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Stimulated Raman scattering (SRS) represents a powerful tool for accessing the vibrational properties of molecular compounds or solid state systems. From a spectroscopic perspective, SRS is able to capture Raman spectra free from incoherent…

We show that combining vibrational spectroscopy with signal processing can result in a scheme for ultrasensitive detection of molecules. We consider the vibrational spectrum as a signal on the energy axis and apply a matched filter on that…

Computational Physics · Physics 2018-12-10 Tay Yong Boon , Ian Tay Rongde , Loy Liang Yi , Aw Ke Fun , Ong Zhi Li , Sergei Manzhos

Vibrational spectroscopy is a key technique to elucidate microscopic structure and dynamics. Without the aid of theoretical approaches, it is however, often difficult to understand such spectra at a microscopic level. Ab initio molecular…

Chemical Physics · Physics 2023-03-14 Philipp Schienbein

One of the most widely used chiroptical spectroscopic methods for studying chiral molecules is Raman optical activity; however, the chiral Raman optical activity signal is extremely weak. Here, we theoretically examine enhanced chiral…

Quantum Physics · Physics 2019-05-03 Tuguldur Kh. Begzjav , Zhedong Zhang , Marlan O. Scully , Girish S. Agarwal

Stimulated Raman spectroscopy has become a powerful tool to study the spatiodynamics of molecular bonds with high sensitivity, resolution and speed. However, sensitivity and speed of state-of-the-art stimulated Raman spectroscopy are…

Raman spectroscopy uses light scattering to extract information on low-energy excitations of solids. The Raman process is described by diagrams which are fourth order in the light-matter interaction, and in particular the resonant…

Strongly Correlated Electrons · Physics 2024-01-30 Philipp Werner , Martin Eckstein , Naoto Tsuji

Raman spectroscopy stands as a cornerstone technique for probing collective excitations and emergent quantum phases in solids. While polarization-resolved Raman scattering has been widely used to extract symmetry information of eigenmodes,…

Materials Science · Physics 2026-02-24 Di Cheng , Junxiang Li , Shizhuo Luo , Zehao Chen , Xinwei Li

Raman spectroscopy enables non-destructive, label-free imaging with unprecedented molecular contrast but is limited by slow data acquisition, largely preventing high-throughput imaging applications. Here, we present a comprehensive…

Image and Video Processing · Electrical Eng. & Systems 2021-12-02 Conor C. Horgan , Magnus Jensen , Anika Nagelkerke , Jean-Phillipe St-Pierre , Tom Vercauteren , Molly M. Stevens , Mads S. Bergholt

Machine learning (ML) has emerged as a pervasive tool in science, engineering, and beyond. Its success has also led to several synergies with molecular dynamics (MD) simulations, which we use to identify and characterize the major…

Biomolecules · Quantitative Biology 2022-05-09 Christopher Kolloff , Simon Olsson

The extensive use of pesticides and synthetic dyes poses critical threats to food safety, human health, and environmental sustainability, necessitating rapid and reliable detection methods. Raman spectroscopy offers molecularly specific…

Materials Science · Physics 2025-11-18 Quach Thi Thai Binh , Thuan Phuoc , Xuan Hai , Thang Bach Phan , Vu Thi Hanh Thu , Nguyen Tuan Hung

We present a practical method to compute the vibrational resonant Raman spectra in solids with delocalized excitations. We apply this approach to the study of tetrahedrous amorphous carbon. We determine the vibrational eigenmodes and…

Materials Science · Physics 2009-11-07 Mickael Profeta , Francesco Mauri

Magnetic resonance spectroscopic imaging is a widely available imaging modality that can non-invasively provide a metabolic profile of the tissue of interest, yet is challenging to integrate clinically. One major reason is the expensive,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 John LaMaster , Dhritiman Das , Florian Kofler , Jason Crane , Yan Li , Tobias Lasser , Bjoern H Menze

Machine learning encompasses a set of tools and algorithms which are now becoming popular in almost all scientific and technological fields. This is true for molecular dynamics as well, where machine learning offers promises of extracting…

Random matrix theory (RMT) provides a framework to study the spectral fluctuations in physical systems. RMT is capable of making predictions for the fluctuations only after the removal of the secular properties of the spectrum. Spectral…

Statistical Mechanics · Physics 2018-03-02 Sherif M. Abuelenin

Machine learning methods have revolutionized the discovery process of new molecules and materials. However, the intensive training process of neural networks for molecules with ever-increasing complexity has resulted in exponential growth…

Emerging Technologies · Computer Science 2022-12-27 Hui Zhang , Jonathan Wei Zhong Lau , Lingxiao Wan , Liang Shi , Hong Cai , Xianshu Luo , Patrick Lo , Chee-Kong Lee , Leong-Chuan Kwek , Ai Qun Liu

Particle-based modeling of materials at atomic scale plays an important role in the development of new materials and understanding of their properties. The accuracy of particle simulations is determined by interatomic potentials, which…

Optical communication systems are always evolving to support the need for ever-increasing transmission rates. This demand is supported by the growth in complexity of communication systems which are moving towards ultra-wideband transmission…

Molecular representation is a critical element in our understanding of the physical world and the foundation for modern molecular machine learning. Previous molecular machine learning models have employed strings, fingerprints, global…

Machine Learning · Computer Science 2025-05-28 Daniil A. Boiko , Thiago Reschützegger , Benjamin Sanchez-Lengeling , Samuel M. Blau , Gabe Gomes

Raman spectroscopy is a powerful tool for material characterization. However, careful preprocessing is required for the identification and handling of noise, baseline drift, and random spikes. This paper presents a comprehensive approach to…

The use of machine learning (ML) algorithms in molecular simulations has become commonplace in recent years. There now exists, for instance, a multitude of ML force field algorithms that have enabled simulations approaching ab initio level…

Chemical Physics · Physics 2025-04-17 Jakub K. Sowa , Peter J. Rossky