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Vision-language foundation models (VLMs) have shown great potential in feature transfer and generalization across a wide spectrum of medical-related downstream tasks. However, fine-tuning these models is resource-intensive due to their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Ye Du , Nanxi Yu , Shujun Wang

The integration of artificial intelligence in medical imaging has shown tremendous potential, yet the relationship between pre-trained knowledge and performance in cross-modality learning remains unclear. This study investigates how…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yang Yan , Bingqing Yue , Qiaxuan Li , Man Huang , Jingyu Chen , Zhenzhong Lan

Explainable AI seeks to bring light to the decision-making processes of black-box models. Traditional saliency-based methods, while highlighting influential data segments, often lack semantic understanding. Recent advancements, such as…

Artificial Intelligence · Computer Science 2023-10-12 Bo Pan , Zhenke Liu , Yifei Zhang , Liang Zhao

Concept Bottleneck Models (CBMs) enhance interpretability by explaining predictions through human-understandable concepts but typically assume that training and test data share the same distribution. This assumption often fails under domain…

Machine Learning · Computer Science 2025-05-09 Xinyue Xu , Yueying Hu , Hui Tang , Yi Qin , Lu Mi , Hao Wang , Xiaomeng Li

Deep learning models have gained remarkable performance on a variety of image classification tasks. However, many models suffer from limited performance in clinical or medical settings when data are imbalanced. To address this challenge, we…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Margarita L. Zuley , Shandong Wu

Medical coding, the translation of unstructured clinical text into standardized medical codes, is a crucial but time-consuming healthcare practice. Though large language models (LLM) could automate the coding process and improve the…

Computation and Language · Computer Science 2025-03-25 John Wu , David Wu , Jimeng Sun

Deep learning has demonstrated expert-level performance in melanoma classification, positioning it as a powerful tool in clinical dermatology. However, model opacity and the lack of interpretability remain critical barriers to clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Junwen Zheng , Xinran Xu , Li Rong Wang , Chang Cai , Lucinda Siyun Tan , Dingyuan Wang , Hong Liang Tey , Xiuyi Fan

Human-interpretable predictions are essential for deploying AI in medical imaging, yet most interpretable-by-design (IBD) frameworks require concept annotations for training data, which are costly and impractical to obtain in clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Md Nahiduzzaman , Steven Korevaar , Alireza Bab-Hadiashar , Ruwan Tennakoon

Concept Bottleneck Models (CBMs) promote interpretability by grounding predictions in human-understandable concepts. However, existing CBMs typically fix their task predictor to a single linear or Boolean expression, limiting both…

Deep Learning (DL) requires a large amount of training data to provide quality outcomes. However, the field of medical imaging suffers from the lack of sufficient data for properly training DL models because medical images require manual…

Computer Vision and Pattern Recognition · Computer Science 2021-10-14 Laith Alzubaidi , J. Santamaría , Mohamed Manoufali , Beadaa Mohammed , Mohammed A. Fadhel , Jinglan Zhang , Ali H. Al-Timemy , Omran Al-Shamma , Ye Duan

As AI models grow larger, the demand for accountability and interpretability has become increasingly critical for understanding their decision-making processes. Concept Bottleneck Models (CBMs) have gained attention for enhancing…

Machine Learning · Computer Science 2024-10-10 Angelos Ragkousis , Sonali Parbhoo

Few-shot learning has been studied to adapt models to tasks with very few samples. It holds profound significance, particularly in clinical tasks, due to the high annotation cost of medical images. Several works have explored few-shot…

Computer Vision and Pattern Recognition · Computer Science 2024-02-06 Kaipeng Zheng , Weiran Huang , Lichao Sun

State-of-the-art, high capacity deep neural networks not only require large amounts of labelled training data, they are also highly susceptible to label errors in this data, typically resulting in large efforts and costs and therefore…

Machine Learning · Computer Science 2020-07-20 Christian Haase-Schütz , Rainer Stal , Heinz Hertlein , Bernhard Sick

Open-ended grading is central to equitable and personalized education, yet manual grading remains time-consuming and costly, underscoring the need for automated grading systems. Although recent neural and large language model (LLM) based…

Computers and Society · Computer Science 2026-05-28 Chengshuai Zhao , Fan Zhang , Kumar Satvik Chaudhary , Yiwen Li , Lo Pang-Yun Ting , Ying-Chih Chen , Huan Liu

Developing high-performing, yet interpretable models remains a critical challenge in modern AI. Concept-based models (CBMs) attempt to address this by extracting human-understandable concepts from a global encoding (e.g., image encoding)…

Machine Learning · Computer Science 2025-10-08 David Steinmann , Wolfgang Stammer , Antonia Wüst , Kristian Kersting

Machine learning models that first learn a representation of a domain in terms of human-understandable concepts, then use it to make predictions, have been proposed to facilitate interpretation and interaction with models trained on…

Machine Learning · Computer Science 2020-12-08 Isaac Lage , Finale Doshi-Velez

In this paper, we introduce an explainable algorithm designed from a multi-modal foundation model, that performs fast and explainable image classification. Drawing inspiration from CLIP-based Concept Bottleneck Models (CBMs), our method…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Rémi Kazmierczak , Eloïse Berthier , Goran Frehse , Gianni Franchi

Concept Bottleneck Models (CBMs) ground predictions in human-understandable concepts but face fundamental limitations: the absence of a metric to pre-evaluate concept relevance, the "linearity problem" causing recent CBMs to bypass the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Merve Tapli , Quentin Bouniot , Wolfgang Stammer , Zeynep Akata , Emre Akbas

Artificial intelligence (AI) is transforming scientific research, with explainable AI methods like concept-based models (CMs) showing promise for new discoveries. However, in molecular science, CMs are less common than black-box models like…

Artificial Intelligence · Computer Science 2024-12-17 Zimin Zhang , Qianli Wu , Botao Xia , Fang Sun , Ziniu Hu , Yizhou Sun , Shichang Zhang

The pursuit of decision safety in clinical applications highlights the potential of concept-based methods in medical imaging. While these models offer active interpretability, they often suffer from concept leakages, where unintended…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Yibo Gao , Hangqi Zhou , Zheyao Gao , Bomin Wang , Shangqi Gao , Sihan Wang , Xiahai Zhuang