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Current imaging methods for diagnosing BC are associated with limited sensitivity and specificity and modest positive predictive power. The recent progress in image analysis using artificial intelligence (AI) has created great promise to…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Reza Elahi , Mahdis Nazari

Spatial omics (SO) technologies enable spatially resolved molecular profiling, while hematoxylin and eosin (H&E) imaging remains the gold standard for morphological assessment in clinical pathology. Recent computational advances…

Multiplex immunofluorescence (mIF) imaging technology facilitates the study of the tumour microenvironment in cancer patients. Due to the capabilities of this emerging bioimaging technique, it is possible to statistically analyse, for…

Applications · Statistics 2023-07-07 Jonatan A. González , Julia Wrobel , Simon Vandekar , Paula Moraga

Artificial intelligence (AI) techniques for image-based segmentation have garnered much attention in recent years. Convolutional neural networks (CNNs) have shown impressive results and potential towards fully automated segmentation in…

Medical Physics · Physics 2021-11-17 Fereshteh Yousefirizi , Abhinav K. Jha , Julia Brosch-Lenz , Babak Saboury , Arman Rahmim

Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To develop such a predictive model, one must…

Cell Behavior · Quantitative Biology 2015-05-20 Salvatore Torquato

Cancer remains one of the most challenging diseases to treat in the medical field. Machine learning has enabled in-depth analysis of rich multi-omics profiles and medical imaging for cancer diagnosis and prognosis. Despite these…

Machine Learning · Computer Science 2024-01-15 Lingchao Mao , Hairong Wang , Leland S. Hu , Nhan L Tran , Peter D Canoll , Kristin R Swanson , Jing Li

Recent breakthroughs in artificial intelligence through foundation models and agents have accelerated the evolution of computational pathology. Demonstrated performance gains reported across academia in benchmarking datasets in predictive…

Spatial computing is a technological advancement that facilitates the seamless integration of devices into the physical environment, resulting in a more natural and intuitive digital world user experience. Spatial computing has the…

Digital pathology is not only one of the most promising fields of diagnostic medicine, but at the same time a hot topic for fundamental research. Digital pathology is not just the transfer of histopathological slides into digital…

Artificial Intelligence · Computer Science 2017-12-20 Andreas Holzinger , Bernd Malle , Peter Kieseberg , Peter M. Roth , Heimo Müller , Robert Reihs , Kurt Zatloukal

Recent advancements in model checking have demonstrated significant potential across diverse applications, particularly in signal and image analysis. Medical imaging stands out as a critical domain where model checking can be effectively…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Elhoucine Elfatimi , Lahcen El fatimi

Melanoma represents a critical health risk due to its aggressive progression and high mortality, underscoring the need for early, interpretable diagnostic tools. While deep learning has advanced in skin lesion classification, most existing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Ciro Listone , Aniello Murano

Lung cancer remains one of the most prevalent and fatal diseases worldwide, demanding accurate and timely diagnosis and treatment. Recent advancements in large AI models have significantly enhanced medical image understanding and clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Jiachen Zhong , Yiting Wang , Di Zhu , Ziwei Wang

Computational pathology is part of precision oncology medicine. The integration of high-throughput data including genomics, transcriptomics, proteomics, metabolomics, pathomics, and radiomics into clinical practice improves cancer treatment…

Image and Video Processing · Electrical Eng. & Systems 2022-06-07 Liangrui Pan , Zhichao Feng , Shaoliang Peng

Algorithmic strategies for the spatio-temporal simulation of multi-cellular systems are crucial to generate synthetic datasets for bioinformatics tools benchmarking, as well as to investigate experimental hypotheses on real-world systems in…

Populations and Evolution · Quantitative Biology 2021-10-14 Fabrizio Angaroni , Marco Antoniotti , Alex Graudenzi

Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics…

Quantitative Methods · Quantitative Biology 2020-06-30 Andreas Mang , Spyridon Bakas , Shashank Subramanian , Christos Davatzikos , George Biros

With advanced imaging, sequencing, and profiling technologies, multiple omics data become increasingly available and hold promises for many healthcare applications such as cancer diagnosis and treatment. Multimodal learning for integrative…

Genomics · Quantitative Biology 2022-12-20 Sina Tabakhi , Mohammod Naimul Islam Suvon , Pegah Ahadian , Haiping Lu

The rising incidence of skin cancer, coupled with limited public awareness and a shortfall in clinical expertise, underscores an urgent need for advanced diagnostic aids. Artificial Intelligence (AI) has emerged as a promising tool in this…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Hamideh Khaleghpour , Brett McKinney

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

A primary goal of modern cancer research is to characterize tumour growth and evolution, to improve clinical forecasting and individualized treatment. Agent-based models support this endeavour but existing models either oversimplify spatial…

Quantitative Methods · Quantitative Biology 2023-01-20 Maciej Bak , Blair Colyer , Veselin Manojlović , Robert Noble

Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou