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With the rising complexity of numerous novel applications that serve our modern society comes the strong need to design efficient computing platforms. Designing efficient hardware is, however, a complex multi-objective problem that deals…

Hardware Architecture · Computer Science 2023-04-11 Alireza Ghaffari , Masoud Asgharian , Yvon Savaria

Developing complex, reliable advanced accelerators requires a coordinated, extensible, and comprehensive approach in modeling, from source to the end of beam lifetime. We present highlights in Exascale Computing to scale accelerator…

This work introduces ParAMS -- a versatile Python package that aims to make parameterization workflows in computational chemistry and physics more accessible, transparent and reproducible. We demonstrate how ParAMS facilitates the parameter…

Chemical Physics · Physics 2021-05-18 Leonid Komissarov , Robert Rüger , Matti Hellström , Toon Verstraelen

Computational workflows are a common class of application on supercomputers, yet the loosely coupled and heterogeneous nature of workflows often fails to take full advantage of their capabilities. We created Colmena to leverage the massive…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-08-27 Logan Ward , J. Gregory Pauloski , Valerie Hayot-Sasson , Yadu Babuji , Alexander Brace , Ryan Chard , Kyle Chard , Rajeev Thakur , Ian Foster

The Particle-In-Cell (PIC) method is a computational technique widely used in plasma physics to model plasmas at the kinetic level. In this work, we present our effort to prepare the semi-implicit energy-conserving PIC code ECsim for…

Tensor processing units (TPUs) are one of the most well-known machine learning (ML) accelerators utilized at large scale in data centers as well as in tiny ML applications. TPUs offer several improvements and advantages over conventional ML…

Hardware Architecture · Computer Science 2024-07-12 Mohammed Elbtity , Peyton Chandarana , Ramtin Zand

Constructing datasets representative of the target domain is essential for training effective machine learning models. Active learning (AL) is a promising method that iteratively extends training data to enhance model performance while…

For many macromolecular systems the accurate sampling of the relevant regions on the potential energy surface cannot be obtained by a single, long Molecular Dynamics (MD) trajectory. New approaches are required to promote more efficient…

Computational Engineering, Finance, and Science · Computer Science 2016-06-02 Vivekanandan Balasubramanian , Iain Bethune , Ardita Shkurti , Elena Breitmoser , Eugen Hruska , Cecilia Clementi , Charles Laughton , Shantenu Jha

The Portable Extensible Toolkit for Scientific computation (PETSc) library delivers scalable solvers for nonlinear time-dependent differential and algebraic equations and for numerical optimization.The PETSc design for performance…

An alias table is a data structure that allows for efficiently drawing weighted random samples in constant time and can be constructed in linear time. The PSA algorithm by H\"ubschle-Schneider and Sanders is able to construct alias tables…

Data Structures and Algorithms · Computer Science 2022-05-24 Hans-Peter Lehmann , Lorenz Hübschle-Schneider , Peter Sanders

The prediction of material properties through electronic-structure simulations based on density-functional theory has become routinely common, thanks, in part, to the steady increase in the number and robustness of available simulation…

Software packages like TensorFlow and PyTorch are designed to support linear algebra operations, and their speed and usability determine their success. However, by prioritising speed, they often neglect memory requirements. As a…

Machine Learning · Computer Science 2022-06-29 Artem Artemev , Tilman Roeder , Mark van der Wilk

Detecting packed executables is a critical component of large-scale malware analysis and antivirus engine workflows, as it identifies samples that warrant computationally intensive dynamic unpacking to reveal concealed malicious behavior.…

Cryptography and Security · Computer Science 2025-09-22 Shijia Li , Jiang Ming , Lanqing Liu , Longwei Yang , Ni Zhang , Chunfu Jia

The rapid advancement of machine learning (ML) technologies has driven the development of specialized hardware accelerators designed to facilitate more efficient model training. This paper introduces the CARAML benchmark suite, which is…

Hardware Architecture · Computer Science 2025-03-14 Chelsea Maria John , Stepan Nassyr , Carolin Penke , Andreas Herten

The Large Language Model agent workflow enables the LLM to invoke tool functions to increase the performance on specific scientific domain questions. To tackle large scale of scientific research, it requires access to computing resource and…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-02-19 Heng Ma , Alexander Brace , Carlo Siebenschuh , Greg Pauloski , Ian Foster , Arvind Ramanathan

A common workflow in science and engineering is to (i) setup and deploy large experiments with tasks comprising an application and multiple parameter values; (ii) generate intermediate results; (iii) analyze them; and (iv) reprioritize the…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-10 Bruno Silva , Marco A. S. Netto , Renato L. F. Cunha

Scanning Transmission Electron Microscopy (STEM) coupled with Electron Energy Loss Spectroscopy (EELS) presents a powerful platform for detailed material characterization via rich imaging and spectroscopic data. Modern electron microscopes…

Instrumentation and Detectors · Physics 2024-06-18 Utkarsh Pratiush , Austin Houston , Sergei V Kalinin , Gerd Duscher

We present SPDL (Scalable and Performant Data Loading), an open-source, framework-agnostic library designed for efficiently loading array data to GPU. Data loading is often a bottleneck in AI applications, and is challenging to optimize…

Turning the current experimental plasma accelerator state-of-the-art from a promising technology into mainstream scientific tools depends critically on high-performance, high-fidelity modeling of complex processes that develop over a wide…

Accelerator Physics · Physics 2018-12-26 J. -L. Vay , A. Almgren , J. Bell , L. Ge , D. P. Grote , M. Hogan , O. Kononenko , R. Lehe , A. Myers , C. Ng , J. Park , R. Ryne , O. Shapoval , M. Thevenet , W. Zhang

We present Experiment Automation Agents (EAA), a vision-language-model-driven agentic system designed to automate complex experimental microscopy workflows. EAA integrates multimodal reasoning, tool-augmented action, and optional long-term…

Artificial Intelligence · Computer Science 2026-02-18 Ming Du , Yanqi Luo , Srutarshi Banerjee , Michael Wojcik , Jelena Popovic , Mathew J. Cherukara