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Effectively integrating multi-scale information is of considerable significance for the challenging multi-class segmentation of fundus lesions because different lesions vary significantly in scales and shapes. Several methods have been…
The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…
Early detection improves prognosis in pancreatic ductal adenocarcinoma (PDAC) but is challenging as lesions are often small and poorly defined on contrast-enhanced computed tomography scans (CE-CT). Deep learning can facilitate PDAC…
There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…
Prostate cancer is the second leading cause of cancer death among men in the United States. The diagnosis of prostate MRI often relies on the accurate prostate zonal segmentation. However, state-of-the-art automatic segmentation methods…
This paper presents Discriminative Part Network (DP-Net), a deep architecture with strong interpretation capabilities, which exploits a pretrained Convolutional Neural Network (CNN) combined with a part-based recognition module. This system…
Optical coherence tomography (OCT) is a commonly-used method of extracting high resolution retinal information. Moreover there is an increasing demand for the automated retinal layer segmentation which facilitates the retinal disease…
Accurate segmentation of organs from abdominal CT scans is essential for clinical applications such as diagnosis, treatment planning, and patient monitoring. To handle challenges of heterogeneity in organ shapes, sizes, and complex…
Accurate and automated tumor segmentation is highly desired since it has the great potential to increase the efficiency and reproducibility of computing more complete tumor measurements and imaging biomarkers, comparing to (often partial)…
Automated and accurate segmentation of individual vertebra in 3D CT and MRI images is essential for various clinical applications. Due to the limitations of current imaging techniques and the complexity of spinal structures, existing…
Fully convolutional neural networks have made promising progress in joint liver and liver tumor segmentation. Instead of following the debates over 2D versus 3D networks (for example, pursuing the balance between large-scale 2D pretraining…
Due to low tissue contrast, irregular object appearance, and unpredictable location variation, segmenting the objects from different medical imaging modalities (e.g., CT, MR) is considered as an important yet challenging task. In this…
The accurate segmentation of multiple types of lesions from adjacent tissues in medical images is significant in clinical practice. Convolutional neural networks (CNNs) based on the coarse-to-fine strategy have been widely used in this…
Precise segmentation of bladder walls and tumor regions is an essential step towards non-invasive identification of tumor stage and grade, which is critical for treatment decision and prognosis of patients with bladder cancer (BC). However,…
We propose a novel 3D fully convolutional deep network for automated pancreas segmentation from both MRI and CT scans. More specifically, the proposed model consists of a 3D encoder that learns to extract volume features at different…
The irregular geometry and high inter-slice variability in computerized tomography (CT) scans of the human pancreas make an accurate segmentation of this crucial organ a challenging task for existing data-driven deep learning methods. To…
Cervical cancer, the fourth leading cause of cancer in women globally, requires early detection through Pap smear tests to identify precancerous changes and prevent disease progression. In this study, we performed a focused analysis by…
Automated segmentation of individual calf muscle compartments from 3D magnetic resonance (MR) images is essential for developing quantitative biomarkers for muscular disease progression and its prediction. Achieving clinically acceptable…
Imposing key anatomical features, such as the number of organs, their shapes and relative positions, is crucial for building a robust multi-organ segmentation model. Current attempts to incorporate anatomical features include broadening the…
Direct automatic segmentation of objects from 3D medical imaging, such as magnetic resonance (MR) imaging, is challenging as it often involves accurately identifying a number of individual objects with complex geometries within a large…