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A deep neural network (DNN) that can reliably model muscle responses from corresponding brain stimulation has the potential to increase knowledge of coordinated motor control for numerous basic science and applied use cases. Such cases…

Markov Chain Monte Carlo (MCMC) techniques are now widely used for cosmological parameter estimation. Chains are generated to sample the posterior probability distribution obtained following the Bayesian approach. An important issue is how…

Estimation in the deformable template model is a big challenge in image analysis. The issue is to estimate an atlas of a population. This atlas contains a template and the corresponding geometrical variability of the observed shapes. The…

Statistics Theory · Mathematics 2013-09-09 Stéphanie Allassonniere , Estelle Kuhn

In the 20+ years of Doppler observations of stars, scientists have uncovered a diverse population of extrasolar multi-planet systems. A common technique for characterizing the orbital elements of these planets is Markov chain Monte Carlo…

Earth and Planetary Astrophysics · Physics 2015-06-18 Benjamin E. Nelson , Eric B. Ford , Matthew J. Payne

Marker-based Optical Motion Capture (OMC) paired with biomechanical modeling is currently considered the most precise and accurate method for measuring human movement kinematics. However, combining differentiable biomechanical modeling with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Tim Unger , Arash Sal Moslehian , J. D. Peiffer , Johann Ullrich , Roger Gassert , Olivier Lambercy , R. James Cotton , Chris Awai Easthope

Markov Chain Monte Carlo (MCMC) algorithms are often used for approximate inference inside learning, but their slow mixing can be difficult to diagnose and the approximations can seriously degrade learning. To alleviate these issues, we…

Machine Learning · Computer Science 2015-02-25 Jacob Steinhardt , Percy Liang

Clinical assessments for neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), continue to rely on subjective measures to monitor treatment response and disease progression. We introduce a…

Accurate parameter identification of a subject-specific human musculoskeletal model is crucial to the development of safe and reliable physically collaborative robotic systems, for instance, assistive exoskeletons. Electromyography…

Robotics · Computer Science 2025-09-30 Philip Sanderink , Yingfan Zhou , Shuzhen Luo , Cheng Fang

There is a tension between robustness and efficiency when designing Markov chain Monte Carlo (MCMC) sampling algorithms. Here we focus on robustness with respect to tuning parameters, showing that more sophisticated algorithms tend to be…

Computation · Statistics 2020-05-12 Samuel Livingstone , Giacomo Zanella

Longitudinal biomedical studies monitor individuals over time to capture dynamics in brain development, disease progression, and treatment effects. However, estimating trajectories of brain biomarkers is challenging due to biological…

Machine Learning · Computer Science 2025-04-15 Vasiliki Tassopoulou , Haochang Shou , Christos Davatzikos

We propose a new class of structured methods for Monte Carlo (MC) sampling, called DPPMC, designed for high-dimensional nonisotropic distributions where samples are correlated to reduce the variance of the estimator via determinantal point…

Machine Learning · Computer Science 2019-05-31 Krzysztof Choromanski , Aldo Pacchiano , Jack Parker-Holder , Yunhao Tang

A novel adaptive Markov chain Monte Carlo algorithm is presented. The algorithm utilizes sparsity in the partial correlation structure of a density to efficiently estimate the covariance matrix through the Cholesky factor of the precision…

Computation · Statistics 2016-02-09 Jonas Wallin , David Bolin

There has been much recent interest in adapting undersampled trajectories in MRI based on training data. In this work, we propose a novel patient-adaptive MRI sampling algorithm based on grouping scans within a training set. Scan-adaptive…

Image and Video Processing · Electrical Eng. & Systems 2026-02-26 Siddhant Gautam , Angqi Li , Saiprasad Ravishankar

We develop a novel advanced Particle Markov chain Monte Carlo algorithm that is capable of sampling from the posterior distribution of non-linear state space models for both the unobserved latent states and the unknown model parameters. We…

Methodology · Statistics 2015-03-17 Gareth W. Peters , Geoff R. Hosack , Keith R. Hayes

Random Walk Metropolis Hastings (RWMH) algorithm, is quite inefficient in high dimensions because of its abysmally slow acceptance rate. The slow acceptance rate results from the fact that RWMH separately updates each coordinate of the…

Methodology · Statistics 2014-08-29 Kushal K. Dey , Sourabh Bhattacharya

Markov chain Monte Carlo (MCMC) methods are ubiquitous tools for simulation-based inference in many fields but designing and identifying good MCMC samplers is still an open question. This paper introduces a novel MCMC algorithm, namely,…

We propose a general method for optimally approximating an arbitrary matrix $\mathbf{M}$ by a structured matrix $\mathbf{T}$ (circulant, Toeplitz/Hankel, etc.) and examine its use for estimating the spectra of genomic linkage disequilibrium…

Applications · Statistics 2024-09-10 Chris Salahub , Jeffrey Uhlmann

Markov Chain Monte Carlo (MCMC) methods are employed to sample from a given distribution of interest, whenever either the distribution does not exist in closed form, or, if it does, no efficient method to simulate an independent sample from…

Computation · Statistics 2008-07-22 Ioana A. Cosma , Masoud Asgharian

Muscular dystrophy (MD) describes generalized progressive muscular weakness due to the wasting of muscle fibers. The progression of the disease is affected by known immunological and mechanical factors, and possibly other unknown…

Quantitative Methods · Quantitative Biology 2016-10-31 Amanda N. Cameron , Matthew T. Houston , Juan B. Gutierrez

We present a novel algorithm that is based on a Bayesian Markov Chain Monte Carlo (MCMC) technique for performing robust profile analysis of a data cube from either single-dish or interferometric radio telescopes. It fits a set of models…

Astrophysics of Galaxies · Physics 2019-05-22 Se-Heon Oh , Lister Staveley-Smith , Bi-Qing For
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