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Living systems continuously transform matter and energy through the chemical processes that constitute their metabolism. The overall metabolic rate of an organism correlates positively with its body mass, however both the exact scaling…

Soft Condensed Matter · Physics 2026-03-19 Efe Ilker , Michael Hinczewski , Xingbo Yang , Frank Jülicher

Predicting structural and energetic properties of a molecular system is one of the fundamental tasks in molecular simulations, and it has use cases in chemistry, biology, and medicine. In the past decade, the advent of machine learning…

Chemical Physics · Physics 2022-08-23 Sajjad Heydari , Stefano Raniolo , Lorenzo Livi , Vittorio Limongelli

Multi-lingual language models (LM), such as mBERT, XLM-R, mT5, mBART, have been remarkably successful in enabling natural language tasks in low-resource languages through cross-lingual transfer from high-resource ones. In this work, we try…

Computation and Language · Computer Science 2022-12-06 Benjamin Muller , Deepanshu Gupta , Siddharth Patwardhan , Jean-Philippe Fauconnier , David Vandyke , Sachin Agarwal

Link prediction aims to identify potential missing triples in knowledge graphs. To get better results, some recent studies have introduced multimodal information to link prediction. However, these methods utilize multimodal information…

Artificial Intelligence · Computer Science 2023-03-21 Xinhang Li , Xiangyu Zhao , Jiaxing Xu , Yong Zhang , Chunxiao Xing

Metabolic heterogeneity is widely recognised as the next challenge in our understanding of non-genetic variation. A growing body of evidence suggests that metabolic heterogeneity may result from the inherent stochasticity of intracellular…

Molecular Networks · Quantitative Biology 2020-10-08 Mona K Tonn , Philipp Thomas , Mauricio Barahona , Diego A Oyarzún

Most existing methods focus on sentiment analysis of textual data. However, recently there has been a massive use of images and videos on social platforms, motivating sentiment analysis from other modalities. Current studies show that…

Machine Learning · Computer Science 2022-10-13 Guilherme Lourenço de Toledo , Ricardo Marcondes Marcacini

Efficient and scalable non-parametric or semi-parametric regression analysis and density estimation are of crucial importance to the fields of statistics and machine learning. However, available methods are limited in their ability to…

Machine Learning · Computer Science 2026-03-23 Zeyu Ding , Katja Ickstadt , Nadja Klein , Alexander Munteanu , Simon Omlor

This paper presents a machine learning approach to multidimensional item response theory (MIRT), a class of latent factor models that can be used to model and predict student performance from observed assessment data. Inspired by…

Machine Learning · Statistics 2025-01-08 Yoav Bergner , Peter F. Halpin , Jill-Jênn Vie

Metabolomic data sets provide a direct read-out of cellular phenotypes and are increasingly generated to study biological questions. Our previous work revealed the potential of analyzing extracellular metabolomic data in the context of the…

Molecular Networks · Quantitative Biology 2016-06-10 Maike K. Aurich , Ronan M. T. Fleming , Ines Thiele

Synthesizing amyloid PET scans from the more widely available and accessible structural MRI modality offers a promising, cost-effective approach for large-scale Alzheimer's Disease (AD) screening. This is motivated by evidence that, while…

Image and Video Processing · Electrical Eng. & Systems 2025-11-12 Alec Sargood , Lemuel Puglisi , James H. Cole , Neil P. Oxtoby , Daniele Ravì , Daniel C. Alexander

Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…

Leveraging the vast genetic diversity within microbiomes offers unparalleled insights into complex phenotypes, yet the task of accurately predicting and understanding such traits from genomic data remains challenging. We propose a framework…

Genomics · Quantitative Biology 2025-03-05 Zhufeng Li , Sandeep S Cranganore , Nicholas Youngblut , Niki Kilbertus

Nowadays, new branches of research are proposing the use of non-traditional data sources for the study of migration trends in order to find an original methodology to answer open questions about the human mobility framework. In this context…

Social and Information Networks · Computer Science 2022-05-04 D. Goglia , L. Pollacci , A. Sirbu

Modern multilingual models are trained on concatenated text from multiple languages in hopes of conferring benefits to each (positive transfer), with the most pronounced benefits accruing to low-resource languages. However, recent work has…

Computation and Language · Computer Science 2020-10-08 Zirui Wang , Zachary C. Lipton , Yulia Tsvetkov

Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…

Populations and Evolution · Quantitative Biology 2022-01-19 Jacob Cook , Samraat Pawar , Robert G. Endres

This paper focuses on data arising from the field of metabolomics, a rapidly developing area concerned by the analysis of the chemical fingerprints (i.e. the metabolite profile). The metabolite profile is left by specific chemical processes…

Applications · Statistics 2014-02-06 Charanpal Dhanjal , Stéphan Clémençon

Isotopically non-stationary metabolic flux analysis (INST $^{13}$C-MFA) provides unique insights into cellular physiology but is typically limited by low throughput and high experimental costs. Here, we present a miniaturized and automated…

Quantitative Methods · Quantitative Biology 2026-05-26 Jochen Nießer , Anton Stratmann , Martin Beyß , Wolfgang Wiechert , Katharina Nöh , Stephan Noack

Metabolomic data can potentially enable accurate, non-invasive and low-cost prediction of coronary artery disease. Regression-based analytical approaches however might fail to fully account for interactions between metabolites, rely on a…

Transferability estimation has emerged as an important problem in transfer learning. A transferability estimation method takes as inputs a set of pre-trained models and decides which pre-trained model can deliver the best transfer learning…

Machine Learning · Computer Science 2024-05-06 Yunhui Guo

Decentralized collaborative learning under data heterogeneity and privacy constraints has rapidly advanced. However, existing solutions like federated learning, ensembles, and transfer learning, often fail to adequately serve the unique…

Machine Learning · Computer Science 2025-04-15 Norah Alballa , Wenxuan Zhang , Ziquan Liu , Ahmed M. Abdelmoniem , Mohamed Elhoseiny , Marco Canini