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Medical vision-language pretraining models (VLPM) have achieved remarkable progress in fusing chest X-rays (CXR) with clinical texts, introducing image-text data binding approaches that enable zero-shot learning and downstream clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yuan Gao , Sangwook Kim , David E Austin , Chris McIntosh

Recent advancements in biology and chemistry have leveraged multi-modal learning, integrating molecules and their natural language descriptions to enhance drug discovery. However, current pre-training frameworks are limited to two…

Machine Learning · Computer Science 2025-02-05 Teng Xiao , Chao Cui , Huaisheng Zhu , Vasant G. Honavar

Pre-trained models, e.g., from ImageNet, have proven to be effective in boosting the performance of many downstream applications. It is too demanding to acquire large-scale annotations to build such models for medical imaging. Meanwhile,…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Xiaosong Wang , Ziyue Xu , Leo Tam , Dong Yang , Daguang Xu

Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiaogen Zhou , Yiyou Sun , Min Deng , Winnie Chiu Wing Chu , Qi Dou

Utilizing a shared embedding space, emerging multimodal models exhibit unprecedented zero-shot capabilities. However, the shared embedding space could lead to new vulnerabilities if different modalities can be misaligned. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Shaeke Salman , Md Montasir Bin Shams , Xiuwen Liu

Semi-supervised learning addresses the issue of limited annotations in medical images effectively, but its performance is often inadequate for complex backgrounds and challenging tasks. Multi-modal fusion methods can significantly improve…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Dongdong Meng , Sheng Li , Hao Wu , Guoping Wang , Xueqing Yan

Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Qinghua Lin , Guang-Hai Liu , Zuoyong Li , Yang Li , Yuting Jiang , Xiang Wu

Existing vision-text contrastive learning like CLIP aims to match the paired image and caption embeddings while pushing others apart, which improves representation transferability and supports zero-shot prediction. However, medical…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Zifeng Wang , Zhenbang Wu , Dinesh Agarwal , Jimeng Sun

Multimodal medical image fusion plays a crucial role in medical diagnosis by integrating complementary information from different modalities to enhance image readability and clinical applicability. However, existing methods mainly follow…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Haozhe Xiang , Han Zhang , Yu Cheng , Xiongwen Quan , Wanwan Huang

Foundation models have recently gained tremendous popularity in medical image analysis. State-of-the-art methods leverage either paired image-text data via vision-language pre-training or unpaired image data via self-supervised pre-training…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Lei Zhu , Jun Zhou , Rick Siow Mong Goh , Yong Liu

Within the domain of medical analysis, extensive research has explored the potential of mutual learning between Masked Autoencoders(MAEs) and multimodal data. However, the impact of MAEs on intermodality remains a key challenge. We…

Image and Video Processing · Electrical Eng. & Systems 2024-06-03 Lei Li , Tianfang Zhang , Xinglin Zhang , Jiaqi Liu , Bingqi Ma , Yan Luo , Tao Chen

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Taha Koleilat , Hojat Asgariandehkordi , Omid Nejati Manzari , Berardino Barile , Yiming Xiao , Hassan Rivaz

Existing contrastive language-image pre-training aims to learn a joint representation by matching abundant image-text pairs. However, the number of image-text pairs in medical datasets is usually orders of magnitude smaller than that in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-04 Jiarun Liu , Hong-Yu Zhou , Cheng Li , Weijian Huang , Hao Yang , Yong Liang , Shanshan Wang

Contrastive Language-Image Pre-training (CLIP), a simple yet effective pre-training paradigm, successfully introduces text supervision to vision models. It has shown promising results across various tasks due to its generalizability and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Zihao Zhao , Yuxiao Liu , Han Wu , Mei Wang , Yonghao Li , Sheng Wang , Lin Teng , Disheng Liu , Zhiming Cui , Qian Wang , Dinggang Shen

We present ImageBind, an approach to learn a joint embedding across six different modalities - images, text, audio, depth, thermal, and IMU data. We show that all combinations of paired data are not necessary to train such a joint…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Rohit Girdhar , Alaaeldin El-Nouby , Zhuang Liu , Mannat Singh , Kalyan Vasudev Alwala , Armand Joulin , Ishan Misra

Large-scale natural image-text datasets, especially those automatically collected from the web, often suffer from loose semantic alignment due to weak supervision, while medical datasets tend to have high cross-modal correlation but low…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Shengzhu Yang , Jiawei Du , Shuai Lu , Weihang Zhang , Ningli Wang , Huiqi Li

Cross-modal retrieval between visual data and natural language description remains a long-standing challenge in multimedia. While recent image-text retrieval methods offer great promise by learning deep representations aligned across…

Joint embeddings between medical imaging modalities and associated radiology reports have the potential to offer significant benefits to the clinical community, ranging from cross-domain retrieval to conditional generation of reports to the…

Machine Learning · Computer Science 2018-11-28 Tzu-Ming Harry Hsu , Wei-Hung Weng , Willie Boag , Matthew McDermott , Peter Szolovits

Although image captioning models have made significant advancements in recent years, the majority of them heavily depend on high-quality datasets containing paired images and texts which are costly to acquire. Previous works leverage the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Zhiyue Liu , Jinyuan Liu , Fanrong Ma

Contrastive Language and Image Pairing (CLIP), a transformative method in multimedia retrieval, typically trains two neural networks concurrently to generate joint embeddings for text and image pairs. However, when applied directly, these…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Konstantin Schall , Kai Uwe Barthel , Nico Hezel , Klaus Jung
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