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Coded-illumination can enable quantitative phase microscopy of transparent samples with minimal hardware requirements. Intensity images are captured with different source patterns and a non-linear phase retrieval optimization reconstructs…

Signal Processing · Electrical Eng. & Systems 2019-02-07 Michael R. Kellman , Emrah Bostan , Nicole Repina , Laura Waller

Photonic integrated circuits offer a compact and stable platform for generating, manipulating, and detecting light. They are instrumental for classical and quantum applications. Imperfections stemming from fabrication constraints,…

Integrated photonic neural networks (PNNs) are at the forefront of AI computing, leveraging on light's unique properties, such as large bandwidth, low latency, and potentially low power consumption. Nevertheless, the integrated optical…

Nanophotonics finds ever broadening applications requiring complex component designs with a large number of parameters to be simultaneously optimized. Recent methodologies employing optimization algorithms commonly focus on a single design…

The incorporation of high-performance optoelectronic devices into photonic neuromorphic processors can substantially accelerate computationally intensive operations in machine learning (ML) algorithms. However, the conventional device…

Emerging Technologies · Computer Science 2022-03-14 Yingheng Tang , Princess Tara Zamani , Ruiyang Chen , Jianzhu Ma , Minghao Qi , Cunxi Yu , Weilu Gao

The recent explosive compute growth, mainly fueled by the boost of AI and DNNs, is currently instigating the demand for a novel computing paradigm that can overcome the insurmountable barriers imposed by conventional electronic computing…

This paper introduces a new method of data-driven microscope design for virtual fluorescence microscopy. Our results show that by including a model of illumination within the first layers of a deep convolutional neural network, it is…

Image and Video Processing · Electrical Eng. & Systems 2020-04-23 Colin L. Cooke , Fanjie Kong , Amey Chaware , Kevin C. Zhou , Kanghyun Kim , Rong Xu , D. Michael Ando , Samuel J. Yang , Pavan Chandra Konda , Roarke Horstmeyer

Next-generation integrated nanophotonic device designs leverage advanced optimization techniques such as inverse design and topology optimization which achieve high performance and extreme miniaturization by optimizing a massively complex…

Machine Learning · Computer Science 2023-03-23 Dusan Gostimirovic , Yuri Grinberg , Dan-Xia Xu , Odile Liboiron-Ladouceur

Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field-of-view, and phototoxicity. To overcome these limitations,…

Quantitative Methods · Quantitative Biology 2024-04-01 Leonor Morgado , Estibaliz Gómez-de-Mariscal , Hannah S. Heil , Ricardo Henriques

Real-world environment-derived point clouds invariably exhibit noise across varying modalities and intensities. Hence, point cloud denoising (PCD) is essential as a preprocessing step to improve downstream task performance. Deep learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Chengwei Zhang , Xueyi Zhang , Mingrui Lao , Tao Jiang , Xinhao Xu , Wenjie Li , Fubo Zhang , Longyong Chen

The recent surge in the adoption of machine learning techniques for materials design, discovery, and characterization has resulted in an increased interest and application of Image Driven Machine Learning (IDML) approaches. In this work, we…

Materials Science · Physics 2021-05-21 Arun Baskaran , Elizabeth J. Kautz , Aritra Chowdhary , Wufei Ma , Bulent Yener , Daniel J. Lewis

Photonics is becoming a cornerstone technology for high-performance AI systems and scientific computing, offering unparalleled speed, parallelism, and energy efficiency. Despite this promise, the design and deployment of electronic-photonic…

Optics · Physics 2026-01-05 Hongjian Zhou , Ziang Yin , Jiaqi Gu

Over the past decade alternative technologies have gained momentum as conventional digital electronics continue to approach their limitations, due to the end of Moore's Law and Dennard Scaling. At the same time, we are facing new…

Emerging Technologies · Computer Science 2020-06-16 Armin Mehrabian , Volker J. Sorger , Tarek El-Ghazawi

With the emergence of new photonic and plasmonic materials with optimized properties as well as advanced nanofabrication techniques, nanophotonic devices are now capable of providing solutions to global challenges in energy conversion,…

X-ray photon-counting detectors (PCDs) are drawing an increasing attention in recent years due to their low noise and energy discrimination capabilities. The energy/spectral dimension associated with PCDs potentially brings great benefits…

Medical Physics · Physics 2020-07-08 Mengzhou Li , David S. Rundle , Ge Wang

Materials synthesis platforms that are designed for autonomous experimentation are capable of collecting multimodal diagnostic data that can be utilized for feedback to optimize material properties. Pulsed laser deposition (PLD) is emerging…

Materials Science · Physics 2024-11-01 Sumner B. Harris , Christopher M. Rouleau , Kai Xiao , Rama K. Vasudevan

Neural networks provide a powerful tool for applications from classification and regression to general purpose alternative computing. Photonics have the potential to provide enormous speed benefits over electronic and software networks,…

Signal Processing · Electrical Eng. & Systems 2018-10-18 Ethan Gordon

We present our new experimental and theoretical framework which combines a broadband superluminescent diode (SLED/SLD) with fast learning algorithms to provide speed and accuracy improvements for the optimization of 1D optical dipole…

This paper shows how data-driven machine learning approaches can improve growth control, reproducibility, and physical insight in the pulsed laser deposition (PLD) growth of correlated oxides. Despite well-known relationships between growth…

Probabilistic computing excels in approximating combinatorial problems and modelling uncertainty. However, using conventional deterministic hardware for probabilistic models is challenging: (pseudo) random number generation introduces…

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