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Quantifying the dynamics of tumor burden reveals useful information about cancer evolution concerning treatment effects and drug resistance, which play a crucial role in advancing model-informed drug developments (MIDD) towards personalized…

Other Quantitative Biology · Quantitative Biology 2023-01-10 Nam Nguyen , Kwang-Cheng Chen

Identification of cancer driver genes is fundamental for the development of targeted therapeutic interventions. The integration of mutational profiles with protein-protein interaction (PPI) networks offers a promising avenue for their…

Quantum Physics · Physics 2025-11-05 Patricia Marques , Andreas Wichert , Duarte Magano , Bruno Coutinho

Quantum machine learning has emerged as a promising approach to improve feature extraction and classification tasks in high-dimensional data domains such as medical imaging. In this work, we present a hybrid Quantum-Classical Convolutional…

Quantum Physics · Physics 2026-05-12 Ece Yurtseven

The success of the self-attention mechanism in classical machine learning models has inspired the development of quantum analogs aimed at reducing computational overhead. Self-attention integrates learnable query and key matrices to…

Accurate classification of brain tumors from MRI scans is critical for effective treatment planning. This study presents a Hybrid Quantum Convolutional Neural Network (HQCNN) that integrates quantum feature-encoding circuits with depth-wise…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Muhammad Al-Zafar Khan , Abdullah Al Omar Galib , Nouhaila Innan , Mohamed Bennai

Determining the primary site of origin for metastatic tumors is one of the open problems in cancer care because the efficacy of treatment often depends on the cancer tissue of origin. Classification methods that can leverage tumor genomic…

Genomics · Quantitative Biology 2019-11-19 Alena Harley

Machine learning has been increasingly utilized in the field of biomedical research to accelerate the drug discovery process. In recent years, the emergence of quantum computing has been followed by extensive exploration of quantum machine…

Quantum machine learning is receiving significant attention currently, but its usefulness in comparison to classical machine learning techniques for practical applications remains unclear. However, there are indications that certain quantum…

Quantum-classical Hybrid Machine Learning (QHML) models are recognized for their robust performance and high generalization ability even for relatively small datasets. These qualities offer unique advantages for anti-cancer drug response…

Machine Learning · Computer Science 2025-05-16 Takafumi Ito , Lysenko Artem , Tatsuhiko Tsunoda

QCAAPatchTF is a quantum attention network integrated with an advanced patch-based transformer, designed for multivariate time series forecasting, classification, and anomaly detection. Leveraging quantum superpositions, entanglement, and…

Machine Learning · Computer Science 2025-04-02 Sanjay Chakraborty , Fredrik Heintz

Hybrid quantum-classical machine learning offers a promising direction for advancing automated quality control in industrial settings. In this study, we investigate two hybrid quantum-classical approaches for classifying defects in…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Akshaya Srinivasan , Xiaoyin Cheng , Jianming Yi , Alexander Geng , Desislava Ivanova , Andreas Weinmann , Ali Moghiseh

Cancer is one of the leading causes of death worldwide. It is caused by a variety of genetic mutations, which makes every instance of the disease unique. Since chemotherapy can have extremely severe side effects, each patient requires a…

Recent advancements in Quantum Computing and Machine Learning have increased attention to Quantum Machine Learning (QML), which aims to develop machine learning models by exploiting the quantum computing paradigm. One of the widely used…

Machine Learning · Computer Science 2026-04-10 Antonio Tudisco , Andrea Marchesin , Maurizio Zamboni , Mariagrazia Graziano , Giovanna Turvani

Defining and separating cancer subtypes is essential for facilitating personalized therapy modality and prognosis of patients. The definition of subtypes has been constantly recalibrated as a result of our deepened understanding. During…

Machine Learning · Computer Science 2022-07-21 Zheng Chen , Ziwei Yang , Lingwei Zhu , Guang Shi , Kun Yue , Takashi Matsubara , Shigehiko Kanaya , MD Altaf-Ul-Amin

Quantum computing offers new opportunities for addressing complex classification tasks in biomedical applications. This study investigates two quantum machine learning models-the Quantum Support Vector Machine (QSVM) and the Variational…

Quantum Physics · Physics 2025-04-16 Chi-Chuan Hwang , Cheng-Fang Su , Yi-Ang Hong

Accurate and efficient prediction of electronic wavefunctions is central to ab initio molecular dynamics (AIMD) and electronic structure theory. However, conventional ab initio methods require self-consistent optimization of electronic…

Chemical Physics · Physics 2025-11-12 Yanxian Tao , Lingyun Wan , Xiongzhi Zeng , Yingdi Jin , Jie Liu , Zhenyu Li , Jinlong Yang

Quantum phase transitions in many-body systems are fundamentally characterized by complex correlation structures, which pose computational challenges for conventional methods in large systems. To address this, we propose a hybrid…

Quantum Physics · Physics 2026-02-03 Jin-Long Chen , Xin Li , Zhang-Qi Yin

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

The complexity of biological systems, governed by molecular interactions across hierarchical scales, presents a challenge for computational modeling. While advances in multiomic profiling have enabled precise measurements of biological…

Quantum Physics · Physics 2025-06-18 Michael Kubal , Sonika Johri

The ability to accurately classify disease subtypes is of vital importance, especially in oncology where this capability could have a life saving impact. Here we report a classification between two subtypes of non-small cell lung cancer,…

Machine Learning · Statistics 2018-10-30 Siddhant Jain , Jalal Ziauddin , Paul Leonchyk , Joseph Geraci