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Contrastive learning (CL) aims to learn useful representation without relying on expert annotations in the context of medical image segmentation. Existing approaches mainly contrast a single positive vector (i.e., an augmentation of the…

Computer Vision and Pattern Recognition · Computer Science 2022-03-08 Chenyu You , Ruihan Zhao , Lawrence Staib , James S. Duncan

Modern electronic health records (EHRs) hold immense promise in tracking personalized patient health trajectories through sequential deep learning, owing to their extensive breadth, scale, and temporal granularity. Nonetheless, how to…

Covid-19 global pandemic continues to devastate health care systems across the world. At present, the Covid-19 testing is costly and time-consuming. Chest X-Ray (CXR) testing can be a fast, scalable, and non-invasive method. The existing…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Anirudh Ambati , Shiv Ram Dubey

We develop an approach to learning visual representations that embraces multimodal data, driven by a combination of intra- and inter-modal similarity preservation objectives. Unlike existing visual pre-training methods, which solve a proxy…

Computer Vision and Pattern Recognition · Computer Science 2021-04-28 Xin Yuan , Zhe Lin , Jason Kuen , Jianming Zhang , Yilin Wang , Michael Maire , Ajinkya Kale , Baldo Faieta

Cardiac MRI allows for a comprehensive assessment of myocardial structure, function and tissue characteristics. Here we describe a foundational vision system for cardiac MRI, capable of representing the breadth of human cardiovascular…

In recent years, deep learning-based image analysis methods have been widely applied in computer-aided detection, diagnosis and prognosis, and has shown its value during the public health crisis of the novel coronavirus disease 2019…

CLIP and BiomedCLIP are examples of vision-language foundation models and offer strong cross-modal embeddings; however, they are not optimized for fine-grained medical retrieval tasks, such as retrieving clinically relevant radiology…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zhaohui Liang , Sivaramakrishnan Rajaraman , Niccolo Marini , Zhiyun Xue , Sameer Antani

EEG-based neural decoding models often fail to generalize across acquisition sites due to structured, site-dependent biases implicitly exploited during training. We reformulate cross-site clinical EEG learning as a bias-factorized…

Neurons and Cognition · Quantitative Biology 2026-02-24 Xiaobin Wong , Zhonghua Zhao , Haoran Guo , Zhengyi Liu , Yu Wu , Feng Yan , Zhiren Wang , Sen Song

Chest X-ray (CXR) imaging is one of the most widely used diagnostic modalities in clinical practice, encompassing a broad spectrum of diagnostic tasks. Recent advancements have seen the extensive application of reasoning-based multimodal…

Accurate interpretation of electrocardiogram (ECG) remains challenging due to the scarcity of labeled data and the high cost of expert annotation. Self-supervised learning (SSL) offers a promising solution by enabling models to learn…

Artificial Intelligence · Computer Science 2026-04-14 Zehao Qin , Xiaojian Lin , Ping Zhang , Hongliang Wu , Xinkang Wang , Guangling Liu , Bo Chen , Wenming Yang , Guijin Wang

Electrocardiogram (ECG) monitoring is one of the most powerful technique of cardiovascular disease (CVD) early identification, and the introduction of intelligent wearable ECG devices has enabled daily monitoring. However, due to the need…

Signal Processing · Electrical Eng. & Systems 2024-03-08 Hongxiang Gao , Xingyao Wang , Zhenghua Chen , Min Wu , Jianqing Li , Chengyu Liu

Machine learning holds promise for advancing clinical decision support, yet it remains unclear when multimodal learning truly helps in practice, particularly under modality missingness and fairness constraints. In this work, we conduct a…

Machine Learning · Computer Science 2026-03-02 Kejing Yin , Haizhou Xu , Wenfang Yao , Chen Liu , Zijie Chen , Yui Haang Cheung , William K. Cheung , Jing Qin

Echocardiography (echo) is an ultrasound imaging modality that is widely used for various cardiovascular diagnosis tasks. Due to inter-observer variability in echo-based diagnosis, which arises from the variability in echo image acquisition…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Masoud Mokhtari , Neda Ahmadi , Teresa S. M. Tsang , Purang Abolmaesumi , Renjie Liao

Fast and accurate detection of the disease can significantly help in reducing the strain on the healthcare facility of any country to reduce the mortality during any pandemic. The goal of this work is to create a multimodal system using a…

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

Multi-modal contrastive representation (MCR) of more than three modalities is critical in multi-modal learning. Although recent methods showcase impressive achievements, the high dependence on large-scale, high-quality paired data and the…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Zehan Wang , Ziang Zhang , Luping Liu , Yang Zhao , Haifeng Huang , Tao Jin , Zhou Zhao

Deep learning models have revolutionized medical imaging and diagnostics, yet their opaque nature poses challenges for clinical adoption and trust. Amongst approaches to improve model interpretability, concept-based explanations aim to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Vijay Sadashivaiah , Pingkun Yan , James A. Hendler

Electrocardiography (ECG) analysis is crucial for cardiac diagnosis, yet existing foundation models often fail to capture the periodicity and diverse features required for varied clinical tasks. We propose ECG-MoE, a hybrid architecture…

Artificial Intelligence · Computer Science 2026-03-06 Yuhao Xu , Xiaoda Wang , Yi Wu , Wei Jin , Xiao Hu , Carl Yang

Learning representations of multimodal data that are both informative and robust to missing modalities at test time remains a challenging problem due to the inherent heterogeneity of data obtained from different channels. To address it, we…

Machine Learning · Computer Science 2022-11-21 Petra Poklukar , Miguel Vasco , Hang Yin , Francisco S. Melo , Ana Paiva , Danica Kragic

Recent advancements in non-invasive detection of cardiac hemodynamic instability (CHDI) primarily focus on applying machine learning techniques to a single data modality, e.g. cardiac magnetic resonance imaging (MRI). Despite their…