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Complex spatiotemporal patterns, called chimera states, consist of coexisting coherent and incoherent domains and can be observed in networks of coupled oscillators. The interplay of synchrony and asynchrony in complex brain networks is an…

Adaptation and Self-Organizing Systems · Physics 2019-06-20 Teresa Chouzouris , Iryna Omelchenko , Anna Zakharova , Jaroslav Hlinka , Premysl Jiruska , Eckehard Schöll

With our ability to record more neurons simultaneously, making sense of these data is a challenge. Functional connectivity is one popular way to study the relationship between multiple neural signals. Correlation-based methods are a set of…

Neurons and Cognition · Quantitative Biology 2017-06-09 Tiger W. Lin , Anup Das , Giri P. Krishnan , Maxim Bazhenov , Terrence J. Sejnowski

The effects of nonlocal and reflecting connectivities have been previously investigated in coupled Leaky Integrate-and-Fire (LIF) elements, which assimilate the exchange of electrical signals between neurons. In this work we investigate the…

Pattern Formation and Solitons · Physics 2018-10-16 N. D. Tsigkri-DeSmedt , I. Koulierakis , G. Karakos , A. Provata

Recent advances in experimental neuroscience allow, for the first time, non-invasive studies of the white matter tracts in the human central nervous system, thus making available cutting-edge brain anatomical data describing these global…

Quantitative Methods · Quantitative Biology 2008-11-06 Jonathan J. Crofts , Desmond J. Higham

Rapid experimental advances now enable simultaneous electrophysiological recording of neural activity at single-cell resolution across large regions of the nervous system. Models of this neural network activity will necessarily increase in…

Neurons and Cognition · Quantitative Biology 2017-10-02 Andrea K. Barreiro , Cheng Ly

Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…

Applications · Statistics 2023-01-24 Nathan Tung , Jerome Sanes , Eli Upfal , Ani Eloyan

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Analysis of brain connectivity is important for understanding how information is processed by the brain. We propose a novel Bayesian vector autoregression (VAR) hierarchical model for analyzing brain connectivity in a resting-state fMRI…

Applications · Statistics 2021-12-09 Bertil Wegmann , Anders Lundquist , Anders Eklund , Mattias Villani

Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

Neurons and Cognition · Quantitative Biology 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

Functional connectivity refers to the temporal statistical relationship between spatially distinct brain regions and is usually inferred from the time series coherence/correlation in brain activity between regions of interest. In human…

Machine Learning · Statistics 2015-03-02 Shaurabh Nandy , Richard M. Golden

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…

Neurons and Cognition · Quantitative Biology 2020-01-20 Nicola Pedreschi , Christophe Bernard , Wesley Clawson , Pascale Quilichini , Alain Barrat , Demian Battaglia

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

This paper describes an approach of using dynamic Structural Equation Modeling (SEM) analysis to estimate the connectivity networks from resting-state fMRI data measured by a multiband EPI sequence. Two structural equation models were…

Neurons and Cognition · Quantitative Biology 2017-04-03 Jiancheng Zhuang

Functional connectivity is a key approach to investigate oscillatory activities of the brain that provides important insights on the underlying dynamic of neuronal interactions and that is mostly applied for brain activity analysis.…

Neurons and Cognition · Quantitative Biology 2022-02-17 Marie-Constance Corsi , Sylvain Chevallier , Fabrizio De Vico Fallani , Florian Yger

Synaptic plasticity and neuron cross-talk are some of the important key mechanisms underlying formation of dynamic clusters of active neurons. The essence of this study is to model and decipher the mechanism of emergence of a task-specific…

Neurons and Cognition · Quantitative Biology 2021-08-03 Jasleen Gund , R. K. Brojen Singh

Computational models of cortical activity provide insight into the mechanisms of higher-order processing in the human brain including planning, perception and the control of movement. Activity in the cortex is ongoing even in the absence of…

Neurons and Cognition · Quantitative Biology 2023-07-07 Lysea Haggie , Thor Besier , Angus McMorland

A reliable foundation model of functional neuroimages is critical to promote clinical applications where the performance of current AI models is significantly impeded by a limited sample size. To that end, tremendous efforts have been made…

Machine Learning · Computer Science 2025-10-23 Ziquan Wei , Tingting Dan , Guorong Wu

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

The study of functional brain connectivity (FC) is important for understanding the underlying mechanisms of many psychiatric disorders. Many recent analyses adopt graph convolutional networks, to study non-linear interactions between…

Neurons and Cognition · Quantitative Biology 2021-09-08 Simon Dahan , Logan Z. J. Williams , Daniel Rueckert , Emma C. Robinson