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In the field of biomedical image analysis, the quest for architectures capable of effectively capturing long-range dependencies is paramount, especially when dealing with 3D image segmentation, classification, and landmark detection.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Haifan Gong , Luoyao Kang , Yitao Wang , Xiang Wan , Haofeng Li

The advent of Transformer and Mamba-based architectures has significantly advanced 3D medical image segmentation by enabling global contextual modeling, a capability traditionally limited in Convolutional Neural Networks (CNNs). However,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Duy D. Nguyen , Phat T. Tran-Truong

State-space models (SSMs), particularly Mamba, have become powerful architectures for sequence modeling, yet their internal dynamics remain poorly understood compared to attention-based models. We introduce and validate the Influence Score,…

Machine Learning · Computer Science 2025-11-25 Mohamed Mabrok , Yalda Zafari

Transformers have become one of the foundational architectures in point cloud analysis tasks due to their excellent global modeling ability. However, the attention mechanism has quadratic complexity, making the design of a linear complexity…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Dingkang Liang , Xin Zhou , Wei Xu , Xingkui Zhu , Zhikang Zou , Xiaoqing Ye , Xiao Tan , Xiang Bai

Medicine is inherently a multimodal discipline. Medical images can reflect the pathological changes of cancer and tumors, while the expression of specific genes can influence their morphological characteristics. However, most deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Jiaying Zhou , Mingzhou Jiang , Junde Wu , Jiayuan Zhu , Ziyue Wang , Yueming Jin

Accurate medical image segmentation requires effective modeling of both global anatomical structures and fine-grained boundary details. Recent state space models (e.g., Vision Mamba) offer efficient long-range dependency modeling. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Fuhao Zhang , Lei Liu , Jialin Zhang , Ya-Nan Zhang , Nan Mu

State Space Models (SSMs) have emerged as powerful alternatives to attention-based Transformers, with Mamba demonstrating impressive efficiency and scalability. As these models grow increasingly larger, the need for Parameter-Efficient…

Machine Learning · Computer Science 2026-03-03 Donghyun Lee , Yuhang Li , Ruokai Yin , Shiting Xiao , Priyadarshini Panda

Over the past few years, technological advances have allowed for measurement of omics data at the cell level, creating a new type of data generally referred to as single-cell (sc) omics. On the other hand, the so-called spatial omics are a…

CrackMamba, a Mamba-based model, is designed for efficient and accurate crack segmentation for monitoring the structural health of infrastructure. Traditional Convolutional Neural Network (CNN) models struggle with limited receptive fields,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Xin Zuo , Yu Sheng , Jifeng Shen , Yongwei Shan

Over the past decade, the revolution in single-cell sequencing has enabled the simultaneous molecular profiling of various modalities across thousands of individual cells, allowing scientists to investigate the diverse functions of complex…

Computation and Language · Computer Science 2024-12-05 Junhao Liu , Siwei Xu , Lei Zhang , Jing Zhang

Scribble annotations significantly reduce the cost and labor required for dense labeling in large medical datasets with complex anatomical structures. However, current scribble-supervised learning methods are limited in their ability to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Luyi Qiu , Tristan Till , Xiaobao Guo , Adams Wai-Kin Kong

The diffusion model has long been plagued by scalability and quadratic complexity issues, especially within transformer-based structures. In this study, we aim to leverage the long sequence modeling capability of a State-Space Model called…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Vincent Tao Hu , Stefan Andreas Baumann , Ming Gui , Olga Grebenkova , Pingchuan Ma , Johannes Schusterbauer , Björn Ommer

State Space Models (SSMs), especially Mamba, have shown great promise in medical image segmentation due to their ability to model long-range dependencies with linear computational complexity. However, accurate medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Chaowei Chen , Li Yu , Shiquan Min , Shunfang Wang

The field of neuromorphic computing has gained significant attention in recent years, aiming to bridge the gap between the efficiency of biological neural networks and the performance of artificial intelligence systems. This paper…

Neural and Evolutionary Computing · Computer Science 2024-08-23 Jiahao Qin , Feng Liu

Deep learning-based single-channel speaker separation has improved significantly in recent years largely due to the introduction of the transformer-based attention mechanism. However, these improvements come at the expense of intense…

Advances in high-throughput technologies have originated an ever-increasing availability of omics datasets. The integration of multiple heterogeneous data sources is currently an issue for biology and bioinformatics. Multiple kernel…

Machine Learning · Statistics 2024-12-04 Mitja Briscik , Gabriele Tazza , Marie-Agnes Dillies , László Vidács , Sébastien Dejean

Multiple Instance Learning (MIL) has emerged as a dominant paradigm to extract discriminative feature representations within Whole Slide Images (WSIs) in computational pathology. Despite driving notable progress, existing MIL approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Shu Yang , Yihui Wang , Hao Chen

We present scPilot, the first systematic framework to practice omics-native reasoning: a large language model (LLM) converses in natural language while directly inspecting single-cell RNA-seq data and on-demand bioinformatics tools. scPilot…

Artificial Intelligence · Computer Science 2026-02-13 Yiming Gao , Zhen Wang , Jefferson Chen , Mark Antkowiak , Mengzhou Hu , JungHo Kong , Dexter Pratt , Jieyuan Liu , Enze Ma , Zhiting Hu , Eric P. Xing

The Audio-Visual Question Answering (AVQA) task holds significant potential for applications. Compared to traditional unimodal approaches, the multi-modal input of AVQA makes feature extraction and fusion processes more challenging.…

Artificial Intelligence · Computer Science 2024-07-17 Zhe Yang , Wenrui Li , Guanghui Cheng

Integration of multi-omics data provides opportunities for revealing biological mechanisms related to certain phenotypes. We propose a novel method of multi-omics integration called supervised deep generalized canonical correlation analysis…

Quantitative Methods · Quantitative Biology 2022-04-21 Jeongyoung Hwang , Sehwan Moon , Hyunju Lee