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Most of the calcium in the body is stored in bone. The rest is stored elsewhere, and calcium signalling is one of the most important mechanisms of information propagation in the body. Yet, many questions remain open. In this work, we…

Dynamical Systems · Mathematics 2017-03-03 Katerina Kaouri , Philip K. Maini , S. Jonathan Chapman

A new method is proposed to numerically extract the diffusivity of a (typically nonlinear) diffusion equation from underlying stochastic particle systems. The proposed strategy requires the system to be in local equilibrium and have…

Statistical Mechanics · Physics 2018-05-09 Peter Embacher , Nicolas Dirr , Johannes Zimmer , Celia Reina

Kinetic plasma processes, such as magnetic reconnection, collisionless shocks, and turbulence, are fundamental to the dynamics of astrophysical and laboratory plasmas. Simulating these processes often requires particle-in-cell (PIC)…

Plasma Physics · Physics 2025-06-11 S. R. Totorica , K. V. Lezhnin , W. Fox

Modeling physical systems in a generative manner offers several advantages, including the ability to handle partial observations, generate diverse solutions, and address both forward and inverse problems. Recently, diffusion models have…

Machine Learning · Computer Science 2025-05-29 Yi Zhang , Difan Zou

Reaction diffusion systems are often used to study pattern formation in biological systems. However, most methods for understanding their behavior are challenging and can rarely be applied to complex systems common in biological…

Analysis of PDEs · Mathematics 2013-05-24 William R. Holmes

A partial differential equation (PDE) was developed to describe time-dependent ligand-receptor interactions for applications in biosensing using field effect transistors (FET). The model describes biochemical interactions at the sensor…

Analysis of PDEs · Mathematics 2017-10-20 Ryan M. Evans , Arvind Balijepalli , Anthony J. Kearsley

In this paper, we introduce and study one-dimensional models for the behavior of pedestrians in a narrow street or corridor. We begin at the microscopic level by formulating a stochastic cellular automata model with explicit rules for…

Probability · Mathematics 2012-09-27 Alina Chertock , Alexander Kurganov , Anthony Polizzi , Ilya Timofeyev

1. Understanding the mechanisms underlying biological systems, and ultimately, predicting their behaviours in a changing environment requires overcoming the gap between mathematical models and experimental or observational data.…

Quantitative Methods · Quantitative Biology 2017-04-19 Philipp H Boersch-Supan , Sadie J Ryan , Leah R Johnson

This paper concerns the modeling and numerical simulation of the process of speciation. In particular, given conditions for which one or more speciation events within an ecosystem occur, our aim is to develop the necessary modeling and…

Populations and Evolution · Quantitative Biology 2021-10-08 Mats K. Brun , Elyes Ahmed , Jan Martin Nordbotten , Nils Christian Stenseth

Usually, the systems of partial differential equations (PDEs) are discovered from observational data in the single vector equation form. However, this approach restricts the application to the real cases, where, for example, the form of the…

Neural and Evolutionary Computing · Computer Science 2021-08-13 Mikhail Maslyaev , Alexander Hvatov

Most of the functions performed by astrocytes in brain information processing are related to calcium waves. Experimental studies involving calcium waves present discrepant results, leading to gaps in the full understanding of the functions…

Biological Physics · Physics 2021-07-09 Thais Appelt Peres Bartiê , Leonel Teixeira Pinto

Sparse system identification of nonlinear dynamic systems is still challenging, especially for stiff and high-order differential equations for noisy measurement data. The use of highly correlated functions makes distinguishing between true…

Computational Physics · Physics 2025-12-19 Ashish Pal , Sutanu Bhowmick , Satish Nagarajaiah

Sea ice profoundly influences the polar environment and the global climate. Traditionally, Sea ice has been modeled as a continuum under Eulerian coordinates to describe its large-scale features, using, for instance, viscous-plastic…

Numerical Analysis · Mathematics 2023-08-16 Quanling Deng , Samuel N. Stechmann , Nan Chen

Digital communication systems inherently operate through physical media governed by partial differential equations (PDEs). In this paper, we introduce a physics-aware decoding framework that integrates gradient descent-based error…

Information Theory · Computer Science 2025-01-28 Tadashi Wadayama , Koji Igarashi , Takumi Takahashi

We propose a novel method, Phase-IDENT, for identifying partial differential equations (PDEs) from noisy observations of dynamical systems that exhibit phase transitions. Such phenomena are prevalent in fluid dynamics and materials science,…

Numerical Analysis · Mathematics 2026-01-21 Edward L. Yang , Roy Y. He

Complex spatiotemporal dynamics of physicochemical processes are often modeled at a microscopic level (through e.g. atomistic, agent-based or lattice models) based on first principles. Some of these processes can also be successfully…

We consider the problem of solving partial differential equations (PDEs) in domains with complex microparticle geometry that is impractical, or intractable, to model explicitly. Drawing inspiration from volume rendering, we propose tackling…

Graphics · Computer Science 2025-06-11 Bailey Miller , Rohan Sawhney , Keenan Crane , Ioannis Gkioulekas

In this article we propose and investigate a hierarchy of mathematical models based on partial differential equations (PDE) and ordinary differential equations (ODE) for the simulation of the biophysical phenomena occurring in the…

Numerical Analysis · Mathematics 2016-01-20 Emanuela Abbate , Matteo Porro , Thierry Nieus , Riccardo Sacco

We consider a model for the dynamics of active cells interacting with their quiescent counterparts under the influence of acidity characterized by proton concentration. The active cells perform nonlinear diffusion and infer proliferation or…

Analysis of PDEs · Mathematics 2025-11-04 Maria Eckardt , Christina Surulescu

Autoregressive next-step prediction models have become the de-facto standard for building data-driven neural solvers to forecast time-dependent partial differential equations (PDEs). Denoise training that is closely related to diffusion…

Machine Learning · Computer Science 2025-03-31 Zijie Li , Anthony Zhou , Amir Barati Farimani
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