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Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

Automating data extraction from full-text randomised controlled trials (RCTs) for meta-analysis remains a significant challenge. This study evaluates the practical performance of three LLMs (Gemini-2.0-flash, Grok-3, GPT-4o-mini) across…

Computation and Language · Computer Science 2025-07-22 Lingbo Li , Anuradha Mathrani , Teo Susnjak

The success of Large Language Models (LLMs) is inherently linked to the availability of vast, diverse, and high-quality data for training and evaluation. However, the growth rate of high-quality data is significantly outpaced by the…

Computation and Language · Computer Science 2024-10-18 Ke Wang , Jiahui Zhu , Minjie Ren , Zeming Liu , Shiwei Li , Zongye Zhang , Chenkai Zhang , Xiaoyu Wu , Qiqi Zhan , Qingjie Liu , Yunhong Wang

Training on model-generated synthetic data is a promising approach for finetuning LLMs, but it remains unclear when it helps or hurts. In this paper, we investigate this question for math reasoning via an empirical study, followed by…

Machine Learning · Computer Science 2024-06-21 Amrith Setlur , Saurabh Garg , Xinyang Geng , Naman Garg , Virginia Smith , Aviral Kumar

Suicidal ideation detection is a vital research area that holds great potential for improving mental health support systems. However, the sensitivity surrounding suicide-related data poses challenges in accessing large-scale, annotated…

Computation and Language · Computer Science 2024-02-06 Hamideh Ghanadian , Isar Nejadgholi , Hussein Al Osman

Generating realistic synthetic populations is essential for agent-based models (ABM) in transportation and urban planning. Current methods face two major limitations. First, many rely on a single dataset or follow a sequential data fusion…

Artificial Intelligence · Computer Science 2026-02-18 Farbod Abbasi , Zachary Patterson , Bilal Farooq

With the advent of AI agents, automatic scientific discovery has become a tenable goal. Many recent works scaffold agentic systems that can perform machine learning research, but don't offer a principled way to train such agents -- and…

Artificial Intelligence · Computer Science 2026-03-19 Ziyang Cai , Harkirat Behl

Effective document reranking is essential for improving search relevance across diverse applications. While Large Language Models (LLMs) excel at reranking due to their deep semantic understanding and reasoning, their high computational…

Computation and Language · Computer Science 2025-10-03 Dimitar Peshevski , Kiril Blazhevski , Martin Popovski , Gjorgji Madjarov

Code-mixing (CM), where speakers blend languages within a single expression, is prevalent in multilingual societies but poses challenges for natural language processing due to its complexity and limited data. We propose using a large…

Computation and Language · Computer Science 2025-10-28 Linda Zeng

Aligning large language models (LLMs) with human values is an increasingly critical step in post-training. Direct Preference Optimization (DPO) has emerged as a simple, yet effective alternative to reinforcement learning from human feedback…

Artificial Intelligence · Computer Science 2025-07-29 Yifan Wang , Runjin Chen , Bolian Li , David Cho , Yihe Deng , Ruqi Zhang , Tianlong Chen , Zhangyang Wang , Ananth Grama , Junyuan Hong

Collecting high-quality training data is essential for fine-tuning Large Language Models (LLMs). However, acquiring such data is often costly and time-consuming, especially for non-English languages such as Italian. Recently, researchers…

Computation and Language · Computer Science 2025-04-01 Fatemeh Mohammadi , Tommaso Romano , Samira Maghool , Paolo Ceravolo

Large language models (LLMs) hold the promise of solving diverse tasks when provided with appropriate natural language prompts. However, prompting often leads models to make predictions with lower accuracy compared to finetuning a model…

Computation and Language · Computer Science 2024-08-13 Chenyang Zhao , Xueying Jia , Vijay Viswanathan , Tongshuang Wu , Graham Neubig

Large Language Models (LLMs) such as GPT-4 and Llama3 have significantly impacted various fields by enabling high-quality synthetic data generation and reducing dependence on expensive human-generated datasets. Despite this, challenges…

Computation and Language · Computer Science 2025-11-18 Yue Huang , Siyuan Wu , Chujie Gao , Dongping Chen , Qihui Zhang , Yao Wan , Tianyi Zhou , Jianfeng Gao , Chaowei Xiao , Lichao Sun , Xiangliang Zhang

Large language models (LLMs) have attracted great attention given their strong performance on a wide range of NLP tasks. In practice, users often expect generated texts to fall within a specific length range, making length controlled…

Computation and Language · Computer Science 2024-06-18 Renlong Jie , Xiaojun Meng , Lifeng Shang , Xin Jiang , Qun Liu

Reinforcement Learning (RL) has been shown to significantly boost reasoning capabilities of large language models (LLMs) in math, coding, and multi-hop reasoning tasks. However, RL fine-tuning requires abundant high-quality verifiable data,…

Prompt engineering is crucial for achieving reliable and effective outputs from large language models (LLMs), but its design requires specialized knowledge of prompting techniques and a deep understanding of target tasks. To address this…

Computation and Language · Computer Science 2025-10-22 Yohei Ikenoue , Hitomi Tashiro , Shigeru Kuroyanagi

Electronic health records (EHRs) store an extensive array of patient information, encompassing medical histories, diagnoses, treatments, and test outcomes. These records are crucial for enabling healthcare providers to make well-informed…

Computation and Language · Computer Science 2023-08-07 Yu-Neng Chuang , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Supervised training of an automated medical image analysis system often requires a large amount of expert annotations that are hard to collect. Moreover, the proportions of data available across different classes may be highly imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yuan Xue , Jiarong Ye , Rodney Long , Sameer Antani , Zhiyun Xue , Xiaolei Huang

Reinforcement learning (RL) has emerged as a powerful paradigm for improving large language models beyond supervised fine-tuning, yet sustaining performance gains at scale remains an open challenge, as data diversity and structure, rather…

Machine Learning · Computer Science 2026-03-26 Cansu Sancaktar , David Zhang , Gabriel Synnaeve , Taco Cohen

Large Language Models (LLMs) have demonstrated remarkable capabilities across diverse domains, but developing high-performing models for specialized applications often requires substantial human annotation -- a process that is…

Computation and Language · Computer Science 2025-07-30 Abhinav Arabelly , Jagrut Nemade , Robert D Nowak , Jifan Zhang
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