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Diffusion models have shown great promise in medical image denoising and reconstruction, but their application to Positron Emission Tomography (PET) imaging remains limited by tracer-specific contrast variability and high computational…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Fumio Hashimoto , Kuang Gong

Low Dose Computed Tomography (LDCT) has offered tremendous benefits in radiation restricted applications, but the quantum noise as resulted by the insufficient number of photons could potentially harm the diagnostic performance. Current…

Computer Vision and Pattern Recognition · Computer Science 2019-03-06 Xin Yi , Paul Babyn

Large scale image super-resolution is a challenging computer vision task, since vast information is missing in a highly degraded image, say for example forscale x16 super-resolution. Diffusion models are used successfully in recent years in…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Chun-Chuen Hui , Wan-Chi Siu , Ngai-Fong Law

Sparse-view computed tomography (CT) can be used to reduce radiation dose greatly but is suffers from severe image artifacts. Recently, the deep learning based method for sparse-view CT reconstruction has attracted a major attention.…

Image and Video Processing · Electrical Eng. & Systems 2022-11-21 Wenjun Xia , Wenxiang Cong , Ge Wang

Deep learning has proven to be important for CT image denoising. However, such models are usually trained under supervision, requiring paired data that may be difficult to obtain in practice. Diffusion models offer unsupervised means of…

While diffusion models demonstrate strong generative capabilities in image restoration (IR) tasks, their complex architectures and iterative processes limit their practical application compared to mainstream reconstruction-based general…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Xin Lu , Xueyang Fu , Jie Xiao , Zihao Fan , Yurui Zhu , Zheng-Jun Zha

Three-dimensional microscopy is often limited by anisotropic spatial resolution, resulting in lower axial resolution than lateral resolution. Current State-of-The-Art (SoTA) isotropic reconstruction methods utilizing deep neural networks…

Image and Video Processing · Electrical Eng. & Systems 2023-06-22 Mingjie Pan , Yulu Gan , Fangxu Zhou , Jiaming Liu , Aimin Wang , Shanghang Zhang , Dawei Li

Three-dimensional (3D) medical image enhancement, including denoising and super-resolution, is critical for clinical diagnosis in CT, PET, and MRI. Although diffusion models have shown remarkable success in 2D medical imaging, scaling them…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Hongxu Jiang , Fei Li , Boxiao Yu , Ying Zhang , Kaleb Smith , Kuang Gong , Wei Shao

Training deep neural networks has become a common approach for addressing image restoration problems. An alternative for training a "task-specific" network for each observation model is to use pretrained deep denoisers for imposing only the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Tomer Garber , Tom Tirer

Given the potential X-ray radiation risk to the patient, low-dose CT has attracted a considerable interest in the medical imaging field. The current main stream low-dose CT methods include vendor-specific sinogram domain filtration and…

Medical Physics · Physics 2017-12-12 Hu Chen , Yi Zhang , Mannudeep K. Kalra , Feng Lin , Yang Chen , Peixi Liao , Jiliu Zhou , Ge Wang

Text-to-image diffusion model is a popular paradigm that synthesizes personalized images by providing a text prompt and a random Gaussian noise. While people observe that some noises are ``golden noises'' that can achieve better text-image…

Machine Learning · Computer Science 2025-07-18 Zikai Zhou , Shitong Shao , Lichen Bai , Shufei Zhang , Zhiqiang Xu , Bo Han , Zeke Xie

Deep learning (DL) methods typically require large datasets to effectively learn data distributions. However, in the medical field, data is often limited in quantity, and acquiring labeled data can be costly. To mitigate this data scarcity,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Marina Domínguez , Yordanka Velikova , Nassir Navab , Mohammad Farid Azampour

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Diffusion models (DMs) are a powerful generative framework that have attracted significant attention in recent years. However, the high computational cost of training DMs limits their practical applications. In this paper, we start with a…

Machine Learning · Computer Science 2024-04-12 Tianshuo Xu , Peng Mi , Ruilin Wang , Yingcong Chen

Denosing diffusion model, as a generative model, has received a lot of attention in the field of image generation recently, thanks to its powerful generation capability. However, diffusion models have not yet received sufficient research in…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 ZiHan Cao , ShiQi Cao , Xiao Wu , JunMing Hou , Ran Ran , Liang-Jian Deng

Computed tomography is a widely used imaging modality with applications ranging from medical imaging to material analysis. One major challenge arises from the lack of scanning information at certain angles, resulting in distortion or…

Snapshot compressive spectral imaging reconstruction aims to reconstruct three-dimensional spatial-spectral images from a single-shot two-dimensional compressed measurement. Existing state-of-the-art methods are mostly based on deep…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Zongliang Wu , Ruiying Lu , Ying Fu , Xin Yuan

Diffusion models have recently received a surge of interest due to their impressive performance for image restoration, especially in terms of noise robustness. However, existing diffusion-based methods are trained on a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Yuchun Miao , Lefei Zhang , Liangpei Zhang , Dacheng Tao

Pathological brain lesions exhibit diverse appearance in brain images, in terms of intensity, texture, shape, size, and location. Comprehensive sets of data and annotations are difficult to acquire. Therefore, unsupervised anomaly detection…