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Foundation models have emerged as a powerful paradigm in computational pathology (CPath), enabling scalable and generalizable analysis of histopathological images. While early developments centered on uni-modal models trained solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Xiaohui Chen , Yi He , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Automated radiology report generation aims to expedite the tedious and error-prone reporting process for radiologists. While recent works have made progress, learning to align medical images and textual findings remains challenging due to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Yaxiong Chen , Chuang Du , Chunlei Li , Jingliang Hu , Yilei Shi , Shengwu Xiong , Xiao Xiang Zhu , Lichao Mou

Ultrasound (US) report generation is a challenging task due to the variability of US images, operator dependence, and the need for standardized text. Unlike X-ray and CT, US imaging lacks consistent datasets, making automation difficult. In…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Peixuan Ge , Tongkun Su , Faqin Lv , Baoliang Zhao , Peng Zhang , Chi Hong Wong , Liang Yao , Yu Sun , Zenan Wang , Pak Kin Wong , Ying Hu

The ability to learn from context with novel concepts, and deliver appropriate responses are essential in human conversations. Despite current Multimodal Large Language Models (MLLMs) and Large Language Models (LLMs) being trained on…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Yan Tai , Weichen Fan , Zhao Zhang , Feng Zhu , Rui Zhao , Ziwei Liu

Paucity of medical data severely limits the generalizability of diagnostic ML models, as the full spectrum of disease variability can not be represented by a small clinical dataset. To address this, diffusion models (DMs) have been…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Janet Wang , Yunbei Zhang , Zhengming Ding , Jihun Hamm

Contrastive vision-language models, such as CLIP, have demonstrated excellent zero-shot capability across semantic recognition tasks, mainly attributed to the training on a large-scale I&1T (one Image with one Text) dataset. This kind of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Zhichao Yang , Leida Li , Pengfei Chen , Jinjian Wu , Giuseppe Valenzise

Multimodal in-context learning (ICL) remains underexplored despite significant potential for domains such as medicine. Clinicians routinely encounter diverse, specialized tasks requiring adaptation from limited examples, such as drawing…

Medical report generation from imaging data remains a challenging task in clinical practice. While large language models (LLMs) show great promise in addressing this challenge, their effective integration with medical imaging data still…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Chunlei Li , Jingyang Hou , Yilei Shi , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Multimodal pathological image understanding has garnered widespread interest due to its potential to improve diagnostic accuracy and enable personalized treatment through integrated visual and textual data. However, existing methods exhibit…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Zhe Xu , Cheng Jin , Yihui Wang , Ziyi Liu , Hao Chen

Histopathological images (HIs) are the gold standard for evaluating some types of tumors for cancer diagnosis. The analysis of such images is not only time and resource consuming, but also very challenging even for experienced pathologists,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-09 Jonathan de Matos , Steve Tsham Mpinda Ataky , Alceu de Souza Britto , Luiz Eduardo Soares de Oliveira , Alessandro Lameiras Koerich

Large amounts of digitized histopathological data display a promising future for developing pathological foundation models via self-supervised learning methods. Foundation models pretrained with these methods serve as a good basis for…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Shengyi Hua , Fang Yan , Tianle Shen , Lei Ma , Xiaofan Zhang

Multimodal alignment of histopathology encoders with transcriptomic and genomic data has been shown to significantly improve performance in downstream diagnostic tasks. Hematological cytology is unique in that visual single-cell evaluation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Muhammed Furkan Dasdelen , Fatih Ozlugedik , Ilaria Looser , Rao Muhammad Umer , Christian Pohlkamp , Carsten Marr

Deep learning has advanced medical image classification, but interpretability challenges hinder its clinical adoption. This study enhances interpretability in Chest X-ray (CXR) classification by using concept bottleneck models (CBMs) and a…

Information Retrieval · Computer Science 2025-04-30 Hasan Md Tusfiqur Alam , Devansh Srivastav , Md Abdul Kadir , Daniel Sonntag

Automated CT report generation plays a crucial role in improving diagnostic accuracy and clinical workflow efficiency. However, existing methods lack interpretability and impede patient-clinician understanding, while their static nature…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Yannian Gu , Wenhui Lei , Hanyu Chen , Xiaofan Zhang , Shaoting Zhang

Recent research has investigated the underlying mechanisms of in-context learning (ICL) both theoretically and empirically, often using data generated from simple function classes. However, the existing work often focuses on the sequence…

Machine Learning · Computer Science 2025-03-03 Ziqian Lin , Shubham Kumar Bharti , Kangwook Lee

While Large Language Models (LLMs) are emerging as a promising direction in computational pathology, the substantial computational cost of giga-pixel Whole Slide Images (WSIs) necessitates the use of Multi-Instance Learning (MIL) to enable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Zhenfeng Zhuang , Fangyu Zhou , Liansheng Wang

Although existing CLIP-based methods for detecting AI-generated images have achieved promising results, they are still limited by severe feature redundancy, which hinders their generalization ability. To address this issue, incorporating an…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Haotian Qin , Dongliang Chang , Yueying Gao , Bingyao Yu , Lei Chen , Zhanyu Ma

Histopathological imaging is vital for cancer research and clinical practice, with multiplexed Immunofluorescence (MxIF) and Hematoxylin and Eosin (H&E) providing complementary insights. However, aligning different stains at the cell level…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jun Jiang , Raymond Moore , Brenna Novotny , Leo Liu , Zachary Fogarty , Ray Guo , Markovic Svetomir , Chen Wang

Multiple Instance Learning (MIL) methods allow for gigapixel Whole-Slide Image (WSI) analysis with only slide-level annotations. Interpretability is crucial for safely deploying such algorithms in high-stakes medical domains. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Susu Sun , Leslie Tessier , Frédérique Meeuwsen , Clément Grisi , Dominique van Midden , Geert Litjens , Christian F. Baumgartner

Radiology report generation aims to automatically generate a clinically accurate and coherent paragraph from the X-ray image, which could relieve radiologists from the heavy burden of report writing. Although various image caption methods…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Zhongzhen Huang , Xiaofan Zhang , Shaoting Zhang