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Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

Prediction of genetic biomarkers, e.g., microsatellite instability in colorectal cancer is crucial for clinical decision making. But, two primary challenges hamper accurate prediction: (1) It is difficult to construct a pathology-aware…

Quantitative Methods · Quantitative Biology 2026-03-31 Ling Zhang , Boxiang Yun , Ting Jin , Qingli Li , Xinxing Li , Yan Wang

Encoding whole slide images (WSI) as graphs is well motivated since it makes it possible for the gigapixel resolution WSI to be represented in its entirety for the purpose of graph learning. To this end, WSIs can be broken into smaller…

Image and Video Processing · Electrical Eng. & Systems 2023-06-16 Milan Aryal , Nasim Yahyasoltani

Cross-modal information retrieval aims to find heterogeneous data of various modalities from a given query of one modality. The main challenge is to map different modalities into a common semantic space, in which distance between concepts…

Information Retrieval · Computer Science 2018-02-14 Jing Yu , Yuhang Lu , Zengchang Qin , Yanbing Liu , Jianlong Tan , Li Guo , Weifeng Zhang

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova

Existing WSI analysis methods lie on the consensus that histopathological characteristics of tumors are significant guidance for cancer diagnostics. Particularly, as the evolution of cancers is a continuous process, the correlations and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Tong Shu , Jun Shi , Dongdong Sun , Zhiguo Jiang , Yushan Zheng

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Lifelong learning on Whole Slide Images (WSIs) aims to train or fine-tune a unified model sequentially on cancer-related tasks, reducing the resources and effort required for data transfer and processing, especially given the gigabyte-scale…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Doanh C. Bui , Ba Hung Ngo , Hoai Luan Pham , Khang Nguyen , Maï K. Nguyen , Yasuhiko Nakashima

Self-supervised learning is an efficient pre-training method for medical image analysis. However, current research is mostly confined to specific-modality data pre-training, consuming considerable time and resources without achieving…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Yiwen Ye , Yutong Xie , Jianpeng Zhang , Ziyang Chen , Qi Wu , Yong Xia

Whole slide image (WSI) analysis has become increasingly important in the medical imaging community, enabling automated and objective diagnosis, prognosis, and therapeutic-response prediction. However, in clinical practice, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Yanyan Huang , Weiqin Zhao , Shujun Wang , Yu Fu , Yuming Jiang , Lequan Yu

The Vision Foundation Model has recently gained attention in medical image analysis. Its zero-shot learning capabilities accelerate AI deployment and enhance the generalizability of clinical applications. However, segmenting pathological…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Can Cui , Ruining Deng , Junlin Guo , Quan Liu , Tianyuan Yao , Haichun Yang , Yuankai Huo

In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Zhi-Bo Liu , Xiaobo Pang , Jizhao Wang , Shuai Liu , Chen Li

Content generation modeling has emerged as a promising direction in computational pathology, offering capabilities such as data-efficient learning, synthetic data augmentation, and task-oriented generation across diverse diagnostic tasks.…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Yuan Zhang , Xinfeng Zhang , Xiaoming Qi , Xinyu Wu , Feng Chen , Guanyu Yang , Huazhu Fu

Survival prediction is a complex ordinal regression task that aims to predict the survival coefficient ranking among a cohort of patients, typically achieved by analyzing patients' whole slide images. Existing deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Minghao Han , Xukun Zhang , Dingkang Yang , Tao Liu , Haopeng Kuang , Jinghui Feng , Lihua Zhang

This work tackles the problem of generating a medical report for multi-image panels. We apply our solution to the Renal Direct Immunofluorescence (RDIF) assay which requires a pathologist to generate a report based on observations across…

Computer Vision and Pattern Recognition · Computer Science 2020-07-03 Sam Maksoud , Arnold Wiliem , Kun Zhao , Teng Zhang , Lin Wu , Brian C. Lovell

The study of decoding visual neural information faces challenges in generalizing single-subject decoding models to multiple subjects, due to individual differences. Moreover, the limited availability of data from a single subject has a…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Qiongyi Zhou , Changde Du , Shengpei Wang , Huiguang He

Despite the progress of radiology report generation (RRG), existing works face two challenges: 1) The performances in clinical efficacy are unsatisfactory, especially for lesion attributes description; 2) the generated text lacks…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Haibo Jin , Haoxuan Che , Sunan He , Hao Chen

Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Radiology Report Generation (RRG) aims to produce accurate and coherent diagnostics from medical images. Although large vision language models (LVLM) improve report fluency and accuracy, they exhibit hallucinations, generating plausible yet…

Computation and Language · Computer Science 2026-02-05 Ruixiao Yang , Yuanhe Tian , Xu Yang , Huiqi Li , Yan Song

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King
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