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In the landscape of generative artificial intelligence, diffusion-based models have emerged as a promising method for generating synthetic images. However, the application of diffusion models poses numerous challenges, particularly…

Machine Learning · Computer Science 2026-05-04 Simeon Allmendinger , Domenique Zipperling , Lukas Struppek , Niklas Kühl

Predicting drug-target affinity is fundamental to virtual screening and lead optimization. However, existing deep models often suffer from representation collapse in stringent cold-start regimes, where the scarcity of labels and domain…

Machine Learning · Statistics 2026-03-13 Yining Qian , Pengjie Wang , Yixiao Li , An-Yang Lu , Cheng Tan , Shuang Li , Lijun Liu

Skin lesion segmentation plays a critical role in the early detection and accurate diagnosis of dermatological conditions. Denoising Diffusion Probabilistic Models (DDPMs) have recently gained attention for their exceptional…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Afshin Bozorgpour , Yousef Sadegheih , Amirhossein Kazerouni , Reza Azad , Dorit Merhof

Medical image segmentation is crucial for computer-aided diagnosis, which necessitates understanding both coarse morphological and semantic structures, as well as carving fine boundaries. The morphological and semantic structures in medical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Siyuan Song , Guyue Hu , Chenglong Li , Dengdi Sun , Zhe Jin , Jin Tang

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

In this study, the performance of existing U-shaped neural network architectures was enhanced for medical image segmentation by adding Transformer. Although Transformer architectures are powerful at extracting global information, its…

Image and Video Processing · Electrical Eng. & Systems 2024-04-12 Songkai Sun , Qingshan She , Yuliang Ma , Rihui Li , Yingchun Zhang

Large annotated datasets are required for training deep learning models, but in medical imaging data sharing is often complicated due to ethics, anonymization and data protection legislation. Generative AI models, such as generative…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Muhammad Usman Akbar , Måns Larsson , Anders Eklund

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Image stitching from different captures often results in non-rectangular boundaries, which is often considered unappealing. To solve non-rectangular boundaries, current solutions involve cropping, which discards image content, inpainting,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Tianhao Zhou , Haipeng Li , Ziyi Wang , Ao Luo , Chen-Lin Zhang , Jiajun Li , Bing Zeng , Shuaicheng Liu

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież

Segmentation of organs of interest in medical CT images is beneficial for diagnosis of diseases. Though recent methods based on Fully Convolutional Neural Networks (F-CNNs) have shown success in many segmentation tasks, fusing features from…

Artificial Intelligence · Computer Science 2024-05-10 Yanli Yuan , Bingbing Wang , Chuan Zhang , Jingyi Xu , Ximeng Liu , Liehuang Zhu

Magnetic Resonance Imaging (MRI) is a crucial diagnostic tool, but high-resolution scans are often slow and expensive due to extensive data acquisition requirements. Traditional MRI reconstruction methods aim to expedite this process by…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Emmanuelle Bourigault , Abdullah Hamdi , Amir Jamaludin

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

Incremental brain tumor segmentation is critical for models that must adapt to evolving clinical datasets without retraining on all prior data. However, catastrophic forgetting, where models lose previously acquired knowledge, remains a…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Sashank Makanaboyina

Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Delin An , Pan Du , Jian-Xun Wang , Chaoli Wang

Multimodal medical image fusion is a crucial task that combines complementary information from different imaging modalities into a unified representation, thereby enhancing diagnostic accuracy and treatment planning. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Meng Zhou , Yuxuan Zhang , Xiaolan Xu , Jiayi Wang , Farzad Khalvati

Medical image segmentation can provide a reliable basis for further clinical analysis and disease diagnosis. The performance of medical image segmentation has been significantly advanced with the convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Ruxin Wang , Shuyuan Chen , Chaojie Ji , Jianping Fan , Ye Li

Pancreas segmentation in medical image processing is a persistent challenge due to its small size, low contrast against adjacent tissues, and significant topological variations. Traditional level set methods drive boundary evolution using…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Yue Gou , Fanghui Song , Yuming Xing , Shengzhu Shi , Zhichang Guo , Boying Wu

In clinical practice, tri-modal medical image fusion, compared to the existing dual-modal technique, can provide a more comprehensive view of the lesions, aiding physicians in evaluating the disease's shape, location, and biological…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yushen Xu , Xiaosong Li , Yuchan Jie , Haishu Tan

Accurately segmenting blood vessels in retinal fundus images is crucial in the early screening, diagnosing, and evaluating some ocular diseases, yet it poses a nontrivial uncertainty for the segmentation task due to various factors such as…

Image and Video Processing · Electrical Eng. & Systems 2023-06-29 Yuanyuan Peng , Pengpeng Luan , Zixu Zhang
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