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Optimization in the latent space of variational autoencoders is a promising approach to generate high-dimensional discrete objects that maximize an expensive black-box property (e.g., drug-likeness in molecular generation, function…

Machine Learning · Computer Science 2021-07-02 Pascal Notin , José Miguel Hernández-Lobato , Yarin Gal

Quantum computing promises a new approach to solving difficult computational problems, and the quest of building a quantum computer has started. While the first attempts on construction were succesful, scalability has never been achieved,…

Quantum Physics · Physics 2014-08-01 Alexandru Paler , Simon J. Devitt , Kae Nemoto , Ilia Polian

The simulation of quantum dynamics calls for quantum algorithms working in first quantized grid encodings. Here, we propose a variational quantum algorithm for performing quantum dynamics in first quantization. In addition to the usual…

While quantum machine learning (ML) has been proposed to be one of the most promising applications of quantum computing, how to build quantum ML models that outperform classical ML remains a major open question. Here, we demonstrate a…

Quantum Physics · Physics 2023-03-10 Elham Torabian , Roman V. Krems

Variational quantum algorithms (VQAs) are a modern family of quantum algorithms designed to solve optimization problems using a quantum computer. Typically VQAs rely on a feedback loop between the quantum device and a classical optimization…

Quantum Physics · Physics 2022-08-26 Alexey Uvarov

Recent days have witnessed significant interests in applying quantum-enhanced techniques for solving a variety of machine learning tasks. Variational methods that use quantum resources of imperfect quantum devices with the help of classical…

Quantum Physics · Physics 2021-11-15 Hiroshi Yano , Yudai Suzuki , Kohei M. Itoh , Rudy Raymond , Naoki Yamamoto

We propose a gate optimization method, which we call variational quantum gate optimization (VQGO). VQGO is a method to construct a target multi-qubit gate by optimizing a parametrized quantum circuit which consists of tunable single-qubit…

Quantum Physics · Physics 2018-10-31 Kentaro Heya , Yasunari Suzuki , Yasunobu Nakamura , Keisuke Fujii

Current universal quantum computers have a limited number of noisy qubits. Because of this, it is difficult to use them to solve large-scale complex optimization problems. In this paper we tackle this issue by proposing a quantum…

Quantum Physics · Physics 2023-06-30 Pablo Bermejo , Roman Orus

Optimization problems are critical across various domains, yet existing quantum algorithms, despite their great potential, struggle with scalability and accuracy due to excessive reliance on entanglement. To address these limitations, we…

Quantum Physics · Physics 2025-03-04 Seongmin Kim , In-Saeng Suh

Multivariate (MTV) porous materials exhibit unique structural complexities based on diverse spatial arrangements of multiple building block combinations. These materials possess potential synergistic functionalities that exceed the sum of…

Quantum Physics · Physics 2025-05-12 Shinyoung Kang , Younghun Kim , Jihan Kim

In the context of quantum information, highly nonlinear regimes, such as those supporting solitons, are marginally investigated. We miss general methods for quantum solitons, although they can act as entanglement generators or as…

Quantum Physics · Physics 2022-08-31 Claudio Conti

Variational quantum algorithms involve training parameterized quantum circuits using a classical co-processor. An important variational algorithm, designed for combinatorial optimization, is the quantum approximate optimization algorithm.…

The standard paradigm for state preparation on quantum computers for the simulation of physical systems in the near term has been widely explored with different algorithmic methods. One such approach is the optimization of parameterized…

Quantum Physics · Physics 2023-01-18 J. Wayne Mullinax , Norm M. Tubman

Variational quantum algorithms, which have risen to prominence in the noisy intermediate-scale quantum setting, require the implementation of a stochastic optimizer on classical hardware. To date, most research has employed algorithms based…

Quantum Physics · Physics 2023-03-22 Matt Menickelly , Yunsoo Ha , Matthew Otten

This work proposes a hybrid framework combining classical computers with quantum annealers for structural optimisation. At each optimisation iteration of an iterative process, two minimisation problems are formulated one for the underlying…

Computational Engineering, Finance, and Science · Computer Science 2025-10-27 Van-Dung Nguyen , Erin Kuci , Michel Rasquin , Ludovic Noels

Hybrid quantum/classical variational algorithms can be implemented on noisy intermediate-scale quantum computers and can be used to find solutions for combinatorial optimization problems. Approaches discussed in the literature minimize the…

With rapid advances in quantum hardware, a central question is whether quantum devices with or without full error correction can outperform classical computers on practically relevant problems. Variational Quantum Algorithms (VQAs) have…

Quantum Physics · Physics 2025-09-09 Adelina Bärligea , Benedikt Poggel , Jeanette Miriam Lorenz

Combining quantum computers with classical compute power has become a standard means for developing algorithms that are eventually supposed to beat any purely classical alternatives. While in-principle advantages for solution quality or…

Quantum Physics · Physics 2026-01-23 Simon Thelen , Wolfgang Mauerer

Variational quantum circuits (VQCs) hold promise for quantum machine learning but face challenges in expressivity, trainability, and noise resilience. We propose VQC-MLPNet, a hybrid architecture where a VQC generates the first-layer…

Quantum Physics · Physics 2025-11-06 Jun Qi , Chao-Han Yang , Pin-Yu Chen , Min-Hsiu Hsieh

Variational quantum circuits (VQCs) are an essential tool in applying noisy intermediate-scale quantum computers to practical problems. VQCs are used as a central component in many algorithms, for example, in quantum machine learning,…

Quantum Physics · Physics 2025-12-18 Joona V. Pankkonen , Lauri Ylinen , Matti Raasakka , Ilkka Tittonen