English
Related papers

Related papers: Conceptual Modelling for Life Sciences Based on Sy…

200 papers

Modeling of work systems occurs for all sorts of reasons. Requirements need to be expressed. A pre-existing situation may need to be charted and analyzed. Early design decisions may be captured using architecture principles. Detailed design…

Software Engineering · Computer Science 2021-05-19 Henderik A. Proper

Software-intensive Systems-of-Systems (SoS) refer to an arrangement of managerially and operationally independent systems(i.e., constituent systems), which work collaboratively towards the achievement of global missions. Because some SoS…

Software Engineering · Computer Science 2020-07-15 Cristiane Aparecida Lana , Milena Guessi , Pablo Oliveira Antonino , Dieter Rombach , Elisa Yumi NakagawaA

The advent of Large Language Models (LLMs) represents a turning point in the theoretical foundations of Information Systems Engineering. Beyond their technical significance, LLMs challenge the ontological, epistemological, and semiotic…

Software Engineering · Computer Science 2026-03-19 José Palazzo Moreira de Oliveira

There is a growing need for better development methods and tools to keep up with the increasing complexity of new software systems. New types of user interfaces, the need for intelligent components, sustainability concerns, ... bring new…

Software Engineering · Computer Science 2024-02-29 Jordi Cabot

With the rapid development of Large Language Models (LLMs), AI agents have demonstrated increasing proficiency in scientific tasks, ranging from hypothesis generation and experimental design to manuscript writing. Such agent systems are…

Since the turn of the millennium, computational modelling of biological systems has evolved remarkably and sees matured use spanning basic and clinical research. While the topic of the peri-millennial debate about the virtues and…

Quantitative Methods · Quantitative Biology 2025-08-05 Axel Loewe , Peter J. Hunter , Peter Kohl

Mathematical models of complex social systems can enrich social scientific theory, inform interventions, and shape policy. From voting behavior to economic inequality and urban development, such models influence decisions that affect…

In this chapter, I review the main methods and techniques of complex systems science. As a first step, I distinguish among the broad patterns which recur across complex systems, the topics complex systems science commonly studies, the tools…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Cosma Rohilla Shalizi

Cognitive science faces ongoing challenges in research integration, formalization, conceptual clarity, and other areas, in part due to its multifaceted and interdisciplinary nature. Recent advances in artificial intelligence, particularly…

Artificial Intelligence · Computer Science 2026-03-03 Dirk U. Wulff , Rui Mata

Declarative modeling uses symbolic expressions to represent models. With such expressions one can formalize high-level mathematical computations on models that would be difficult or impossible to perform directly on a lower-level simulation…

Quantitative Methods · Quantitative Biology 2019-07-02 Eric Mjolsness

This paper is a first step to chase the ambitious objective of developing a mathmatical theory of living systems. The contents refer modeling large systems of interacting living entities with the aim of describing their collective behaviors…

The plethora of existing data models and specific data modeling techniques is not only confusing but leads to complex, eclectic and inefficient designs of systems for data management and analytics. The main goal of this paper is to describe…

Databases · Computer Science 2016-06-08 Alexandr Savinov

Substantial efforts have been made in developing various Decision Modeling formalisms, both from industry and academia. A challenging problem is that of expressing decision knowledge in the context of incomplete knowledge. In such contexts,…

Artificial Intelligence · Computer Science 2023-12-19 Đorđe Marković , Simon Vandevelde , Linde Vanbesien , Joost Vennekens , Marc Denecker

Advances in science are being sought in newly available opportunities to collect massive quantities of data about complex systems. While key advances are being made in detailed mapping of systems, how to relate this data to solving many of…

Physics and Society · Physics 2016-04-05 Yaneer Bar-Yam

Network neuroscience is the emerging discipline concerned with investigating the complex patterns of interconnections found in neural systems, and to identify principles with which to understand them. Within this discipline, one…

Neurons and Cognition · Quantitative Biology 2017-08-29 Richard F. Betzel , Danielle S. Bassett

Biological systems are often modeled as a system of ordinary differential equations (ODEs) with time-invariant parameters. However, cell signaling events or pharmacological interventions may alter the cellular state and induce multi-mode…

Quantitative Methods · Quantitative Biology 2020-04-28 Bing Liu

The role of information systems (IS) as representations of real-world systems is changing in an increasingly digitalized world, suggesting that conceptual modeling is losing its relevance to the IS field. We argue the opposite: Conceptual…

Human-Computer Interaction · Computer Science 2025-06-24 J. Recker , R. Lukyanenko , M. A. Jabbari , B. M. Samuel , A. Castellanos

What is a system? Is one of those questions that is yet not clear to most individuals in this world. A system is an assemblage of interacting, interrelated and interdependent components forming a complex and integrated whole with an…

Computers and Society · Computer Science 2021-12-03 Avishek Choudhury , Onur Asan , Mo Mansouri

This position paper argues that the image processing community should broaden its focus from purely model-centric development to include agentic system design as an essential complementary paradigm. While deep learning has significantly…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Jinjin Gu

The concept of random dynamical system is a comparatively recent development combining ideas and methods from the well developed areas of probability theory and dynamical systems. Due to our inaccurate knowledge of the particular physical…

Dynamical Systems · Mathematics 2007-05-23 Vitor Araujo