse Gad