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We present an novel framework for efficiently and effectively extending the powerful continuous diffusion processes to discrete modeling. Previous approaches have suffered from the discrepancy between discrete data and continuous modeling.…

Machine Learning · Computer Science 2024-10-31 Yuxuan Gu , Xiaocheng Feng , Lei Huang , Yingsheng Wu , Zekun Zhou , Weihong Zhong , Kun Zhu , Bing Qin

While supervised stereo matching and monocular depth estimation have advanced significantly with learning-based algorithms, self-supervised methods using stereo images as supervision signals have received relatively less focus and require…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Zihua Liu , Yizhou Li , Songyan Zhang , Masatoshi Okutomi

Diffusion models have shown impressive results in generating high-quality conditional samples using guidance techniques such as Classifier-Free Guidance (CFG). However, existing methods often require additional training or neural function…

Machine Learning · Computer Science 2025-07-22 Kwanyoung Kim , Byeongsu Sim

Deep learning model effectiveness in classification tasks is often challenged by the quality and quantity of training data whenever they are affected by strong spurious correlations between specific attributes and target labels. This…

A common challenge in the natural sciences is to disentangle distinct, unknown sources from observations. Examples of this source separation task include deblending galaxies in a crowded field, distinguishing the activity of individual…

Machine Learning · Computer Science 2025-10-08 Sebastian Wagner-Carena , Aizhan Akhmetzhanova , Sydney Erickson

Generative diffusion models have achieved remarkable success in producing high-quality images. However, these models typically operate in continuous intensity spaces, diffusing independently across pixels and color channels. As a result,…

Graphics · Computer Science 2025-05-20 Javier E. Santos , Agnese Marcato , Roman Colman , Nicholas Lubbers , Yen Ting Lin

Generative graph models struggle to scale due to the need to predict the existence or type of edges between all node pairs. To address the resulting quadratic complexity, existing scalable models often impose restrictive assumptions such as…

Machine Learning · Computer Science 2024-05-24 Yiming Qin , Clement Vignac , Pascal Frossard

Source localization is a representative inverse inference task in information propagation, aiming to identify the source node or node set that triggers the propagation results based on the observed information. A primary challenge is…

Social and Information Networks · Computer Science 2026-05-06 Yansong Wang , Qisen Chai , Longlong Lin , Tao Jia

Modern technology for producing extremely bright and coherent X-ray laser pulses provides the possibility to acquire a large number of diffraction patterns from individual biological nanoparticles, including proteins, viruses, and DNA.…

Methodology · Statistics 2018-07-11 Stefan Engblom , Carl Nettelblad , Jing Liu

We train a neural network to predict distributional responses in gene expression following genetic perturbations. This is an essential task in early-stage drug discovery, where such responses can offer insights into gene function and inform…

While diffusion models have achieved great success in generating continuous signals such as images and audio, it remains elusive for diffusion models in learning discrete sequence data like natural languages. Although recent advances…

Computation and Language · Computer Science 2024-05-02 Jiasheng Ye , Zaixiang Zheng , Yu Bao , Lihua Qian , Mingxuan Wang

Adapting a pretrained diffusion model to new objectives at inference time remains an open problem in generative modeling. Existing steering methods suffer from inaccurate value estimation, especially at high noise levels, which biases…

Machine Learning · Computer Science 2025-06-27 Vineet Jain , Kusha Sareen , Mohammad Pedramfar , Siamak Ravanbakhsh

Diffusion models (DMs) embark a new era of generative modeling and offer more opportunities for efficient generating high-quality and realistic data samples. However, their widespread use has also brought forth new challenges in model…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Jingyao Xu , Yuetong Lu , Yandong Li , Siyang Lu , Dongdong Wang , Xiang Wei

Domain Generalization techniques aim to enhance model robustness by simulating novel data distributions during training, typically through various augmentation or stylization strategies. However, these methods frequently suffer from limited…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Mehrdad Noori , Milad Cheraghalikhani , Ali Bahri , Gustavo Adolfo Vargas Hakim , David Osowiechi , Moslem Yazdanpanah , Ismail Ben Ayed , Christian Desrosiers

Denoising diffusion models have become ubiquitous for generative modeling. The core idea is to transport the data distribution to a Gaussian by using a diffusion. Approximate samples from the data distribution are then obtained by…

Diffuse optical tomography (DOT) is a severely ill-posed nonlinear inverse problem that seeks to estimate optical parameters from boundary measurements. In the Bayesian framework, the ill-posedness is diminished by incorporating {\em a…

Numerical Analysis · Mathematics 2023-12-06 Anssi Manninen , Meghdoot Mozumder , Tanja Tarvainen , Andreas Hauptmann

Discrete diffusion models generate sequences by iteratively denoising samples corrupted by categorical noise, offering an appealing alternative to autoregressive decoding for structured and symbolic generation. However, standard training…

Machine Learning · Computer Science 2026-02-04 Huu Binh Ta , Michael Cardei , Alvaro Velasquez , Ferdinando Fioretto

Dual-target therapeutic strategies have become a compelling approach and attracted significant attention due to various benefits, such as their potential in overcoming drug resistance in cancer therapy. Considering the tremendous success…

Machine Learning · Computer Science 2024-11-27 Xiangxin Zhou , Jiaqi Guan , Yijia Zhang , Xingang Peng , Liang Wang , Jianzhu Ma

In diffusion models, samples are generated through an iterative refinement process, requiring hundreds of sequential model evaluations. Several recent methods have introduced approximations (fewer discretization steps or distillation) to…

Machine Learning · Computer Science 2024-12-12 Nikil Roashan Selvam , Amil Merchant , Stefano Ermon

Score-based generative models (SGMs) have recently emerged as a promising class of generative models. However, a fundamental limitation is that their sampling process is slow due to a need for many (e.g., 2000) iterations of sequential…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Hengyuan Ma , Xiatian Zhu , Jianfeng Feng , Li Zhang
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