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Magnetic resonance spectroscopy (MRS) is an important technique in biomedical research and it has the unique capability to give a non-invasive access to the biochemical content (metabolites) of scanned organs. In the literature, the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Nima Hatami , Michaël Sdika , Hélène Ratiney

Nuclear Magnetic Resonance (NMR) spectra are widely used in metabolomics to obtain profiles of metabolites dissolved in biofluids such as cell supernatants. Methods for estimating metabolite concentrations from these spectra are presently…

Methodology · Statistics 2012-05-16 William Astle , Maria De Iorio , Sylvia Richardson , David Stephens , Timothy Ebbels

Ultrahigh field (UHF) Magnetic Resonance Imaging (MRI) provides a higher signal-to-noise ratio and, thereby, higher spatial resolution. However, UHF MRI introduces challenges such as transmit radiofrequency (RF) field (B1+) inhomogeneities,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Zhengyi Lu , Hao Liang , Xiao Wang , Xinqiang Yan , Yuankai Huo

Objective Maps of B0 field inhomogeneities are often used to improve MRI image quality, even in a retrospective fashion. These field inhomogeneities depend on the exact head position within the static field but acquiring field maps (FM) at…

Medical Physics · Physics 2022-10-03 Jiazheng Zhou , Gisela E Hagberg , Ali Aghaeifar , Jonas Bause , Maxim Zaitsev , Klaus Scheffler

In a mixed generalized linear model, the goal is to learn multiple signals from unlabeled observations: each sample comes from exactly one signal, but it is not known which one. We consider the prototypical problem of estimating two…

Statistics Theory · Mathematics 2026-01-12 Yihan Zhang , Marco Mondelli , Ramji Venkataramanan

Many current neural networks for medical imaging generalise poorly to data unseen during training. Such behaviour can be caused by networks overfitting easy-to-learn, or statistically dominant, features while disregarding other potentially…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Joona Pohjonen , Carolin Stürenberg , Antti Rannikko , Tuomas Mirtti , Esa Pitkänen

Deep representation learning is a crucial procedure in multimedia analysis and attracts increasing attention. Most of the popular techniques rely on convolutional neural network and require a large amount of labeled data in the training…

Computer Vision and Pattern Recognition · Computer Science 2020-09-14 Jinghua Wang , Adrian Hilton , Jianmin Jiang

Spectral methods have emerged as a simple yet surprisingly effective approach for extracting information from massive, noisy and incomplete data. In a nutshell, spectral methods refer to a collection of algorithms built upon the eigenvalues…

Machine Learning · Statistics 2021-10-26 Yuxin Chen , Yuejie Chi , Jianqing Fan , Cong Ma

In this paper, we develop a novel framework to optimally design spectral estimators for phase retrieval given measurements realized from an arbitrary model. We begin by deconstructing spectral methods, and identify the fundamental…

Signal Processing · Electrical Eng. & Systems 2020-12-14 Bariscan Yonel , Birsen Yazici

Scientific machine learning increasingly uses spectral methods to understand physical systems. Current spectral learning approaches provide only point estimates without uncertainty quantification, limiting their use in safety-critical…

Machine Learning · Computer Science 2025-09-17 Mohammad Nooraiepour

Spectral methods which represent data points by eigenvectors of kernel matrices or graph Laplacian matrices have been a primary tool in unsupervised data analysis. In many application scenarios, parametrizing the spectral embedding by a…

Machine Learning · Statistics 2022-06-15 Ziyu Chen , Yingzhou Li , Xiuyuan Cheng

Classification models are expected to perform equally well for different classes, yet in practice, there are often large gaps in their performance. This issue of class bias is widely studied in cases of datasets with sample imbalance, but…

Machine Learning · Computer Science 2024-06-04 Chiraag Kaushik , Ran Liu , Chi-Heng Lin , Amrit Khera , Matthew Y Jin , Wenrui Ma , Vidya Muthukumar , Eva L Dyer

Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrumentation and resulting data, sophisticated…

Deep learning has demonstrated remarkable achievements in medical image segmentation. However, prevailing deep learning models struggle with poor generalization due to (i) intra-class variations, where the same class appears differently in…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Vandan Gorade , Sparsh Mittal , Debesh Jha , Rekha Singhal , Ulas Bagci

Mass spectrometry-based metabolomic analysis depends upon the identification of spectral peaks by their mass and retention time. Statistical analysis that follows the identification currently relies on one main peak of each compound.…

Quantitative Methods · Quantitative Biology 2014-03-20 Tommi Suvitaival , Simon Rogers , Samuel Kaski

Background: Magnetic resonance spectroscopy (MRS) enables non-invasive detection and measurement of biochemicals and metabolites. However, MRS has low signal-to-noise ratio (SNR) when concentrations of metabolites are in the range of the…

Medical Physics · Physics 2023-03-30 Jing Wang , Bing Ji , Yang Lei , Tian Liu , Hui Mao , Xiaofeng Yang

Multimodal manifold modeling methods extend the spectral geometry-aware data analysis to learning from several related and complementary modalities. Most of these methods work based on two major assumptions: 1) there are the same number of…

Machine Learning · Computer Science 2021-05-13 Maysam Behmanesh , Peyman Adibi , Jocelyn Chanussot , Sayyed Mohammad Saeed Ehsani

In this study, a spectral graph-theoretic grouping strategy for weakly supervised classification is introduced, where a limited number of labelled samples and a larger set of unlabelled samples are used to construct a larger annotated…

Machine Learning · Computer Science 2015-08-04 Tameem Adel , Alexander Wong , Daniel Stashuk

In recent years, hyperspectral imaging, also known as imaging spectroscopy, has been paid an increasing interest in geoscience and remote sensing community. Hyperspectral imagery is characterized by very rich spectral information, which…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Danfeng Hong , Jing Yao , Xin Wu , Jocelyn Chanussot , Xiao Xiang Zhu

Forecasting multiscale chaotic dynamical systems, such as turbulent flows, with deep learning remains a formidable challenge due to the spectral bias of neural networks, which hinders the accurate representation of fine-scale structures in…

Machine Learning · Computer Science 2026-03-31 Dibyajyoti Chakraborty , Arvind T. Mohan , Romit Maulik
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