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Controlling polymorphism in molecular crystals is crucial in the pharmaceutical, dye, and pesticide industries. However, its theoretical description is extremely challenging, due to the associated long timescales ($ > 1 \, \mu s$). We…

Chemical Physics · Physics 2023-02-09 Oren Elishav , Roy Podgaetsky , Olga Meikler , Barak Hirshberg

The committor function is a central object for quantifying the transitions between metastable states of dynamical systems. Recently, a number of computational methods based on deep neural networks have been developed for computing the…

Computational Physics · Physics 2024-04-10 Bo Lin , Weiqing Ren

Transformer language models (LMs) exhibit behaviors -- from storytelling to code generation -- that seem to require tracking the unobserved state of an evolving world. How do they do this? We study state tracking in LMs trained or…

Computation and Language · Computer Science 2025-11-03 Belinda Z. Li , Zifan Carl Guo , Jacob Andreas

For recurrent neural networks trained on time series with target and exogenous variables, in addition to accurate prediction, it is also desired to provide interpretable insights into the data. In this paper, we explore the structure of…

Machine Learning · Computer Science 2019-05-30 Tian Guo , Tao Lin , Nino Antulov-Fantulin

Learning meaningful abstract models of Markov Decision Processes (MDPs) is crucial for improving generalization from limited data. In this work, we show how geometric priors can be imposed on the low-dimensional representation manifold of a…

Machine Learning · Computer Science 2026-05-20 Thomas Delliaux , Nguyen-Khanh Vu , Vincent François-Lavet , Elise van der Pol , Emmanuel Rachelson

We propose an iterative proposal to estimate critical points for statistical models based on configurations by combing machine-learning tools. Firstly, phase scenarios and preliminary boundaries of phases are obtained by…

Disordered Systems and Neural Networks · Physics 2019-10-23 X. L. Zhao , L. B. Fu

Learning disentangled representations is a key step towards effectively discovering and modelling the underlying structure of environments. In the natural sciences, physics has found great success by describing the universe in terms of…

Machine Learning · Computer Science 2020-10-27 Robin Quessard , Thomas D. Barrett , William R. Clements

Recurrent neural networks for language models like long short-term memory (LSTM) have been utilized as a tool for modeling and predicting long term dynamics of complex stochastic molecular systems. Recently successful examples on learning…

Artificial Intelligence · Computer Science 2021-07-15 Wenqi Zeng , Siqin Cao , Xuhui Huang , Yuan Yao

The introduction of convolutional layers greatly advanced the performance of neural networks on image tasks due to innately capturing a way of encoding and learning translation-invariant operations, matching one of the underlying symmetries…

Computer Vision and Pattern Recognition · Computer Science 2016-12-15 Nicholas Guttenberg , Nathaniel Virgo , Olaf Witkowski , Hidetoshi Aoki , Ryota Kanai

Modeling symmetry breaking is essential for understanding the fundamental changes in the behaviors and properties of physical systems, from microscopic particle interactions to macroscopic phenomena like fluid dynamics and cosmic…

Machine Learning · Computer Science 2025-07-11 Rui Wang , Elyssa Hofgard , Han Gao , Robin Walters , Tess E. Smidt

The main goal of this paper is to understand the formation of hexagonal patterns from the dynamical transition theory point of view. We consider the transitions from a steady state of an abstract nonlinear dissipative system. To shed light…

Mathematical Physics · Physics 2020-08-26 Taylan Şengül

Decomposing knowledge into interchangeable pieces promises a generalization advantage when there are changes in distribution. A learning agent interacting with its environment is likely to be faced with situations requiring novel…

Machine Learning · Computer Science 2021-05-20 Kanika Madan , Nan Rosemary Ke , Anirudh Goyal , Bernhard Schölkopf , Yoshua Bengio

Fitting generative models to sequential data typically involves two recursive computations through time, one forward and one backward. The latter could be a computation of the loss gradient (as in backpropagation through time), or an…

Machine Learning · Computer Science 2023-10-23 Azwar Abdulsalam , Joseph G. Makin

In this paper we combine two powerful computational techniques, well-tempered metadynamics and time lagged independent component analysis. The aim is to develop a new tool for studying rare events and exploring complex free energy…

Statistical Mechanics · Physics 2017-12-08 James McCarty , Michele Parrinello

The recent success of Transformers in the language domain has motivated adapting it to a multimodal setting, where a new visual model is trained in tandem with an already pretrained language model. However, due to the excessive memory…

Computer Vision and Pattern Recognition · Computer Science 2021-09-23 Sangho Lee , Youngjae Yu , Gunhee Kim , Thomas Breuel , Jan Kautz , Yale Song

We employ variational autoencoders to extract physical insight from a dataset of one-particle Anderson impurity model spectral functions. Autoencoders are trained to find a low-dimensional, latent space representation that faithfully…

Strongly Correlated Electrons · Physics 2021-12-22 Cole Miles , Matthew R. Carbone , Erica J. Sturm , Deyu Lu , Andreas Weichselbaum , Kipton Barros , Robert M. Konik

We investigate sample-based learning of conditional distributions on multi-dimensional unit boxes, allowing for different dimensions of the feature and target spaces. Our approach involves clustering data near varying query points in the…

Machine Learning · Statistics 2024-06-14 Cyril Bénézet , Ziteng Cheng , Sebastian Jaimungal

The computational study of conformational transitions in RNA and proteins with atomistic molecular dynamics often requires suitable enhanced sampling techniques. We here introduce a novel method where concurrent metadynamics are integrated…

Computational Physics · Physics 2015-09-01 Alejandro Gil-Ley , Giovanni Bussi

Transformers have proven highly effective across various applications, especially in handling sequential data such as natural languages and time series. However, transformer models often lack clear interpretability, and the success of…

Machine Learning · Computer Science 2025-12-01 Wei Shi , Yuan Cao

Clinical machine learning applications are often plagued with confounders that are clinically irrelevant, but can still artificially boost the predictive performance of the algorithms. Confounding is especially problematic in mobile health…

Applications · Statistics 2018-11-29 Elias Chaibub Neto