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Latent factor models are the canonical statistical tool for exploratory analyses of low-dimensional linear structure for an observation matrix with p features across n samples. We develop a structured Bayesian group factor analysis model…

Methodology · Statistics 2015-11-12 Shiwen Zhao , Chuan Gao , Sayan Mukherjee , Barbara E Engelhardt

Metabolomics is the study of small molecules in biological samples. Metabolomics data are typically high-dimensional and contain highly correlated variables and frequent missing values. Both missing at random (MAR) data, due to acquisition…

Despite the fact that they do not consider the temporal nature of data, classic dimensionality reduction techniques, such as PCA, are widely applied to time series data. In this paper, we introduce a factor decomposition specific for time…

Machine Learning · Statistics 2014-06-17 Diego Vidaurre , Iead Rezek , Samuel L. Harrison , Stephen S. Smith , Mark Woolrich

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has transformed genomic research by enabling high-throughput gene expression profiling while preserving spatial context. Identifying spatial…

Methodology · Statistics 2024-08-27 Bencong Zhu , Guanyu Hu , Xiaodan Fan , Qiwei Li

The analysis of clinical questionnaire data comes with many inherent challenges. These challenges include the handling of data with missing fields, as well as the overall interpretation of a dataset with many fields of different scales and…

Machine Learning · Computer Science 2021-08-04 Connor J. McLaughlin , Efi G. Kokkotou , Jean A. King , Lisa A. Conboy , Ali Yousefi

A major challenge in nuclear fusion research is the coherent combination of data from heterogeneous diagnostics and modelling codes for machine control and safety as well as physics studies. Measured data from different diagnostics often…

Although variable selection is one of the most popular areas of modern statistical research, much of its development has taken place in the classical paradigm compared to the Bayesian counterpart. Somewhat surprisingly, both the paradigms…

Statistics Theory · Mathematics 2021-05-27 Minerva Mukhopadhyay , Sourabh Bhattacharya

This paper explores the use of factor graphs as an inference and analysis tool for Bayesian peer-to-peer decentralized data fusion. We propose a framework by which agents can each use local factor graphs to represent relevant partitions of…

Robotics · Computer Science 2023-03-07 Ofer Dagan , Nisar R. Ahmed

With advances in high-resolution mass spectrometry technologies, metabolomics data are increasingly used to investigate biological mechanisms underlying associations between exposures and health outcomes in clinical and epidemiological…

Applications · Statistics 2025-03-19 Yuzi Zhang , Donghai Liang , Youran Tan , Anne L. Dunlop , Howard H. Chang

For most problems in science and engineering we can obtain data sets that describe the observed system from various perspectives and record the behavior of its individual components. Heterogeneous data sets can be collectively mined by data…

Machine Learning · Computer Science 2015-02-09 Marinka Žitnik , Blaž Zupan

Clustering is commonly performed as an initial analysis step for uncovering structure in 'omics datasets, e.g. to discover molecular subtypes of disease. The high-throughput, high-dimensional nature of these datasets means that they provide…

Methodology · Statistics 2023-03-02 Paul D. W. Kirk , Filippo Pagani , Sylvia Richardson

Bayesian learning has emerged as a compelling and vital research direction in the field of structural dynamics, offering a probabilistic lens to understand and refine the analysis of complex dynamical systems. This review meticulously…

Data Analysis, Statistics and Probability · Physics 2025-06-03 Wang-Ji Yan , Lin-Feng Mei , Yuan-Wei Yin , Jiang Mo , Costas Papadimitriou , Ka-Veng Yuen , Michael Beer

High-dimensional data can be useful for causal inference by providing many confounders that may bolster the plausibility of the ignorability assumption. Propensity score methods are powerful tools for causal inference, are popular in health…

Methodology · Statistics 2017-10-10 Jacob Spertus , Sharon-Lise Normand

We propose a novel classification model for weak signal data, building upon a recent model for Bayesian multi-view learning, Group Factor Analysis (GFA). Instead of assuming all data to come from a single GFA model, we allow latent…

Machine Learning · Statistics 2016-06-08 Sami Remes , Tommi Mononen , Samuel Kaski

We propose a multiple imputation method based on principal component analysis (PCA) to deal with incomplete continuous data. To reflect the uncertainty of the parameters from one imputation to the next, we use a Bayesian treatment of the…

Methodology · Statistics 2015-08-20 Vincent Audigier , François Husson , Julie Josse

Bayesian matrix factorization (BMF) is a powerful tool for producing low-rank representations of matrices and for predicting missing values and providing confidence intervals. Scaling up the posterior inference for massive-scale matrices is…

Machine Learning · Statistics 2019-02-28 Xiangju Qin , Paul Blomstedt , Eemeli Leppäaho , Pekka Parviainen , Samuel Kaski

Estimating the marginal and joint densities of the long-term average intakes of different dietary components is an important problem in nutritional epidemiology. Since these variables cannot be directly measured, data are usually collected…

Methodology · Statistics 2022-05-18 Abhra Sarkar

Differential analysis is a routine procedure in the statistical analysis toolbox across many applied fields, including quantitative proteomics, the main illustration of the present paper. The state-of-the-art limma approach uses a…

Methodology · Statistics 2025-12-12 Marie Chion , Arthur Leroy

Diet is a risk factor for many diseases. In nutritional epidemiology, studying reproducible dietary patterns is critical to reveal important associations with health. However, it is challenging: diverse cultural and ethnic backgrounds may…

Applications · Statistics 2025-02-10 Roberta De Vito , Alejandra Avalos-Pacheco

Federated learning (FL) demonstrates its advantages in integrating distributed infrastructure, communication, computing and learning in a privacy-preserving manner. However, the robustness and capabilities of existing FL methods are…

Machine Learning · Computer Science 2023-04-27 Longbing Cao , Hui Chen , Xuhui Fan , Joao Gama , Yew-Soon Ong , Vipin Kumar
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