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This paper proposes a multi-shell sampling scheme and corresponding transforms for the accurate reconstruction of the diffusion signal in diffusion MRI by expansion in the spherical polar Fourier (SPF) basis. The sampling scheme uses an…

Computer Vision and Pattern Recognition · Computer Science 2017-05-15 Alice P. Bates , Zubair Khalid , Jason D. McEwen , Rodney A. Kennedy

We introduce wave encoded acquisition and reconstruction techniques for highly accelerated echo planar imaging (EPI) with reduced g-factor penalty and image artifacts. Wave-EPI involves playing sinusoidal gradients during the EPI readout…

Image and Video Processing · Electrical Eng. & Systems 2021-06-04 Jaejin Cho , Congyu Liao , Qiyuan Tian , Zijing Zhang , Jinmin Xu , Wei-Ching Lo , Benedikt A. Poser , V. Andrew Stenger , Jason Stockmann , Kawin Setsompop , Berkin Bilgic

Diffusion-weighted magnetic resonance imaging (D-MRI) is an in-vivo and non-invasive imaging technology to probe anatomical architectures of biological samples. The anatomy of white matter fiber tracts in the brain can be revealed to help…

Applications · Statistics 2023-05-18 Jilei Yang , Seungyong Hwang , Jie Peng

In-vivo examination of the physical connectivity of axonal projections through the white matter of the human brain is made possible by diffusion weighted magnetic resonance imaging (dMRI) Analysis of dMRI commonly considers derived scalar…

Image and Video Processing · Electrical Eng. & Systems 2019-12-03 Haraldur T. Hallgrimsson , Richika Sharan , Scott T. Grafton , Ambuj K. Singh

Visual perception relies on inference of 3D scene properties such as shape, pose, and lighting. To understand how visual sensory neurons enable robust perception, it is crucial to characterize their selectivity to such physically…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Pavithra Elumalai , Mohammad Bashiri , Goirik Chakrabarty , Suhas Shrinivasan , Fabian H. Sinz

Purpose: In diffusion MRI (dMRI), the volumetric and bundle analyses of whole-brain tissue microstructure and connectivity can be severely impeded by an incomplete field-of-view (FOV). This work aims to develop a method for imputing the…

Diffusion models have demonstrated strong generative capabilities across scientific domains, but often produce outputs that violate physical laws. We propose a new perspective by framing physics-informed generation as a sparse reward…

Machine Learning · Computer Science 2025-09-26 Mingze Yuan , Pengfei Jin , Na Li , Quanzheng Li

We review, systematize and discuss models of diffusion in neuronal tissue, by putting them into an overarching physical context of coarse-graining over an increasing diffusion length scale. From this perspective, we view research on…

Biological Physics · Physics 2018-04-20 Dmitry S. Novikov , Els Fieremans , Sune N. Jespersen , Valerij G. Kiselev

This paper explores the reconstruction of a space-dependent parameter in inverse diffusion problems, proposing a shape-optimization-based approach. We consider a Robin boundary condition, physically motivated in diffuse optical tomography…

Numerical Analysis · Mathematics 2026-01-27 Manabu Machida , Hirofumi Notsu , Julius Fergy Tiongson Rabago

It can be challenging to identify brain MRI anomalies using supervised deep-learning techniques due to anatomical heterogeneity and the requirement for pixel-level labeling. Unsupervised anomaly detection approaches provide an alternative…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Hasan Iqbal , Umar Khalid , Jing Hua , Chen Chen

Accurate dose distribution prediction is crucial in the radiotherapy planning. Although previous methods based on convolutional neural network have shown promising performance, they have the problem of over-smoothing, leading to prediction…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Xin Liao , Zhenghao Feng , Jianghong Xiao , Xingchen Peng , Yan Wang

Diffusion models are the current state-of-the-art for solving inverse problems in imaging. Their impressive generative capability allows them to approximate sampling from a prior distribution, which alongside a known likelihood function…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Samuel W. Remedios , Zhangxing Bian , Shuwen Wei , Aaron Carass , Jerry L. Prince , Blake E. Dewey

Modern diffusion MRI sequences commonly acquire a large number of volumes with diffusion sensitization gradients of differing strengths or directions. Such sequences rely on echo-planar imaging (EPI) to achieve reasonable scan duration.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-06 Antoine Legouhy , Ross Callaghan , Whitney Stee , Philippe Peigneux , Hojjat Azadbakht , Hui Zhang

Optical coherence tomography (OCT) is a powerful and noninvasive method for retinal imaging. In this paper, we introduce a fast segmentation method based on a new variant of spectral graph theory named diffusion maps. The research is…

Computer Vision and Pattern Recognition · Computer Science 2012-10-09 Raheleh Kafieh , Hossein Rabbani , Michael D. Abramoff , Milan Sonka

Lensless fiber endomicroscope is an emerging tool for in-vivo microscopic imaging, where quantitative phase imaging (QPI) can be utilized as a label-free method to enhance image contrast. However, existing single-shot phase reconstruction…

Accurate local fiber orientation distribution (FOD) modeling based on diffusion magnetic resonance imaging (dMRI) capable of resolving complex fiber configurations benefits from specific acquisition protocols that sample a high number of…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Oeslle Lucena , Sjoerd B. Vos , Vejay Vakharia , John Duncan , Keyoumars Ashkan , Rachel Sparks , Sebastien Ourselin

Intra-voxel models of the diffusion signal are essential for interpreting organization of the tissue environment at micrometer level with data at millimeter resolution. Recent advances in data driven methods have enabled direct compari-son…

We present a microstructure imaging technique for estimating compartment-specific T2 and T2* simultaneously in the human brain. Microstructure imaging with diffusion MRI (dMRI) has enabled the modelling of intra-neurite and extra-neurite…

Medical Physics · Physics 2024-08-21 Ting Gong , Merlin J. Fair , Kawin Setsompop , Hui Zhang

Diffusion-weighted magnetic resonance imaging (dMRI) is the only non-invasive tool for studying white matter tracts and structural connectivity of the brain. These assessments rely heavily on tractography techniques, which reconstruct…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Weide Liu , Camilo Calixto , Simon K. Warfield , Davood Karimi

Confocal histology provides an opportunity to establish intra-voxel fiber orientation distributions that can be used to quantitatively assess the biological relevance of diffusion weighted MRI models, e.g., constrained spherical…

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