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Dual-energy computed tomography (DECT) is of great significance for clinical practice due to its huge potential to provide material-specific information. However, DECT scanners are usually more expensive than standard single-energy CT…
Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with existing high-end DECT leveraging advanced X-ray…
Brain tumor segmentation is important for diagnosis of the tumor, and current deep-learning methods rely on a large set of annotated images for training, with high annotation costs. Unsupervised segmentation is promising to avoid human…
99m-Tc Ethyl-Cysteinate-Dimer SPECT and MR imaging play a significant role in diagnosing anosmia. In this study, two-tissue class and three-tissue class attenuation maps (2C-MR and 3CMR) obtained from MR images were compared with CT-based…
Circulating tumor cells (CTCs) are crucial biomarkers in liquid biopsy, offering a noninvasive tool for cancer patient management. However, their identification remains particularly challenging due to their limited number and heterogeneity.…
Due to the black-box nature of deep learning models, there is a recent development of solutions for visual explanations of CNNs. Given the high cost of user studies, metrics are necessary to compare and evaluate these different methods. In…
Deep learning has demonstrated remarkable achievements in medical image segmentation. However, prevailing deep learning models struggle with poor generalization due to (i) intra-class variations, where the same class appears differently in…
Recently, deep learning (DL) found its way to interventional X-ray skin dose estimation. While its performance was found to be acceptable, even more accurate results could be achieved if more data sets were available for training. One…
Medical Image Segmentation is a useful application for medical image analysis including detecting diseases and abnormalities in imaging modalities such as MRI, CT etc. Deep learning has proven to be promising for this task but usually has a…
Background: In medical imaging, images are usually treated as deterministic, while their uncertainties are largely underexplored. Purpose: This work aims at using deep learning to efficiently estimate posterior distributions of imaging…
With the development of deep learning, medical image processing has been widely used to assist clinical research. This paper focuses on the denoising problem of low-dose computed tomography using deep learning. Although low-dose computed…
Versatile medical image segmentation (VMIS) targets the segmentation of multiple classes, while obtaining full annotations for all classes is often impractical due to the time and labor required. Leveraging partially labeled datasets (PLDs)…
To investigate whether and to what extent central serous chorioretinopathy (CSC) depicted on color fundus photographs can be assessed using deep learning technology. We collected a total of 2,504 fundus images acquired on different…
In PET/CT imaging, CT is used for PET attenuation correction (AC). Mismatch between CT and PET due to patient body motion results in AC artifacts. In addition, artifact caused by metal, beam-hardening and count-starving in CT itself also…
Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…
Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…
Supervised deep learning-based methods yield accurate results for medical image segmentation. However, they require large labeled datasets for this, and obtaining them is a laborious task that requires clinical expertise.…
Purpose: The expansion of radiopharmaceutical therapy (RPT) development demands scalable preclinical dosimetry methods. While PET and SPECT remain the gold standards, their low throughput and high cost limit large-cohort studies. Cherenkov…
Single-photon emission computed tomography (SPECT) provides a mechanism to estimate regional isotope uptake in lesions and at-risk organs after administration of {\alpha}-particle-emitting radiopharmaceutical therapies ({\alpha}-RPTs).…
Dual-energy computed tomography (DECT) enables material-specific imaging through acquisitions at two different X-ray energy spectra. Material decomposition from DECT data is an ill-posed inverse problem that is highly sensitive to noise…