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Knowledge of what spatial elements of medical images deep learning methods use as evidence is important for model interpretability, trustiness, and validation. There is a lack of such techniques for models in regression tasks. We propose a…

Image and Video Processing · Electrical Eng. & Systems 2020-07-27 Ricardo Bigolin Lanfredi , Joyce D. Schroeder , Clement Vachet , Tolga Tasdizen

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Despite recent progress, medical foundation models still struggle to unify visual understanding and generation, as these tasks have inherently conflicting goals: semantic abstraction versus pixel-level reconstruction. Existing approaches,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Ruiheng Zhang , Jingfeng Yao , Huangxuan Zhao , Hao Yan , Xiao He , Lei Chen , Zhou Wei , Yong Luo , Zengmao Wang , Lefei Zhang , Dacheng Tao , Bo Du

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Recent works show that Generative Adversarial Networks (GANs) can be successfully applied to chest X-ray data augmentation for lung disease recognition. However, the implausible and distorted pathology features generated from the less than…

Image and Video Processing · Electrical Eng. & Systems 2020-01-23 Yunyan Xing , Zongyuan Ge , Rui Zeng , Dwarikanath Mahapatra , Jarrel Seah , Meng Law , Tom Drummond

Ensuring the quality and integrity of medical images is crucial for maintaining diagnostic accuracy in deep learning-based Computer-Aided Diagnosis and Computer-Aided Detection (CAD) systems. Covariate shifts are subtle variations in the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Francisco Caetano , Christiaan Viviers , Lena Filatova , Peter H. N. de With , Fons van der Sommen

Blood vessel networks, represented as 3D graphs, help predict disease biomarkers, simulate blood flow, and aid in synthetic image generation, relevant in both clinical and pre-clinical settings. However, generating realistic vessel graphs…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Chinmay Prabhakar , Suprosanna Shit , Fabio Musio , Kaiyuan Yang , Tamaz Amiranashvili , Johannes C. Paetzold , Hongwei Bran Li , Bjoern Menze

Digital pathology has advanced significantly over the last decade, with Whole Slide Images (WSIs) encompassing vast amounts of data essential for accurate disease diagnosis. High-resolution WSIs are essential for precise diagnosis but…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Xuan Xu , Saarthak Kapse , Prateek Prasanna

Coronary angiography is the gold standard imaging technique for studying and diagnosing coronary artery disease. However, the resulting 2D X-ray projections lose 3D information and exhibit visual ambiguities. In this work, we aim to…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Yifan Wu , Rohit Jena , Mehmet Gulsun , Vivek Singh , Puneet Sharma , James C. Gee

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

By increasing the volume of telemedicine information, the need for medical image compression has become more important. In angiographic images, a small ratio of the entire image usually belongs to the vasculature that provides crucial…

Computer Vision and Pattern Recognition · Computer Science 2018-02-23 Mahdi Ahmadi , Ali Emami , Mohsen Hajabdollahi , S. M. Reza Soroushmehr , Nader Karimi , Shadrokh Samavi , Kayvan Najarian

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

High-quality, large-scale data is essential for robust deep learning models in medical applications, particularly ultrasound image analysis. Diffusion models facilitate high-fidelity medical image generation, reducing the costs associated…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Pooria Ashrafian , Milad Yazdani , Moein Heidari , Dena Shahriari , Ilker Hacihaliloglu

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Large-scale generative models have demonstrated impressive capabilities in producing visually compelling images, with increasing applications in medical imaging. However, they continue to grapple with hallucination challenges and the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Anees Ur Rehman Hashmi , Ibrahim Almakky , Mohammad Areeb Qazi , Santosh Sanjeev , Vijay Ram Papineni , Jagalpathy Jagdish , Mohammad Yaqub

Coronary angiography is considered to be a safe tool for the evaluation of coronary artery disease and perform in approximately 12 million patients each year worldwide. [1] In most cases, angiograms are manually analyzed by a cardiologist.…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Stanislav Filippov , Arsenii Moiseev , Andronenko Andrey

Equivocal 3D lesion segmentation exhibits high inter-observer variability. Conventional deterministic models ignore this aleatoric uncertainty, producing over-confident masks that obscure clinical risks. Conversely, while generative methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Chao Wu , Kangxian Xie , Mingchen Gao

Diffusion models (DMs) have emerged as powerful foundation models for a variety of tasks, with a large focus in synthetic image generation. However, their requirement of large annotated datasets for training limits their applicability in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Guillermo Jimenez-Perez , Pedro Osorio , Josef Cersovsky , Javier Montalt-Tordera , Jens Hooge , Steffen Vogler , Sadegh Mohammadi

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…