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Population dynamics in fields such as molecular biology, epidemiology, and ecology exhibit highly stochastic and non-linear behaviour. In gene regulatory systems in particular, oscillations and multi-stability are especially common. Despite…

Quantitative Methods · Quantitative Biology 2026-05-13 Frederick Truman-Williams , Giorgos Minas

Backpropagation is widely used to train artificial neural networks, but its relationship to synaptic plasticity in the brain is unknown. Some biological models of backpropagation rely on feedback projections that are symmetric with…

Neurons and Cognition · Quantitative Biology 2023-02-08 Navid Shervani-Tabar , Robert Rosenbaum

Over the last four decades, the amazing success of deep learning has been driven by the use of Stochastic Gradient Descent (SGD) as the main optimization technique. The default implementation for the computation of the gradient for SGD is…

Neural and Evolutionary Computing · Computer Science 2024-12-31 Qianli Liao , Liu Ziyin , Yulu Gan , Brian Cheung , Mark Harnett , Tomaso Poggio

Recurrent neural network-based reinforcement learning systems are capable of complex motor control tasks such as locomotion and manipulation, however, much of their underlying mechanisms still remain difficult to interpret. Our aim is to…

Robotics · Computer Science 2023-06-29 Eugene R. Rush , Christoffer Heckman , Kaushik Jayaram , J. Sean Humbert

The ability to achieve coordinated behavior --engineered or emergent-- on networked systems has attracted widespread interest over several fields. This has led to remarkable advances on the development of a theoretical understanding of the…

Systems and Control · Computer Science 2019-09-16 Hancheng Min , Enrique Mallada

The inclusion of a macroscopic adaptive threshold is studied for the retrieval dynamics of both layered feedforward and fully connected neural network models with synaptic noise. These two types of architectures require a different method…

Disordered Systems and Neural Networks · Physics 2007-08-03 D. Bolle , R. Heylen

Continual learning of deep neural networks is a key requirement for scaling them up to more complex applicative scenarios and for achieving real lifelong learning of these architectures. Previous approaches to the problem have considered…

Machine Learning · Computer Science 2020-06-25 Jary Pomponi , Simone Scardapane , Vincenzo Lomonaco , Aurelio Uncini

Neural network has attracted great attention for a long time and many researchers are devoted to improve the effectiveness of neural network training algorithms. Though stochastic gradient descent (SGD) and other explicit gradient-based…

Optimization and Control · Mathematics 2020-02-11 Ren Liu , Xiaoqun Zhang

Deep neural networks have been shown to achieve state-of-the-art performance in several machine learning tasks. Stochastic Gradient Descent (SGD) is the preferred optimization algorithm for training these networks and asynchronous SGD…

Machine Learning · Computer Science 2016-04-06 Wei Zhang , Suyog Gupta , Xiangru Lian , Ji Liu

Variational inference with normalizing flows (NFs) is an increasingly popular alternative to MCMC methods. In particular, NFs based on coupling layers (Real NVPs) are frequently used due to their good empirical performance. In theory,…

Machine Learning · Statistics 2024-02-27 Daniel Andrade

Biological and artificial neural systems form high-dimensional neural representations that underpin their computational capabilities. Methods for quantifying geometric similarity in neural representations have become a popular tool for…

Neurons and Cognition · Quantitative Biology 2024-12-20 Amin Nejatbakhsh , Victor Geadah , Alex H. Williams , David Lipshutz

We introduce a novel framework for the estimation of the posterior distribution over the weights of a neural network, based on a new probabilistic interpretation of adaptive optimisation algorithms such as AdaGrad and Adam. We demonstrate…

Machine Learning · Statistics 2020-07-21 Samuel Kessler , Arnold Salas , Vincent W. C. Tan , Stefan Zohren , Stephen Roberts

Despite the impressive performance of deep neural networks (DNNs) on numerous vision tasks, they still exhibit yet-to-understand uncouth behaviours. One puzzling behaviour is the subtle sensitive reaction of DNNs to various noise attacks.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Modar Alfadly , Adel Bibi , Bernard Ghanem

Robust machine learning for regulatory genomics is studied under biologically and technically induced distribution shifts. Deep convolutional and attention based models achieve strong in distribution performance on DNA regulatory sequence…

Genomics · Quantitative Biology 2026-02-20 Yiyao Yang

Self-paced learning and hard example mining re-weight training instances to improve learning accuracy. This paper presents two improved alternatives based on lightweight estimates of sample uncertainty in stochastic gradient descent (SGD):…

Machine Learning · Statistics 2018-01-09 Haw-Shiuan Chang , Erik Learned-Miller , Andrew McCallum

We develop an algorithm for systematic design of a large artificial neural network using a progression property. We find that some non-linear functions, such as the rectifier linear unit and its derivatives, hold the property. The…

Neural and Evolutionary Computing · Computer Science 2017-10-24 Saikat Chatterjee , Alireza M. Javid , Mostafa Sadeghi , Partha P. Mitra , Mikael Skoglund

The stochastic gradient descent (SGD) algorithm is the algorithm we use to train neural networks. However, it remains poorly understood how the SGD navigates the highly nonlinear and degenerate loss landscape of a neural network. In this…

Machine Learning · Computer Science 2025-06-13 Liu Ziyin , Hongchao Li , Masahito Ueda

A new dynamic latent space eigenmodel (LSM) is proposed for weighted temporal networks. The model accommodates integer-valued weights, excess of zeros, time-varying node positions (features), and time-varying network sparsity. The latent…

Methodology · Statistics 2026-04-15 Roberto Casarin , Matteo Iacopini , Antonio Peruzzi

We characterize the connectivity structure of feed-forward, deep neural networks (DNNs) using network motif theory. To address whether a particular motif distribution is characteristic of the training task, or function of the DNN, we…

Machine Learning · Computer Science 2024-03-05 Olivia T. Zahn , Thomas L. Daniel , J. Nathan Kutz

Many natural systems, such as neurons firing in the brain or basketball teams traversing a court, give rise to time series data with complex, nonlinear dynamics. We can gain insight into these systems by decomposing the data into segments…

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