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Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits and heterogeneity of multi-sources genomics data pose…

Computation and Language · Computer Science 2025-11-25 Yanjun Lyu , Zihao Wu , Lu Zhang , Jing Zhang , Yiwei Li , Wei Ruan , Zhengliang Liu , Zeyu Zhang , Xiang Li , Rongjie Liu , Chao Huang , Wentao Li , Tianming Liu , Dajiang Zhu

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

Recent development in Retrieval-Augmented Large Language Models (LLMs) have shown great promise in biomedical applications. How ever, a critical gap persists in reliably evaluating their curation ability the process by which models select…

Computation and Language · Computer Science 2025-08-07 Hanmeng Zhong , Linqing Chen , Wentao Wu , Weilei Wang

Healthcare systems continuously generate vast amounts of electronic health records (EHRs), commonly stored in the Fast Healthcare Interoperability Resources (FHIR) standard. Despite the wealth of information in these records, their…

Computation and Language · Computer Science 2025-01-24 Sara Kothari , Ayush Gupta

Pre-trained Language Models (PLMs) are integral to many modern natural language processing (NLP) systems. Although multilingual models cover a wide range of languages, they often grapple with challenges like high inference costs and a lack…

Computation and Language · Computer Science 2024-07-19 Murtadha Ahmed , Saghir Alfasly , Bo Wen , Jamaal Qasem , Mohammed Ahmed , Yunfeng Liu

Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and…

Computation and Language · Computer Science 2025-10-14 Amin Dada , Marie Bauer , Amanda Butler Contreras , Osman Alperen Koraş , Constantin Marc Seibold , Kaleb E Smith , Jens Kleesiek

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

The emergence of Large Language Models (LLMs) has fundamentally transformed natural language processing, making them indispensable across domains ranging from conversational systems to scientific exploration. However, their pre-trained…

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

This study evaluates the performance of several Large Language Models (LLMs) on MedRedQA, a dataset of consumer-based medical questions and answers by verified experts extracted from the AskDocs subreddit. While LLMs have shown proficiency…

Computation and Language · Computer Science 2025-01-03 Moaiz Abrar , Yusuf Sermet , Ibrahim Demir

Religious teachings can sometimes be complex and challenging to grasp, but chatbots can serve as effective assistants in this domain. Large Language Model (LLM) based chatbots, powered by Natural Language Processing (NLP), can connect…

Computation and Language · Computer Science 2025-12-10 Ahmet Yusuf Alan , Enis Karaarslan , Omer Aydin

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

Large language models (LLMs) are powerful artificial intelligence (AI) tools transforming how research is conducted. However, their use in research has been met with skepticism, due to concerns about hallucinations, biases and potential…

Artificial Intelligence · Computer Science 2025-07-08 Ruian Ke , Ruy M. Ribeiro

Large-scale pre-trained language models (PLMs) such as BERT have recently achieved great success and become a milestone in natural language processing (NLP). It is now the consensus of the NLP community to adopt PLMs as the backbone for…

Computation and Language · Computer Science 2023-03-21 Nan Hu , Yike Wu , Guilin Qi , Dehai Min , Jiaoyan Chen , Jeff Z. Pan , Zafar Ali

Despite their impressive performance on diverse tasks, large language models (LMs) still struggle with tasks requiring rich world knowledge, implying the limitations of relying solely on their parameters to encode a wealth of world…

Computation and Language · Computer Science 2023-07-04 Alex Mallen , Akari Asai , Victor Zhong , Rajarshi Das , Daniel Khashabi , Hannaneh Hajishirzi

In recent years, Large Language Models (LLMs) have become widely used in medical applications, such as clinical decision support, medical education, and medical question answering. Yet, these models are often English-centric, limiting their…

Computation and Language · Computer Science 2026-02-06 Chaimae Abouzahir , Congbo Ma , Nizar Habash , Farah E. Shamout

Large Language Models (LLMs) such as GPT developed by OpenAI, have already shown astonishing results, introducing quick changes in our society. This has been intensified by the release of ChatGPT which allows anyone to interact in a simple…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Ivan DeAndres-Tame , Ruben Tolosana , Ruben Vera-Rodriguez , Aythami Morales , Julian Fierrez , Javier Ortega-Garcia

The applications of large language models (LLMs) in various biological domains have been explored recently, but their reasoning ability in complex biological systems, such as pathways, remains underexplored, which is crucial for predicting…

Machine Learning · Computer Science 2025-07-23 Haiteng Zhao , Chang Ma , Fangzhi Xu , Lingpeng Kong , Zhi-Hong Deng

The exponential growth of biomedical texts such as biomedical literature and electronic health records (EHRs), poses a significant challenge for clinicians and researchers to access clinical information efficiently. To tackle this…

Computation and Language · Computer Science 2023-07-17 Qianqian Xie , Zheheng Luo , Benyou Wang , Sophia Ananiadou

Large language models (LLMs) are deep learning algorithms being used to perform natural language processing tasks in various fields, from social sciences to finance and biomedical sciences. Developing and training a new LLM can be very…

General Finance · Quantitative Finance 2024-01-23 Valentina Aparicio , Daniel Gordon , Sebastian G. Huayamares , Yuhuai Luo