English
Related papers

Related papers: Improving Genomic Models via Task-Specific Self-Pr…

200 papers

Pretrained language models have served as important backbones for natural language processing. Recently, in-domain pretraining has been shown to benefit various domain-specific downstream tasks. In the biomedical domain, natural language…

Computation and Language · Computer Science 2022-04-25 Hongyi Yuan , Zheng Yuan , Ruyi Gan , Jiaxing Zhang , Yutao Xie , Sheng Yu

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Deep learning methods have advanced quickly in brain imaging analysis over the past few years, but they are usually restricted by the limited labeled data. Pre-trained model on unlabeled data has presented promising improvement in feature…

Neurons and Cognition · Quantitative Biology 2024-08-22 Jinlong Hu , Yangmin Huang , Nan Wang , Shoubin Dong

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

Adapting general multimodal large language models (MLLMs) to specific domains, such as scientific and industrial fields, is highly significant in promoting their practical applications. This paper systematically investigates domain…

Computation and Language · Computer Science 2025-08-28 Daixuan Cheng , Shaohan Huang , Ziyu Zhu , Xintong Zhang , Wayne Xin Zhao , Zhongzhi Luan , Bo Dai , Zhenliang Zhang

As language models scale up, it becomes increasingly expensive to verify research ideas because conclusions on small models do not trivially transfer to large ones. A possible solution is to establish a generic system that accurately…

Computation and Language · Computer Science 2024-04-09 Yiqun Yao , Siqi fan , Xiusheng Huang , Xuezhi Fang , Xiang Li , Ziyi Ni , Xin Jiang , Xuying Meng , Peng Han , Shuo Shang , Kang Liu , Aixin Sun , Yequan Wang

Gene transformer models such as Nucleotide Transformer, DNABert, and LOGO are trained to learn optimal gene sequence representations by using the Masked Language Modeling (MLM) training objective over the complete Human Reference Genome.…

Computation and Language · Computer Science 2024-10-23 Soumyadeep Roy , Shamik Sural , Niloy Ganguly

Computational pathology can lead to saving human lives, but models are annotation hungry and pathology images are notoriously expensive to annotate. Self-supervised learning has shown to be an effective method for utilizing unlabeled data,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Mingu Kang , Heon Song , Seonwook Park , Donggeun Yoo , Sérgio Pereira

Recently, extensive deep learning architectures and pretraining strategies have been explored to support downstream protein applications. Additionally, domain-specific models incorporating biological knowledge have been developed to enhance…

Biomolecules · Quantitative Biology 2026-03-03 Shuo Yan , Yuliang Yan , Bin Ma , Chenao Li , Haochun Tang , Jiahua Lu , Minhua Lin , Yuyuan Feng , Enyan Dai

The performance of large language models (LLMs) is significantly affected by the quality and composition of their pre-training data, which is inherently diverse, spanning various languages, sources, and topics. Effectively integrating these…

Computation and Language · Computer Science 2025-08-11 Jiahui Peng , Xinlin Zhuang , Jiantao Qiu , Ren Ma , Jing Yu , He Zhu , Conghui He

The cross-lingual language models are typically pretrained with masked language modeling on multilingual text or parallel sentences. In this paper, we introduce denoising word alignment as a new cross-lingual pre-training task.…

Computation and Language · Computer Science 2021-09-14 Zewen Chi , Li Dong , Bo Zheng , Shaohan Huang , Xian-Ling Mao , Heyan Huang , Furu Wei

Effective document reranking is essential for improving search relevance across diverse applications. While Large Language Models (LLMs) excel at reranking due to their deep semantic understanding and reasoning, their high computational…

Computation and Language · Computer Science 2025-10-03 Dimitar Peshevski , Kiril Blazhevski , Martin Popovski , Gjorgji Madjarov

There have been various types of pretraining architectures including autoencoding models (e.g., BERT), autoregressive models (e.g., GPT), and encoder-decoder models (e.g., T5). However, none of the pretraining frameworks performs the best…

Computation and Language · Computer Science 2022-03-18 Zhengxiao Du , Yujie Qian , Xiao Liu , Ming Ding , Jiezhong Qiu , Zhilin Yang , Jie Tang

Pre-trained Transformers are challenging human performances in many NLP tasks. The massive datasets used for pre-training seem to be the key to their success on existing tasks. In this paper, we explore how a range of pre-trained Natural…

Large Language Models (LLMs) have transformed the natural language processing landscape and brought to life diverse applications. Pretraining on vast web-scale data has laid the foundation for these models, yet the research community is now…

Self-supervised learning has emerged as a powerful approach for leveraging large-scale unlabeled data to improve model performance in various domains. In this paper, we explore masked self-supervised pre-training for text recognition…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Martin Kišš , Michal Hradiš

While Large Language Models (LLMs) have exhibited remarkable emergent capabilities through extensive pre-training, they still face critical limitations in generalizing to specialized domains and handling diverse linguistic variations, known…

Computation and Language · Computer Science 2025-05-28 Jinwu Hu , Zhitian Zhang , Guohao Chen , Xutao Wen , Chao Shuai , Wei Luo , Bin Xiao , Yuanqing Li , Mingkui Tan

Training models on low-resource named entity recognition tasks has been shown to be a challenge, especially in industrial applications where deploying updated models is a continuous effort and crucial for business operations. In such cases…

Computation and Language · Computer Science 2019-10-18 Peter Izsak , Shira Guskin , Moshe Wasserblat

Masked language modeling (MLM) plays a key role in pretraining large language models. But the MLM objective is often dominated by high-frequency words that are sub-optimal for learning factual knowledge. In this work, we propose an approach…

Computation and Language · Computer Science 2023-04-05 Nafis Sadeq , Byungkyu Kang , Prarit Lamba , Julian McAuley

Pretraining Neural Language Models (NLMs) over a large corpus involves chunking the text into training examples, which are contiguous text segments of sizes processable by the neural architecture. We highlight a bias introduced by this…

Computation and Language · Computer Science 2022-03-22 Yoav Levine , Noam Wies , Daniel Jannai , Dan Navon , Yedid Hoshen , Amnon Shashua
‹ Prev 1 8 9 10 Next ›