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This review paper provides an integrated perspective of Explainable Artificial Intelligence techniques applied to Brain-Computer Interfaces. BCIs use predictive models to interpret brain signals for various high-stake applications. However,…

Human-Computer Interaction · Computer Science 2023-12-21 Param Rajpura , Hubert Cecotti , Yogesh Kumar Meena

Proteins are complex biomolecules that play a central role in various biological processes, making them critical targets for breakthroughs in molecular biology, medical research, and drug discovery. Deciphering their intricate, hierarchical…

Machine Learning · Computer Science 2025-05-09 Viet Thanh Duy Nguyen , Truong-Son Hy

Given the complexity and lack of transparency in deep neural networks (DNNs), extensive efforts have been made to make these systems more interpretable or explain their behaviors in accessible terms. Unlike most reviews, which focus on…

Artificial Intelligence · Computer Science 2024-01-17 Haoyi Xiong , Xuhong Li , Xiaofei Zhang , Jiamin Chen , Xinhao Sun , Yuchen Li , Zeyi Sun , Mengnan Du

Explainable Artificial Intelligence (XAI) has re-emerged in response to the development of modern AI and ML systems. These systems are complex and sometimes biased, but they nevertheless make decisions that impact our lives. XAI systems are…

Artificial Intelligence · Computer Science 2021-02-10 Shane T. Mueller , Elizabeth S. Veinott , Robert R. Hoffman , Gary Klein , Lamia Alam , Tauseef Mamun , William J. Clancey

The growing availability of data and computing power fuels the development of predictive models. In order to ensure the safe and effective functioning of such models, we need methods for exploration, debugging, and validation. New methods…

Machine Learning · Computer Science 2021-03-30 Szymon Maksymiuk , Alicja Gosiewska , Przemyslaw Biecek

As systems based on opaque Artificial Intelligence (AI) continue to flourish in diverse real-world applications, understanding these black box models has become paramount. In response, Explainable AI (XAI) has emerged as a field of research…

Last years have been characterized by an upsurge of opaque automatic decision support systems, such as Deep Neural Networks (DNNs). Although they have great generalization and prediction skills, their functioning does not allow obtaining…

Deep learning is becoming increasingly adopted in business and industry due to its ability to transform large quantities of data into high-performing models. These models, however, are generally regarded as black boxes, which, in spite of…

Machine Learning · Computer Science 2023-02-21 Stefan Druc , Peter Wooldridge , Adarsh Krishnamurthy , Soumik Sarkar , Aditya Balu

We propose ProtLLM, a versatile cross-modal large language model (LLM) for both protein-centric and protein-language tasks. ProtLLM features a unique dynamic protein mounting mechanism, enabling it to handle complex inputs where the natural…

Biomolecules · Quantitative Biology 2024-03-14 Le Zhuo , Zewen Chi , Minghao Xu , Heyan Huang , Heqi Zheng , Conghui He , Xian-Ling Mao , Wentao Zhang

Recommender systems are widely used in online services, with embedding-based models being particularly popular due to their expressiveness in representing complex signals. However, these models often function as a black box, making them…

Information Retrieval · Computer Science 2024-06-25 Yuxuan Lei , Jianxun Lian , Jing Yao , Xu Huang , Defu Lian , Xing Xie

Protein language models (pLMs), pre-trained via causal language modeling on protein sequences, have been a promising tool for protein sequence design. In real-world protein engineering, there are many cases where the amino acids in the…

Machine Learning · Computer Science 2023-03-30 Youhan Lee , Hasun Yu

Deployed artificial intelligence (AI) often impacts humans, and there is no one-size-fits-all metric to evaluate these tools. Human-centered evaluation of AI-based systems combines quantitative and qualitative analysis and human input. It…

Human-Computer Interaction · Computer Science 2023-03-14 Teresa Datta , John P. Dickerson

Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

Machine Learning · Computer Science 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

Language is essentially a complex, intricate system of human expressions governed by grammatical rules. It poses a significant challenge to develop capable AI algorithms for comprehending and grasping a language. As a major approach,…

The diffusion of artificial intelligence (AI) applications in organizations and society has fueled research on explaining AI decisions. The explainable AI (xAI) field is rapidly expanding with numerous ways of extracting information and…

Human-Computer Interaction · Computer Science 2021-01-27 Julie Gerlings , Arisa Shollo , Ioanna Constantiou

In the last years, XAI research has mainly been concerned with developing new technical approaches to explain deep learning models. Just recent research has started to acknowledge the need to tailor explanations to different contexts and…

Artificial Intelligence · Computer Science 2021-10-11 Bettina Finzel , David E. Tafler , Stephan Scheele , Ute Schmid

The growing interest in eXplainable Artificial Intelligence (XAI) has stimulated research on models with built-in interpretability, among which part-prototype models are particularly prominent. Part-Prototype Models (PPMs) classify inputs…

Machine Learning · Computer Science 2026-03-20 Khawla Elhadri , Tomasz Michalski , Adam Wróbel , Jörg Schlötterer , Bartosz Zieliński , Christin Seifert

In the last years, Artificial Intelligence (AI) has achieved a notable momentum that may deliver the best of expectations over many application sectors across the field. For this to occur, the entire community stands in front of the barrier…

Explainable Artificial Intelligence (XAI) techniques are used to provide transparency to complex, opaque predictive models. However, these techniques are often designed for image and text data, and it is unclear how fit-for-purpose they are…

Computers and Society · Computer Science 2024-10-18 Mythreyi Velmurugan , Chun Ouyang , Yue Xu , Renuka Sindhgatta , Bemali Wickramanayake , Catarina Moreira