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Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , Xiu Li , Jayender Jagadeesan

Head and neck squamous cell carcinoma (HNSCC) has one of the highest rates of recurrence cases among solid malignancies. Recurrence rates can be reduced by improving positive margins localization. Frozen section analysis (FSA) of resected…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Qingyun Yang , Fangjie Li , Jiayi Xu , Zixuan Liu , Sindhura Sridhar , Whitney Jin , Jennifer Du , Jon Heiselman , Michael Miga , Michael Topf , Jie Ying Wu

Magnetic Resonance Imaging (MRI) is an essential diagnostic tool for assessing knee injuries. However, manual interpretation of MRI slices remains time-consuming and prone to inter-observer variability. This study presents a systematic…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Justin Yiu , Kushank Arora , Daniel Steinberg , Rohit Ghiya

Image registration is a fundamental task for medical imaging. Resampling of the intensity values is required during registration and better spatial resolution with finer and sharper structures can improve the resampling performance and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-03 Kaicong Sun , Sven Simon

Image registration is a fundamental task that aligns anatomical structures between images. While CNNs perform well, they lack rotation equivariance - a rotated input does not produce a correspondingly rotated output. This hinders…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Arghavan Rezvani , Kun Han , Anthony T. Wu , Pooya Khosravi , Xiaohui Xie

In adaptive radiotherapy, deformable image registration is often conducted between the planning CT and treatment CT (or cone beam CT) to generate a deformation vector field (DVF) for dose accumulation and contour propagation. The auto…

Medical Physics · Physics 2015-06-12 Xuejun Gu , Bin Dong , Jing Wang , John Yordy , Loren Mell , Xun Jia , Steve B. Jiang

Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Ning Zhang , Susan Francis , Rayaz Malik , Xin Chen

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

Purpose: This study aims to explore training strategies to improve convolutional neural network-based image-to-image deformable registration for abdominal imaging. Methods: Different training strategies, loss functions, and transfer…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Javier Pérez de Frutos , André Pedersen , Egidijus Pelanis , David Bouget , Shanmugapriya Survarachakan , Thomas Langø , Ole-Jakob Elle , Frank Lindseth

Cone-beam CT (CBCT)-based online adaptive radiotherapy calls for accurate auto-segmentation to reduce the time cost for physicians to edit contours. However, deep learning (DL)-based direct segmentation of CBCT images is a challenging task,…

Medical Physics · Physics 2023-02-22 Xiao Liang , Howard Morgan , Ti Bai , Michael Dohopolski , Dan Nguyen , Steve Jiang

Segmentation algorithms for medical images are widely studied for various clinical and research purposes. In this paper, we propose a new and efficient method for medical image segmentation under noisy labels. The method operates under a…

Image and Video Processing · Electrical Eng. & Systems 2021-06-18 Ziyang Wang , Zhengdong Zhang , Irina Voiculescu

Magnetic resonance imaging (MRI) is increasingly utilized for image-guided radiotherapy due to its outstanding soft-tissue contrast and lack of ionizing radiation. However, geometric distortions caused by gradient nonlinearity (GNL) limit…

State-of-the-art deep learning methods for image processing are evolving into increasingly complex meta-architectures with a growing number of modules. Among them, region-based fully convolutional networks (R-FCN) and deformable…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Stephen Morrell , Zbigniew Wojna , Can Son Khoo , Sebastien Ourselin , Juan Eugenio Iglesias

We propose contrastive coding to learn shared, dense image representations, referred to as CoMIRs (Contrastive Multimodal Image Representations). CoMIRs enable the registration of multimodal images where existing registration methods often…

Computer Vision and Pattern Recognition · Computer Science 2021-01-14 Nicolas Pielawski , Elisabeth Wetzer , Johan Öfverstedt , Jiahao Lu , Carolina Wählby , Joakim Lindblad , Nataša Sladoje

Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Amir Sadikov , Xinlei Pan , Hannah Choi , Lanya T. Cai , Pratik Mukherjee

Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Hyungjin Chung , Eun Sun Lee , Jong Chul Ye

Effective and accurate diagnosis of Alzheimer's disease (AD) or mild cognitive impairment (MCI) can be critical for early treatment and thus has attracted more and more attention nowadays. Since first introduced, machine learning methods…

Computer Vision and Pattern Recognition · Computer Science 2014-04-29 Fayao Liu , Chunhua Shen

Diffeomorphic deformable multi-modal image registration is a challenging task which aims to bring images acquired by different modalities to the same coordinate space and at the same time to preserve the topology and the invertibility of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Vasiliki Sideri-Lampretsa , Georgios Kaissis , Daniel Rueckert

The correlation of optical measurements with a correct pathology label is often hampered by imprecise registration caused by deformations in histology images. This study explores an automated multi-modal image registration technique…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Lianne Feenstra , Maud Lambregts , Theo J. M Ruers , Behdad Dashtbozorg

Dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) is a widely used multi-phase technique routinely used in clinical practice. DCE and similar datasets of dynamic medical data tend to contain redundant information on the…