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We consider estimating a low-dimensional parameter in an estimating equation involving high-dimensional nuisances that depend on the parameter. A central example is the efficient estimating equation for the (local) quantile treatment effect…

Machine Learning · Statistics 2022-08-18 Nathan Kallus , Xiaojie Mao , Masatoshi Uehara

For a data-generating process for random variables that can be described with a linear structural equation model, we consider a situation in which (i) a set of covariates satisfying the back-door criterion cannot be observed or (ii) such a…

Methodology · Statistics 2025-03-06 Hisayoshi Nanmo , Manabu Kuroki

Mixed linear regression (MLR) has attracted increasing attention because of its great theoretical and practical importance in capturing nonlinear relationships by utilizing a mixture of linear regression sub-models. Although considerable…

Machine Learning · Statistics 2025-03-25 Yujing Liu , Zhixin Liu , Lei Guo

We consider the estimation of treatment effects in settings when multiple treatments are assigned over time and treatments can have a causal effect on future outcomes or the state of the treated unit. We propose an extension of the…

Econometrics · Economics 2021-06-18 Greg Lewis , Vasilis Syrgkanis

With the excellent representation capabilities of Pre-Trained Models (PTMs), remarkable progress has been made in non-rehearsal Class-Incremental Learning (CIL) research. However, it remains an extremely challenging task due to three…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Jiawei Zhan , Jun Liu , Jinlong Peng , Xiaochen Chen , Bin-Bin Gao , Yong Liu , Chengjie Wang

Nonlinear machine-learning models are increasingly used to discover causal relationships in time-series data, yet the interpretation of their outputs remains poorly understood. In particular, causal scores produced by regularized neural…

Machine Learning · Computer Science 2026-05-27 Valentina Kuskova , Dmitry Zaytsev , Michael Coppedge

Causal machine learning (ML) offers flexible, data-driven methods for predicting treatment outcomes including efficacy and toxicity, thereby supporting the assessment and safety of drugs. A key benefit of causal ML is that it allows for…

Context-based offline meta-reinforcement learning (OMRL) methods have achieved appealing success by leveraging pre-collected offline datasets to develop task representations that guide policy learning. However, current context-based OMRL…

Machine Learning · Computer Science 2025-02-04 Zhengzhe Zhang , Wenjia Meng , Haoliang Sun , Gang Pan

Mixed Models for Repeated Measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are…

Methodology · Statistics 2023-01-23 Lars Lau Raket

Empirical researchers increasingly use upstream machine-learning (ML) methods to construct proxies for latent target variables from complex, unstructured data. A naive plug-in use of such proxies in downstream econometric models, however,…

Econometrics · Economics 2026-04-14 Lixiong Li

A new dimensional reduction (DR) and data visualization method, Curvature-Augmented Manifold Embedding and Learning (CAMEL), is proposed. The key novel contribution is to formulate the DR problem as a mechanistic/physics model, where the…

Machine Learning · Statistics 2024-03-25 Yongming Liu

A number of methods have been proposed for causal effect estimation, yet few have demonstrated efficacy in handling data with complex structures, such as images. To fill this gap, we propose Causal Multi-task Deep Ensemble (CMDE), a novel…

Machine Learning · Computer Science 2023-05-30 Ziyang Jiang , Zhuoran Hou , Yiling Liu , Yiman Ren , Keyu Li , David Carlson

Machine learning is a vital part of many real-world systems, but several concerns remain about the lack of interpretability, explainability and robustness of black-box AI systems. Concept Bottleneck Models (CBM) address some of these…

Machine Learning · Statistics 2025-10-24 Hidde Fokkema , Tim van Erven , Sara Magliacane

In this study, a scalable online kernel learning framework is proposed for estimating bidirectional causal effects in systems characterized by mutual dependence and heteroskedasticity. Traditional causal inference often focuses on…

Machine Learning · Statistics 2025-11-24 Masahiro Tanaka

Panel data methods are widely used in empirical analysis to address unobserved heterogeneity, but causal inference remains challenging when treatments are endogenous and confounding variables high-dimensional and potentially nonlinear.…

Econometrics · Economics 2026-03-24 Anna Baiardi , Paul S. Clarke , Andrea A. Naghi , Annalivia Polselli

Recently, molecular relational learning, whose goal is to predict the interaction behavior between molecular pairs, got a surge of interest in molecular sciences due to its wide range of applications. In this work, we propose CMRL that is…

Machine Learning · Computer Science 2023-07-24 Namkyeong Lee , Kanghoon Yoon , Gyoung S. Na , Sein Kim , Chanyoung Park

In health and social sciences, it is critically important to identify subgroups of the study population where there is notable heterogeneity of treatment effects (HTE) with respect to the population average. Decision trees have been…

Methodology · Statistics 2024-05-28 Falco J. Bargagli-Stoffi , Riccardo Cadei , Kwonsang Lee , Francesca Dominici

Uncovering cause-effect relationships from observational time series is fundamental to understanding complex systems. While many methods infer static causal graphs, real-world systems often exhibit dynamic causality-where relationships…

Machine Learning · Computer Science 2025-11-06 Tingzhu Bi , Yicheng Pan , Xinrui Jiang , Huize Sun , Meng Ma , Ping Wang

Establishing causality is a fundamental goal in fields like medicine and social sciences. While randomized controlled trials are the gold standard for causal inference, they are not always feasible or ethical. Observational studies can…

Statistics Theory · Mathematics 2024-12-03 Andrew Ying

This paper presents a methodological approach to financial time series analysis by combining causal discovery and uncertainty-aware forecasting. As a case study, we focus on four key U.S. macroeconomic indicators -- GDP, economic growth,…

Machine Learning · Computer Science 2025-10-27 Federico Cerutti
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