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Solving electronic structure problems is considered one of the most promising applications of quantum computing. However, due to limitations imposed by the coherence time of qubits in the Noisy Intermediate Scale Quantum (NISQ) era or the…

Quantum Physics · Physics 2025-03-20 Shuo Sun , Chandan Kumar , Kevin Shen , Elvira Shishenina , Christian B. Mendl

Growing uncertainty from renewable energy integration and distributed energy resources motivate the need for advanced tools to quantify the effect of uncertainty and assess the risks it poses to secure system operation. Polynomial chaos…

Optimization and Control · Mathematics 2019-10-16 David Métivier , Marc Vuffray , Sidhant Misra

Pauli-based computation (PBC) is a universal measurement-based quantum computation model steered by an adaptive sequence of independent and compatible Pauli measurements on separable magic-state qubits. Here, we propose several new…

Quantum Physics · Physics 2025-12-03 Filipa C. R. Peres , Ernesto F. Galvão

Polynomial chaos expansion (PCE) is a classical and widely used surrogate modeling technique in physical simulation and uncertainty quantification. By taking a linear combination of a set of basis polynomials - orthonormal with respect to…

Machine Learning · Computer Science 2026-04-01 Johannes Exenberger , Sascha Ranftl , Robert Peharz

Atom loss is a major error source in neutral-atom quantum computers, accounting for over 40% of the total physical errors in recent experiments. Its nonlinear and correlated nature poses significant challenges: current syndrome extraction…

Quantum Physics · Physics 2026-04-07 Pengyu Liu , Shi Jie Samuel Tan , Eric Huang , Umut A. Acar , Hengyun Zhou , Chen Zhao

The Poisson-Boltzmann equation (PBE) is a nonlinear elliptic PDE that arises in biomolecular modeling and is a fundamental tool for structural biology. It is used to calculate electrostatic potentials around an ensemble of fixed charges…

Numerical Analysis · Mathematics 2017-10-12 Cleophas Kweyu , Lihong Feng , Matthias Stein , Peter Benner

Combinatorial optimization on near-term quantum devices is a promising path to demonstrating quantum advantage. However, the capabilities of these devices are constrained by high noise or error rates. In this paper, we propose an iterative…

Quantum Physics · Physics 2022-05-12 Xiaoyuan Liu , Anthony Angone , Ruslan Shaydulin , Ilya Safro , Yuri Alexeev , Lukasz Cincio

Polynomial chaos expansion (PCE) is a versatile tool widely used in uncertainty quantification and machine learning, but its successful application depends strongly on the accuracy and reliability of the resulting PCE-based response…

Computation · Statistics 2023-06-14 Paul-Christian Bürkner , Ilja Kröker , Sergey Oladyshkin , Wolfgang Nowak

Real quantum computers will be subject to complicated, qubit-dependent noise, instead of simple noise such as depolarizing noise with the same strength for all qubits. We can do quantum error correction more effectively if our decoding…

Quantum Physics · Physics 2024-11-20 Alex Fischer , Akimasa Miyake

Surface codes represent a leading approach for quantum error correction (QEC), offering a path towards universal fault-tolerant quantum computing (FTQC). However, efficiently implementing algorithms, particularly using Pauli-based…

Quantum Physics · Physics 2025-05-02 Shuwen Kan , Zefan Du , Chenxu Liu , Meng Wang , Yufei Ding , Ang Li , Ying Mao , Samuel Stein

Block-encodings of matrices have become an essential element of quantum algorithms derived from the quantum singular value transformation. This includes a variety of algorithms ranging from the quantum linear systems problem to quantum…

Quantum Physics · Physics 2023-06-13 Daan Camps , Roel Van Beeumen

Partial differential equations (PDEs) are central to modeling physical and engineering systems, but repeatedly solving parametric PDEs remains computationally expensive. Operator learning enables fast surrogate inference, yet typically…

Quantum Physics · Physics 2026-05-28 Chanyoung Kim , Myeonghwan Seong , Yujin Kim , Daniel K. Park , Youngjoon Hong

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

Pauli-based computation (PBC) is a universal model for quantum computation with qubits where the input state is a magic (resource) state and the computation is driven by a sequence of adaptively chosen and compatible multiqubit Pauli…

Quantum Physics · Physics 2023-09-15 Filipa C. R. Peres

We present a new hybrid quantum-classical algorithm for optimizing unitary coupled-cluster (UCC) wave functions deemed the projective quantum eigensolver (PQE), amenable to near-term noisy quantum hardware. Contrary to variational quantum…

Quantum Physics · Physics 2021-08-10 Nicholas H. Stair , Francesco A. Evangelista

Variational Quantum Algorithms (VQAs) provide a promising framework for tackling complex optimization problems on near-term quantum hardware. Here, we demonstrate that hybrid qubit--qumode quantum devices offer an efficient route to solving…

While recent breakthroughs have proven the ability of noisy intermediate-scale quantum (NISQ) devices to achieve quantum advantage in classically-intractable sampling tasks, the use of these devices for solving more practically relevant…

Different hybrid quantum-classical algorithms have recently been developed as a near-term way to solve linear systems of equations on quantum devices. However, the focus has so far been mostly on the methods, rather than the problems that…

Computational Engineering, Finance, and Science · Computer Science 2024-12-09 Giorgio Tosti Balducci , Boyang Chen , Matthias Möller , Roeland De Breuker

Quantum and Classical computers continue to work together in tight cooperation to solve difficult problems. The combination is thus suggested in recent times for decoding the Low Density Parity Check (LDPC) codes, for the next generation…

Quantum Physics · Physics 2022-09-27 Utso Majumder , Aditya Das Sarma , Vishnu Vaidya , M Girish Chandra

In this study, we study the Variational Quantum Eigensolver (VQE) application for the Ising model as a test bed model, in which we pivotally delved into several optimization methods, both classical and quantum, and analyzed the quantum…

Quantum Physics · Physics 2025-04-21 Duc-Truyen Le , Vu-Linh Nguyen , Cong-Ha Nguyen , Quoc-Hung Nguyen , Van-Duy Nguyen