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Manifold learning techniques play a pivotal role in machine learning by revealing lower-dimensional embeddings within high-dimensional data, thus enhancing both the efficiency and interpretability of data analysis by transforming the data…

Neural and Evolutionary Computing · Computer Science 2025-05-02 Ben Cravens , Andrew Lensen , Paula Maddigan , Bing Xue

The gamma belief network (GBN), often regarded as a deep topic model, has demonstrated its potential for uncovering multi-layer interpretable latent representations in text data. Its notable capability to acquire interpretable latent…

Machine Learning · Computer Science 2024-08-16 Zhibin Duan , Tiansheng Wen , Muyao Wang , Bo Chen , Mingyuan Zhou

Recent research has demonstrated that feature attribution methods for deep networks can themselves be incorporated into training; these attribution priors optimize for a model whose attributions have certain desirable properties -- most…

Machine Learning · Computer Science 2020-11-12 Gabriel Erion , Joseph D. Janizek , Pascal Sturmfels , Scott Lundberg , Su-In Lee

Integrating large language models (LLMs) with knowledge graphs derived from domain-specific data represents an important advancement towards more powerful and factual reasoning. As these models grow more capable, it is crucial to enable…

Artificial Intelligence · Computer Science 2024-04-19 Stefan Dernbach , Khushbu Agarwal , Alejandro Zuniga , Michael Henry , Sutanay Choudhury

Inferring Gene Regulatory Networks (GRNs) from gene expression data is crucial for understanding biological processes. While supervised models are reported to achieve high performance for this task, they rely on costly ground truth (GT)…

Machine Learning · Statistics 2025-06-10 Tianyu Cui , Song-Jun Xu , Artem Moskalev , Shuwei Li , Tommaso Mansi , Mangal Prakash , Rui Liao

The graph classification problem has been widely studied; however, achieving an interpretable model with high predictive performance remains a challenging issue. This paper proposes an interpretable classification algorithm for attributed…

Machine Learning · Computer Science 2024-02-13 Tajima Shinji , Ren Sugihara , Ryota Kitahara , Masayuki Karasuyama

The generative nature of Large Language Models (LLMs) is reflected in the conditional probabilities they compute to sample each response token given the previous tokens. These probabilities encode the distributional structure that the model…

Computation and Language · Computer Science 2026-05-22 Shilpika Shilpika , Carlo Graziani , Bethany Lusch , Venkatram Vishwanath , Michael E. Papka

Data valuation plays a crucial role in machine learning. Existing data valuation methods, mainly focused on discriminative models, overlook generative models that have gained attention recently. In generative models, data valuation measures…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Jiaxi Yang , Wenglong Deng , Benlin Liu , Yangsibo Huang , James Zou , Xiaoxiao Li

Gene expression is a cellular process that plays a fundamental role in human phenotypical variations and diseases. Despite advances of deep learning models for gene expression prediction, recent benchmarks have revealed their inability to…

Cell Behavior · Quantitative Biology 2024-10-04 Edouardo Honig , Huixin Zhan , Ying Nian Wu , Zijun Frank Zhang

We introduce AiM, an autoregressive (AR) image generative model based on Mamba architecture. AiM employs Mamba, a novel state-space model characterized by its exceptional performance for long-sequence modeling with linear time complexity,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Haopeng Li , Jinyue Yang , Kexin Wang , Xuerui Qiu , Yuhong Chou , Xin Li , Guoqi Li

Large language models (LLMs) have shown remarkable capabilities in various natural language tasks and are increasingly being applied in healthcare domains. This work demonstrates a new LLM-powered disease risk assessment approach via…

Computation and Language · Computer Science 2024-09-24 Mohammad Amin Roshani , Xiangyu Zhou , Yao Qiang , Srinivasan Suresh , Steve Hicks , Usha Sethuraman , Dongxiao Zhu

Recent strides in interpretable machine learning (ML) research reveal that models exploit undesirable patterns in the data to make predictions, which potentially causes harms in deployment. However, it is unclear how we can fix these…

Interpretability remains a key challenge for deploying large language models (LLMs) in clinical settings such as Alzheimer's disease progression diagnosis, where early and trustworthy predictions are essential. Existing attribution methods…

Medical imaging is an essential tool for diagnosing and treating diseases. However, lacking medical images can lead to inaccurate diagnoses and ineffective treatments. Generative models offer a promising solution for addressing medical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-02 M. AbdulRazek , G. Khoriba , M. Belal

Attention is a general reasoning mechanism than can flexibly deal with image information, but its memory requirements had made it so far impractical for high resolution image generation. We present Grid Partitioned Attention (GPA), a new…

Computer Vision and Pattern Recognition · Computer Science 2021-07-09 Nikolay Jetchev , Gökhan Yildirim , Christian Bracher , Roland Vollgraf

Anomaly detection (AD) has attracted considerable attention in both academia and industry. Due to the lack of anomalous data in many practical cases, AD is usually solved by first modeling the normal data pattern and then determining if…

Machine Learning · Computer Science 2022-11-17 Jingxuan Pang , Chunguang Li

Interpreting the decisions of complex computer vision models is crucial to establish trust and accountability, especially in safety-critical domains. An established approach to interpretability is generating visual attribution maps that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 David Schinagl , Christian Fruhwirth-Reisinger , Alexander Prutsch , Samuel Schulter , Horst Possegger

Fine-tuning large language models (LLMs) for alignment typically relies on supervised fine-tuning or reinforcement learning from human feedback, both limited by the cost and scarcity of high-quality annotations. Recent self-play and…

Machine Learning · Computer Science 2026-02-03 Shiguang Wu , Yaqing Wang , Quanming Yao

Training large language models (LLMs) typically involves pre-training on massive corpora, only to restart the process entirely when new data becomes available. A more efficient and resource-conserving approach would be continual…

Identifying anomalies refers to detecting samples that do not resemble the training data distribution. Many generative models have been used to find anomalies, and among them, generative adversarial network (GAN)-based approaches are…

Machine Learning · Computer Science 2022-01-03 Laya Rafiee Sevyeri , Thomas Fevens