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A linear structural equation model relates random variables of interest and corresponding Gaussian noise terms via a linear equation system. Each such model can be represented by a mixed graph in which directed edges encode the linear…

Statistics Theory · Mathematics 2012-10-04 Rina Foygel , Jan Draisma , Mathias Drton

This paper presents a method for investigating, through an automatic procedure, the (lack of) identifiability of parametrized dynamical models. This method takes into account constraints on parameters and returns parameters whose…

Dynamical Systems · Mathematics 2016-10-11 Nathalie Verdière , Sébastien Orange

We introduce a subclass of Lie symmetries, called parameter-state symmetries, to analyse the local structural identifiability and observability of mechanistic models consisting of state-dependent ODEs with observed outputs. These symmetries…

Dynamical Systems · Mathematics 2026-03-13 Johannes G. Borgqvist , Alexander P. Browning , Fredrik Ohlsson , Ruth E. Baker

Parameter inference and uncertainty quantification are important steps when relating mathematical models to real-world observations, and when estimating uncertainty in model predictions. However, methods for doing this can be…

Quantitative Methods · Quantitative Biology 2025-08-27 Michael J. Plank , Matthew J. Simpson

The linear spline growth model (LSGM), which approximates complex patterns using at least two linear segments, is a popular tool for examining nonlinear change patterns. Among such models, the linear-linear piecewise change pattern is the…

Methodology · Statistics 2022-05-10 Jin Liu , Robert A. Perera , Le Kang , Robert M. Kirkpatrick , Roy T. Sabo

Linear structural equation models relate the components of a random vector using linear interdependencies and Gaussian noise. Each such model can be naturally associated with a mixed graph whose vertices correspond to the components of the…

This paper studies the problems of identifiability and estimation in high-dimensional nonparametric latent structure models. We introduce an identifiability theorem that generalizes existing conditions, establishing a unified framework…

Statistics Theory · Mathematics 2025-08-06 Yichen Lyu , Pengkun Yang

To comprehend complex systems with multiple states, it is imperative to reveal the identity of these states by system outputs. Nevertheless, the mathematical models describing these systems often exhibit nonlinearity so that render the…

Machine Learning · Computer Science 2023-07-04 Guangtao Zhang , Yiting Duan , Guanyu Pan , Qijing Chen , Huiyu Yang , Zhikun Zhang

In this paper we investigate undirected discrete graphical tree models when all the variables in the system are binary, where leaves represent the observable variables and where all the inner nodes are unobserved. A novel approach based on…

Statistics Theory · Mathematics 2012-03-06 Piotr Zwiernik , Jim Q. Smith

The problem of identifiability of finite mixtures of finite product measures is studied. A mixture model with $K$ mixture components and $L$ observed variables is considered, where each variable takes its value in a finite set with…

Statistics Theory · Mathematics 2018-07-17 Behrooz Tahmasebi , Seyed Abolfazl Motahari , Mohammad Ali Maddah-Ali

Mixtures of ranking models are standard tools for ranking problems. However, even the fundamental question of parameter identifiability is not fully understood: the identifiability of a mixture model with two Bradley-Terry-Luce (BTL)…

Machine Learning · Computer Science 2022-05-25 Xiaomin Zhang , Xucheng Zhang , Po-Ling Loh , Yingyu Liang

Mathematical modelling has become an established tool for studying the dynamics of biological systems. Current applications range from building models that reproduce quantitative data to identifying systems with predefined qualitative…

Molecular Networks · Quantitative Biology 2018-02-07 Carsten Conradi , Elisenda Feliu , Maya Mincheva , Carsten Wiuf

Phenomenological models are highly effective tools for forecasting disease dynamics using real world data, particularly in scenarios where detailed knowledge of disease mechanisms is limited. However, their reliability depends on the model…

Quantitative Methods · Quantitative Biology 2025-03-31 Yuganthi R. Liyanage , Gerardo Chowell , Gleb Pogudin , Necibe Tuncer

Covarion models of character evolution describe inhomogeneities in substitution processes through time. In phylogenetics, such models are used to describe changing functional constraints or selection regimes during the evolution of…

Populations and Evolution · Quantitative Biology 2008-05-27 Elizabeth S. Allman , John A. Rhodes

Structural global parameter identifiability indicates whether one can determine a parameter's value from given inputs and outputs in the absence of noise. If a given model has parameters for which there may be infinitely many values, such…

Symbolic Computation · Computer Science 2022-04-05 Ilia Ilmer , Alexey Ovchinnikov , Gleb Pogudin , Pedro Soto

Probabilistic models often have parameters that can be translated, scaled, permuted, or otherwise transformed without changing the model. These symmetries can lead to strong correlation and multimodality in the posterior distribution over…

Machine Learning · Statistics 2013-12-20 Robert Nishihara , Thomas Minka , Daniel Tarlow

Dynamic models of biochemical networks typically consist of sets of non-linear ordinary differential equations involving states (concentrations or amounts of the components of the network) and parameters describing the reaction kinetics.…

Molecular Networks · Quantitative Biology 2014-03-07 Oana-Teodora Chis , Julio R. Banga , Eva Balsa-Canto

This paper considers (partial) identification of a variety of counterfactual parameters in binary response models with possibly endogenous regressors. Our framework allows for nonseparable index functions with multi-dimensional latent…

Econometrics · Economics 2022-07-26 Jiaying Gu , Thomas M. Russell

Log-linear models are typically fitted to contingency table data to describe and identify the relationship between different categorical variables. However, the data may include observed zero cell entries. The presence of zero cell entries…

Methodology · Statistics 2022-12-01 Serveh Sharifi Far , Michail Papathomas , Ruth King

Parametric linear systems are linear systems of equations in which some symbolic parameters, that is, symbols that are not considered to be candidates for elimination or solution in the course of analyzing the problem, appear in the…

Rings and Algebras · Mathematics 2025-09-01 Robert M. Corless , Mark Giesbrecht , Leili Rafiee Sevyeri , B. David Saunders
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